Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
ALOX15 1件: ALOX15 💬
|
Utreloxastat Utreloxastat 💬
| Utreloxastat | 002 1件: 2 💬
|
| 2 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
BCL2 1件: BCL2 💬
|
Obatoclax mesylate Obatoclax mesylate 💬
| Obatoclax | 060 1件: 60 💬
|
| 3 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
BCL2 1件: BCL2 💬
|
Venetoclax Venetoclax 💬
| Venetoclax | 028 2件: 28, 85 💬
|
| 4 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNA 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬
|
Sifalimumab Sifalimumab 💬
| Sifalimumab | 049 1件: 49 💬
|
| 5 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNA 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬
|
Rontalizumab Rontalizumab 💬
| Rontalizumab | 049 1件: 49 💬
|
| 6 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Anifrolumab Anifrolumab 💬
| Anifrolumab | 046 5件: 46, 49, 50, 51, 53 💬
|
| 7 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon beta Interferon beta 💬
| Human interferon beta | 013 5件: 13, 20, 50, 96, 97 💬
|
| 8 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon alfa Interferon alfa 💬
| Interferon alfa | 025 2件: 25, 56 💬
|
| 9 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon alfa-2a Interferon alfa-2a 💬
| Interferon alfa-2a | 056 1件: 56 💬
|
| 10 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon alfa-2b Interferon alfa-2b 💬
| Interferon alfa-2b | 025 1件: 25 💬
|
| 11 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon beta-1a Interferon beta-1a 💬
| Interferon beta-1a | 013 3件: 13, 96, 97 💬
|
| 12 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Interferon beta-1b Interferon beta-1b 💬
| Interferon beta-1b | 013 1件: 13 💬
|
| 13 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Peginterferon alfa-2a Peginterferon alfa-2a 💬
| Peginterferon alfa-2a | 222 1件: 222 💬
|
| 14 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNAR1 2件: IFNAR1, IFNAR2 💬
|
Peginterferon beta-1a Peginterferon beta-1a 💬
| Peginterferon beta-1a | 013 1件: 13 💬
|
| 15 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNB 1件: IFNB 💬
|
Dazukibart Dazukibart 💬
| Dazukibart | 050 1件: 50 💬
|
| 16 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNG 1件: IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 5件: 49, 54, 60, 65, 107 💬
|
| 17 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNG 1件: IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 1件: 46 💬
|
| 18 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬
|
Interferon gamma-1b Interferon gamma-1b 💬
| Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬
|
| 19 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 20 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Lutikizumab Lutikizumab 💬
| Lutikizumab | 046 3件: 46, 96, 97 💬
|
| 21 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 5件: 51, 84, 106, 107, 266 💬
|
| 22 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1A 3件: IL1A, IL1B, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 23 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
| 24 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 25 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
IL33 1件: IL33 💬
|
Itepekimab Itepekimab 💬
| Itepekimab | 299 1件: 299 💬
|
| 26 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Abrocitinib Abrocitinib 💬
| Abrocitinib | 039 2件: 39, 84 💬
|
| 27 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Filgotinib Filgotinib 💬
| Filgotinib | 046 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
|
| 28 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Itacitinib Itacitinib 💬
| Itacitinib | 046 4件: 46, 51, 97, 228 💬
|
| 29 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Itacitinib adipate Itacitinib adipate 💬
| Itacitinib | 046 4件: 46, 51, 97, 228 💬
|
| 30 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib Upadacitinib 💬
| Upadacitinib | 040 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
|
| 31 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib tartrate Upadacitinib tartrate 💬
| Upadacitinib | 040 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
|
| 32 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 1件: JAK1 💬
|
Upadacitinib hydrate Upadacitinib hydrate 💬
| Upadacitinib | 040 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
|
| 33 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Baricitinib Baricitinib 💬
| Baricitinib | 002 21件: 2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
|
| 34 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Ruxolitinib Ruxolitinib 💬
| Ruxolitinib | 013 6件: 13, 15, 50, 60, 65, 228 💬
|
| 35 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 2件: JAK1, JAK2 💬
|
Ruxolitinib phosphate Ruxolitinib phosphate 💬
| Ruxolitinib | 013 6件: 13, 15, 50, 60, 65, 228 💬
|
| 36 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Gusacitinib Gusacitinib 💬
| Gusacitinib | 049 1件: 49 💬
|
| 37 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬
|
Peficitinib Peficitinib 💬
| Peficitinib | 046 1件: 46 💬
|
| 38 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Delgocitinib Delgocitinib 💬
| Delgocitinib | 050 1件: 50 💬
|
| 39 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Filgotinib maleate Filgotinib maleate 💬
| Filgotinib | 046 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
|
| 40 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib citrate Tofacitinib citrate 💬
| Tofacitinib | 002 22件: 2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
|
| 41 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬
|
Tofacitinib Tofacitinib 💬
| Tofacitinib | 002 22件: 2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
|
| 42 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK2 1件: JAK2 💬
|
Pacritinib Pacritinib 💬
| Pacritinib | 331 1件: 331 💬
|
| 43 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
JAK3 1件: JAK3 💬
|
Ritlecitinib tosylate Ritlecitinib tosylate 💬
| Ritlecitinib | 046 3件: 46, 96, 97 💬
|
| 44 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
PARP1 1件: PARP1 💬
|
Olaparib Olaparib 💬
| Olaparib | 086 2件: 86, 285 💬
|
| 45 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
RIPK1 1件: RIPK1 💬
|
Eclitasertib Eclitasertib 💬
| SAR443122 | 097 1件: 97 💬
|
| 46 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
SMPD1 1件: SMPD1 💬
|
Olipudase alfa Olipudase alfa 💬
| Olipudase alfa | 019 1件: 19 💬
|
| 47 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
|
| 48 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 7件: 37, 46, 49, 96, 107, 226, 271 💬
|
| 49 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
|
| 50 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 51 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
|
| 52 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 53 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 1件: 46 💬
|
| 54 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 1件: 46 💬
|
| 55 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬
|
| 56 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 21件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
|
| 57 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TYK2 1件: TYK2 💬
|
Deucravacitinib Deucravacitinib 💬
| Deucravacitinib | 036 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
|
| 58 | Necroptosis 💬 32 genes, 52 drugs (DrugBank) and 77 diseases |
TYK2 1件: TYK2 💬
|
Zasocitinib Zasocitinib 💬
| Zasocitinib | 096 2件: 96, 97 💬
|