Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Signaling pathways regulating pluripotency of stem cells 💬
 1件: ACVR1 💬 Fidrisertib 💬 Fidrisertib 1件: 272 💬
2 Signaling pathways regulating pluripotency of stem cells 💬
 1件: ACVR1 💬 Zilurgisertib 💬 Zilurgisertib 1件: 272 💬
3 Signaling pathways regulating pluripotency of stem cells 💬
 1件: ACVR2A 💬 Sotatercept 💬 Sotatercept 2件: 86, 284 💬
4 Signaling pathways regulating pluripotency of stem cells 💬
 2件: ACVR2A, ACVR2B 💬 Bimagrumab 💬 Bimagrumab 1件: 15 💬
5 Signaling pathways regulating pluripotency of stem cells 💬
 1件: ACVR2B 💬 Luspatercept 💬 Luspatercept 3件: 60, 61, 282 💬
6 Signaling pathways regulating pluripotency of stem cells 💬
 3件: FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib 1件: 276 💬
7 Signaling pathways regulating pluripotency of stem cells 💬
 3件: FGFR1, FGFR2, FGFR3 💬 Infigratinib phosphate 💬 Infigratinib 1件: 276 💬
8 Signaling pathways regulating pluripotency of stem cells 💬
 3件: FGFR1, FGFR2, FGFR3 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
9 Signaling pathways regulating pluripotency of stem cells 💬
 3件: FGFR1, FGFR2, FGFR3 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
10 Signaling pathways regulating pluripotency of stem cells 💬
 4件: FGFR1, FGFR2, FGFR3, FGFR4 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
11 Signaling pathways regulating pluripotency of stem cells 💬
 1件: FGFR2 💬 Palifermin 💬 Palifermin 6件: 13, 36, 38, 39, 65, 96 💬
12 Signaling pathways regulating pluripotency of stem cells 💬
 1件: FGFR3 💬 Recifercept 💬 Recifercept 1件: 276 💬
13 Signaling pathways regulating pluripotency of stem cells 💬
 1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
14 Signaling pathways regulating pluripotency of stem cells 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
15 Signaling pathways regulating pluripotency of stem cells 💬
 1件: IGF1R 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
16 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
17 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
18 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
19 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
20 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
21 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
22 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
23 Signaling pathways regulating pluripotency of stem cells 💬
 2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
24 Signaling pathways regulating pluripotency of stem cells 💬
 2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
25 Signaling pathways regulating pluripotency of stem cells 💬
 2件: JAK1, JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
26 Signaling pathways regulating pluripotency of stem cells 💬
 3件: JAK1, JAK2, JAK3 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
27 Signaling pathways regulating pluripotency of stem cells 💬
 3件: JAK1, JAK2, JAK3 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
28 Signaling pathways regulating pluripotency of stem cells 💬
 3件: JAK1, JAK2, JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
29 Signaling pathways regulating pluripotency of stem cells 💬
 3件: JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
30 Signaling pathways regulating pluripotency of stem cells 💬
 3件: JAK1, JAK2, JAK3 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
31 Signaling pathways regulating pluripotency of stem cells 💬
 3件: JAK1, JAK2, JAK3 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
32 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
33 Signaling pathways regulating pluripotency of stem cells 💬
 1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
34 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
35 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
36 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
37 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
38 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
39 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
40 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
41 Signaling pathways regulating pluripotency of stem cells 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
42 Signaling pathways regulating pluripotency of stem cells 💬
 4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
43 Signaling pathways regulating pluripotency of stem cells 💬
 4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
44 Signaling pathways regulating pluripotency of stem cells 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
45 Signaling pathways regulating pluripotency of stem cells 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
46 Signaling pathways regulating pluripotency of stem cells 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
47 Signaling pathways regulating pluripotency of stem cells 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
48 Signaling pathways regulating pluripotency of stem cells 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
49 Signaling pathways regulating pluripotency of stem cells 💬
 1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
50 Signaling pathways regulating pluripotency of stem cells 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬