Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Non-small cell lung cancer 💬
 1件: ALK 💬 Brigatinib 💬 Brigatinib 1件: 34 💬
2 Non-small cell lung cancer 💬
 1件: ALK 💬 Crizotinib 💬 Crizotinib 2件:  2 , 34 💬
3 Non-small cell lung cancer 💬
 1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
4 Non-small cell lung cancer 💬
 1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
5 Non-small cell lung cancer 💬
 3件: BRAF, RAF1, RET 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
6 Non-small cell lung cancer 💬
 3件: BRAF, RAF1, RET 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
7 Non-small cell lung cancer 💬
 1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
8 Non-small cell lung cancer 💬
 2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
9 Non-small cell lung cancer 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
10 Non-small cell lung cancer 💬
 1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
11 Non-small cell lung cancer 💬
 1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
12 Non-small cell lung cancer 💬
 1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
13 Non-small cell lung cancer 💬
 1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
14 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Afatinib 💬 Afatinib 1件: 285 💬
15 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
16 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
17 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
18 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Neratinib 💬 Neratinib 1件: 34 💬
19 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
20 Non-small cell lung cancer 💬
 2件: EGFR, ERBB2 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
21 Non-small cell lung cancer 💬
 1件: JAK3 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
22 Non-small cell lung cancer 💬
 1件: JAK3 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
23 Non-small cell lung cancer 💬
 1件: JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
24 Non-small cell lung cancer 💬
 1件: JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
25 Non-small cell lung cancer 💬
 1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
26 Non-small cell lung cancer 💬
 1件: JAK3 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
27 Non-small cell lung cancer 💬
 1件: JAK3 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
28 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
29 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
30 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
31 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
32 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
33 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
34 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
35 Non-small cell lung cancer 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
36 Non-small cell lung cancer 💬
 1件: MET 💬 Cabozantinib 💬 Cabozantinib 1件: 34 💬
37 Non-small cell lung cancer 💬
 1件: MET 💬 Cabozantinib s-malate 💬 Cabozantinib 1件: 34 💬
38 Non-small cell lung cancer 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
39 Non-small cell lung cancer 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
40 Non-small cell lung cancer 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
41 Non-small cell lung cancer 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
42 Non-small cell lung cancer 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
43 Non-small cell lung cancer 💬
 1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
44 Non-small cell lung cancer 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
45 Non-small cell lung cancer 💬
 1件: RARB 💬 Fenretinide 💬 Fenretinide 1件: 299 💬
46 Non-small cell lung cancer 💬
 1件: RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
47 Non-small cell lung cancer 💬
 1件: RARB 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
48 Non-small cell lung cancer 💬
 1件: RARB 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬
49 Non-small cell lung cancer 💬
 4件: RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬
50 Non-small cell lung cancer 💬
 4件: RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
51 Non-small cell lung cancer 💬
 2件: RARB, RXRB 💬 Tazarotene 💬 Tazarotene 1件: 85 💬
52 Non-small cell lung cancer 💬
 1件: RET 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
53 Non-small cell lung cancer 💬
 1件: RET 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
54 Non-small cell lung cancer 💬
 3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬
55 Small cell lung cancer 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
56 Small cell lung cancer 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
57 Small cell lung cancer 💬
 1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
58 Small cell lung cancer 💬
 2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
59 Small cell lung cancer 💬
 1件: ITGB1 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
60 Small cell lung cancer 💬
 1件: ITGB1 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
61 Small cell lung cancer 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
62 Small cell lung cancer 💬
 1件: NOS2 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
63 Small cell lung cancer 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
64 Small cell lung cancer 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
65 Small cell lung cancer 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
66 Small cell lung cancer 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
67 Small cell lung cancer 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
68 Small cell lung cancer 💬
 1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
69 Small cell lung cancer 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
70 Small cell lung cancer 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
71 Small cell lung cancer 💬
 1件: PTGS2 💬 Celecoxib 💬 Celecoxib 14件:  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
72 Small cell lung cancer 💬
 1件: PTGS2 💬 Diclofenac potassium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
73 Small cell lung cancer 💬
 1件: PTGS2 💬 Diclofenac sodium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
74 Small cell lung cancer 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 4件: 13, 34, 46, 271 💬
75 Small cell lung cancer 💬
 1件: PTGS2 💬 Diclofenac diethylamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
76 Small cell lung cancer 💬
 1件: PTGS2 💬 Diclofenac epolamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
77 Small cell lung cancer 💬
 1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
78 Small cell lung cancer 💬
 1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 3件: 46, 70, 271 💬
79 Small cell lung cancer 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
80 Small cell lung cancer 💬
 1件: PTGS2 💬 Flurbiprofen sodium 💬 Flurbiprofen 3件: 13, 21, 46 💬
81 Small cell lung cancer 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
82 Small cell lung cancer 💬
 1件: PTGS2 💬 Ibuprofen aluminum 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
83 Small cell lung cancer 💬
 1件: PTGS2 💬 Ibuprofen lysine 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
84 Small cell lung cancer 💬
 1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
85 Small cell lung cancer 💬
 1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
86 Small cell lung cancer 💬
 1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
87 Small cell lung cancer 💬
 1件: PTGS2 💬 Indomethacin sodium 💬 Indomethacin 3件: 225, 271, 298 💬
88 Small cell lung cancer 💬
 1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 2件: 13, 46 💬
89 Small cell lung cancer 💬
 1件: PTGS2 💬 Ketoprofen lysine 💬 Ketoprofen 2件: 13, 46 💬
90 Small cell lung cancer 💬
 1件: PTGS2 💬 Ketoprofen sodium 💬 Ketoprofen 2件: 13, 46 💬
91 Small cell lung cancer 💬
 1件: PTGS2 💬 Ketorolac tromethamine 💬 Ketorolac 2件: 70, 226 💬
92 Small cell lung cancer 💬
 1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
93 Small cell lung cancer 💬
 1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
94 Small cell lung cancer 💬
 1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
95 Small cell lung cancer 💬
 1件: PTGS2 💬 Meloxicam 💬 Meloxicam 3件: 46, 271, 296 💬
96 Small cell lung cancer 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
97 Small cell lung cancer 💬
 1件: PTGS2 💬 Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
98 Small cell lung cancer 💬
 1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
99 Small cell lung cancer 💬
 1件: PTGS2 💬 Valdecoxib 💬 Parecoxib 2件: 46, 271 💬
100 Small cell lung cancer 💬
 1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
101 Small cell lung cancer 💬
 1件: PTGS2 💬 Parecoxib sodium 💬 Parecoxib 2件: 46, 271 💬
102 Small cell lung cancer 💬
 1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
103 Small cell lung cancer 💬
 1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
104 Small cell lung cancer 💬
 1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
105 Small cell lung cancer 💬
 1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
106 Small cell lung cancer 💬
 1件: RARB 💬 Fenretinide 💬 Fenretinide 1件: 299 💬
107 Small cell lung cancer 💬
 1件: RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
108 Small cell lung cancer 💬
 1件: RARB 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
109 Small cell lung cancer 💬
 1件: RARB 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬
110 Small cell lung cancer 💬
 4件: RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬
111 Small cell lung cancer 💬
 4件: RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
112 Small cell lung cancer 💬
 2件: RARB, RXRB 💬 Tazarotene 💬 Tazarotene 1件: 85 💬
113 Small cell lung cancer 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
114 Small cell lung cancer 💬
 3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬

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