Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Melanogenesis 💬
1件: EDNRB 💬 Bosentan 💬 Bosentan 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2 Melanogenesis 💬
1件: EDNRB 💬 Bosentan 💬 Bosentan 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
3 Melanogenesis 💬
1件: EDNRB 💬 Macitentan 💬 Macitentan 5件: 51, 85, 86, 88, 210 💬
4 Melanogenesis 💬
1件: KIT 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
5 Melanogenesis 💬
1件: KIT 💬 Barzolvolimab 💬 Barzolvolimab 1件: 98 💬
6 Melanogenesis 💬
1件: KIT 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
7 Melanogenesis 💬
1件: KIT 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
8 Melanogenesis 💬
1件: KIT 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
9 Melanogenesis 💬
1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
10 Melanogenesis 💬
1件: KIT 💬 Masitinib 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬
11 Melanogenesis 💬
1件: KIT 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
12 Melanogenesis 💬
1件: KIT 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
13 Melanogenesis 💬
1件: KIT 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
14 Melanogenesis 💬
1件: KIT 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
15 Melanogenesis 💬
2件: KIT, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
16 Melanogenesis 💬
2件: KIT, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
17 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
18 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
19 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
20 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
21 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
22 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
23 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
24 Melanogenesis 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
25 Melanogenesis 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
26 Melanogenesis 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
27 Melanogenesis 💬
1件: MC1R 💬 Dersimelagon 💬 Dersimelagon 2件: 51, 254 💬
28 Melanogenesis 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
29 Melanogenesis 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬