Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Taste transduction 💬
1件: CACNA1C 💬 Amlodipine besylate 💬 Amlodipine 3件: 51, 67, 298 💬
2 Taste transduction 💬
1件: CACNA1C 💬 Amlodipine maleate 💬 Amlodipine 3件: 51, 67, 298 💬
3 Taste transduction 💬
1件: CACNA1C 💬 Amlodipine 💬 Amlodipine 3件: 51, 67, 298 💬
4 Taste transduction 💬
1件: CACNA1C 💬 Amlodipine benzoate 💬 Amlodipine 3件: 51, 67, 298 💬
5 Taste transduction 💬
1件: CACNA1C 💬 Bevantolol hydrochloride 💬 Bevantolol 1件:  8  💬
6 Taste transduction 💬
1件: CACNA1C 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
7 Taste transduction 💬
1件: CACNA1C 💬 Diltiazem hydrochloride 💬 Diltiazem 4件: 51, 58, 86, 88 💬
8 Taste transduction 💬
1件: CACNA1C 💬 Diltiazem malate 💬 Diltiazem 4件: 51, 58, 86, 88 💬
9 Taste transduction 💬
1件: CACNA1C 💬 Diltiazem 💬 Diltiazem 4件: 51, 58, 86, 88 💬
10 Taste transduction 💬
1件: CACNA1C 💬 Isradipine 💬 Isradipine 1件:  6  💬
11 Taste transduction 💬
1件: CACNA1C 💬 Nicardipine hydrochloride 💬 Nicardipine 2件: 70, 86 💬
12 Taste transduction 💬
1件: CACNA1C 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
13 Taste transduction 💬
1件: CACNA1C 💬 Nifedipine 💬 Nifedipine 1件: 81 💬
14 Taste transduction 💬
1件: CACNA1C 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
15 Taste transduction 💬
1件: CACNA1C 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
16 Taste transduction 💬
1件: CACNA1C 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
17 Taste transduction 💬
1件: CACNA1C 💬 Verapamil hydrochloride 💬 Verapamil 4件: 58, 96, 140, 167 💬
18 Taste transduction 💬
1件: CACNA1C 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
19 Taste transduction 💬
2件: CACNA1C, CHRM3 💬 Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
20 Taste transduction 💬
2件: CACNA1C, CHRM3 💬 Propiverine 💬 Propiverine 1件: 226 💬
21 Taste transduction 💬
10件: CACNA1C, GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, SCN2A, SCN3A, SCN9A 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
22 Taste transduction 💬
1件: CHRM3 💬 Atropine 💬 Atropine 1件: 299 💬
23 Taste transduction 💬
1件: CHRM3 💬 Atropine sulfate 💬 Atropine 1件: 299 💬
24 Taste transduction 💬
1件: CHRM3 💬 Bethanechol chloride 💬 Bethanechol 1件: 98 💬
25 Taste transduction 💬
1件: CHRM3 💬 Blarcamesine 💬 Blarcamesine 2件:  6 , 156 💬
26 Taste transduction 💬
1件: CHRM3 💬 Blarcamesine hydrochloride 💬 Blarcamesine 2件:  6 , 156 💬
27 Taste transduction 💬
1件: CHRM3 💬 Cevimeline hydrochloride 💬 Cevimeline 1件: 53 💬
28 Taste transduction 💬
1件: CHRM3 💬 Cevimeline 💬 Cevimeline 1件: 53 💬
29 Taste transduction 💬
1件: CHRM3 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
30 Taste transduction 💬
1件: CHRM3 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
31 Taste transduction 💬
1件: CHRM3 💬 Darifenacin hydrobromide 💬 Darifenacin 3件:  2 , 13, 26 💬
32 Taste transduction 💬
1件: CHRM3 💬 Darifenacin 💬 Darifenacin 3件:  2 , 13, 26 💬
33 Taste transduction 💬
1件: CHRM3 💬 Fesoterodine 💬 Fesoterodine 1件:  6  💬
34 Taste transduction 💬
1件: CHRM3 💬 Fesoterodine fumarate 💬 Fesoterodine 1件:  6  💬
35 Taste transduction 💬
1件: CHRM3 💬 Glycopyrrolate 💬 Glycopyrronium 2件:  6 , 34 💬
36 Taste transduction 💬
1件: CHRM3 💬 Glycopyrronium 💬 Glycopyrronium 2件:  6 , 34 💬
37 Taste transduction 💬
1件: CHRM3 💬 Glycopyrronium tosylate 💬 Glycopyrronium 2件:  6 , 34 💬
38 Taste transduction 💬
1件: CHRM3 💬 Methacholine chloride 💬 Methacholine 1件: 96 💬
39 Taste transduction 💬
1件: CHRM3 💬 Oxybutynin 💬 Oxybutynin 3件:  6 , 13, 53 💬
40 Taste transduction 💬
1件: CHRM3 💬 Oxybutynin chloride 💬 Oxybutynin 3件:  6 , 13, 53 💬
41 Taste transduction 💬
1件: CHRM3 💬 Pilocarpine 💬 Pilocarpine 3件:  6 , 53, 299 💬
42 Taste transduction 💬
1件: CHRM3 💬 Pilocarpine hydrochloride 💬 Pilocarpine 3件:  6 , 53, 299 💬
43 Taste transduction 💬
1件: CHRM3 💬 Pilocarpine nitrate 💬 Pilocarpine 3件:  6 , 53, 299 💬
44 Taste transduction 💬
1件: CHRM3 💬 Propantheline bromide 💬 Propantheline 1件: 26 💬
45 Taste transduction 💬
1件: CHRM3 💬 Rocuronium bromide 💬 Rocuronium 2件: 70, 296 💬
46 Taste transduction 💬
1件: CHRM3 💬 Scopolamine 💬 Scopolamine 1件:  2  💬
47 Taste transduction 💬
1件: CHRM3 💬 Solifenacin succinate 💬 Solifenacin 2件:  6 , 13 💬
48 Taste transduction 💬
1件: CHRM3 💬 Solifenacin 💬 Solifenacin 2件:  6 , 13 💬
49 Taste transduction 💬
1件: CHRM3 💬 Tiotropium bromide hydrate 💬 Tiotropium 3件: 55, 85, 299 💬
50 Taste transduction 💬
1件: CHRM3 💬 Tolterodine 💬 Tolterodine 1件: 17 💬
51 Taste transduction 💬
1件: CHRM3 💬 Tolterodine tartrate 💬 Tolterodine 1件: 17 💬
52 Taste transduction 💬
1件: CHRM3 💬 Trihexyphenidyl hydrochloride 💬 Trihexyphenidyl 2件:  5 ,  6  💬
53 Taste transduction 💬
1件: CHRM3 💬 Trihexyphenidyl 💬 Trihexyphenidyl 2件:  5 ,  6  💬
54 Taste transduction 💬
1件: CHRM3 💬 Tropicamide 💬 Tropicamide 1件: 19 💬
55 Taste transduction 💬
2件: GABBR, GABBR 💬 Arbaclofen placarbil 💬 Arbaclofen Placarbil 1件: 13 💬
56 Taste transduction 💬
2件: GABBR, GABBR 💬 Arbaclofen 💬 Arbaclofen 2件: 13, 206 💬
57 Taste transduction 💬
2件: GABBR, GABBR 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
58 Taste transduction 💬
2件: GABBR, GABBR 💬 Valiloxybate 💬 Valiloxibic acid 1件:  6  💬
59 Taste transduction 💬
8件: GABBR, GABBR, GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 gamma-Aminobutyric acid 💬 gamma-Aminobutyric acid 1件: 140 💬
60 Taste transduction 💬
1件: GABRA 💬 Etomidate 💬 Etomidate 2件:  6 , 11 💬
61 Taste transduction 💬
1件: GABRA 💬 Alogabat 💬 Alogabat 1件: 201 💬
62 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Midazolam 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
63 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Zolpidem 💬 Zolpidem 3件:  5 ,  6 , 46 💬
64 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Brexanolone 💬 Brexanolone 2件:  6 , 205 💬
65 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Flumazenil 💬 Flumazenil 5件:  6 , 13, 17, 18, 206 💬
66 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Lorazepam 💬 Lorazepam 2件: 36, 231 💬
67 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Alprazolam 💬 Alprazolam 2件:  8 , 75 💬
68 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Clonazepam 💬 Clonazepam 1件:  6  💬
69 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
70 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
71 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Midazolam hydrochloride 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
72 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Propofol 💬 Propofol 10件:  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬
73 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Zolpidem tartrate 💬 Zolpidem 3件:  5 ,  6 , 46 💬
74 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Clobazam 💬 Clobazam 2件: 140, 144 💬
75 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Fospropofol disodium 💬 Fospropofol 1件: 226 💬
76 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Chlordiazepoxide hydrochloride 💬 Chlordiazepoxide 1件: 46 💬
77 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Remimazolam besylate 💬 Remimazolam 1件:  6  💬
78 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Diazepam 💬 Diazepam 3件: 46, 155, 298 💬
79 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Eszopiclone 💬 Eszopiclone 3件:  6 , 13, 46 💬
80 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Remimazolam 💬 Remimazolam 1件:  6  💬
81 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Chlordiazepoxide 💬 Chlordiazepoxide 1件: 46 💬
82 Taste transduction 💬
6件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA 💬 Midazolam maleate 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
83 Taste transduction 💬
1件: HTR1 💬 Aripiprazole 💬 Aripiprazole 2件:  6 , 206 💬
84 Taste transduction 💬
1件: HTR1 💬 Buspirone hydrochloride 💬 Buspirone 3件:  6 , 51, 179 💬
85 Taste transduction 💬
1件: HTR1 💬 Buspirone 💬 Buspirone 3件:  6 , 51, 179 💬
86 Taste transduction 💬
1件: HTR1 💬 Pardoprunox hydrochloride 💬 Pardoprunox 1件:  6  💬
87 Taste transduction 💬
1件: HTR1 💬 Pardoprunox 💬 Pardoprunox 1件:  6  💬
88 Taste transduction 💬
1件: HTR1 💬 Sarizotan hydrochloride 💬 Sarizotan 2件:  6 , 156 💬
89 Taste transduction 💬
1件: HTR1 💬 Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
90 Taste transduction 💬
1件: HTR1 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
91 Taste transduction 💬
2件: HTR1, HTR1 💬 Zolmitriptan 💬 Zolmitriptan 1件:  6  💬
92 Taste transduction 💬
6件: HTR1, HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine 💬 Vortioxetine 2件:  6 , 127 💬
93 Taste transduction 💬
6件: HTR1, HTR3, HTR3, HTR3, HTR3, HTR3 💬 Vortioxetine hydrobromide 💬 Vortioxetine 2件:  6 , 127 💬
94 Taste transduction 💬
1件: HTR3 💬 Cisapride 💬 Cisapride 1件: 13 💬
95 Taste transduction 💬
1件: HTR3 💬 Cisapride 💬 Cisapride 1件: 13 💬
96 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Clozapine 💬 Clozapine 1件:  6  💬
97 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron hydrochloride hydrate 💬 Ondansetron 5件:  6 , 97, 98, 107, 231 💬
98 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron mesylate 💬 Dolasetron 1件: 46 💬
99 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Mirtazapine 💬 Mirtazapine 3件:  6 , 85, 97 💬
100 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ondansetron 💬 Ondansetron 5件:  6 , 97, 98, 107, 231 💬
101 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron hydrochloride 💬 Ramosetron 1件: 97 💬
102 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Dolasetron 💬 Dolasetron 1件: 46 💬
103 Taste transduction 💬
5件: HTR3, HTR3, HTR3, HTR3, HTR3 💬 Ramosetron 💬 Ramosetron 1件: 97 💬
104 Taste transduction 💬
1件: P2RX3 💬 Gefapixant 💬 Gefapixant 2件: 85, 226 💬
105 Taste transduction 💬
1件: P2RX3 💬 Gefapixant citrate 💬 Gefapixant 2件: 85, 226 💬
106 Taste transduction 💬
1件: PDE1 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
107 Taste transduction 💬
1件: PDE1 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
108 Taste transduction 💬
1件: PDE1 💬 Caffeine citrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
109 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
110 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
111 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
112 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
113 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
114 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
115 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
116 Taste transduction 💬
3件: PDE1, PDE1, PDE1 💬 Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
117 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Amiodarone hydrochloride 💬 Amiodarone 1件: 127 💬
118 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Amiodarone 💬 Amiodarone 1件: 127 💬
119 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Bupivacaine hydrochloride 💬 Bupivacaine 6件: 46, 53, 70, 96, 168, 226 💬
120 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Bupivacaine 💬 Bupivacaine 6件: 46, 53, 70, 96, 168, 226 💬
121 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Carbamazepine 💬 Carbamazepine 3件:  6 , 13, 231 💬
122 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Eleclazine 💬 Eleclazine 1件: 58 💬
123 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Flecainide acetate 💬 Flecainide 2件:  6 , 115 💬
124 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Flecainide 💬 Flecainide 2件:  6 , 115 💬
125 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Lamotrigine 💬 Lamotrigine 6件: 13, 34, 38, 113, 114, 144 💬
126 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Levobupivacaine hydrochloride 💬 Levobupivacaine 1件: 46 💬
127 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Levobupivacaine 💬 Levobupivacaine 1件: 46 💬
128 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Lidocaine 💬 Lidocaine 14件:  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
129 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Lidocaine hydrochloride 💬 Lidocaine 14件:  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
130 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Lidocaine hydrochloride monohydrate 💬 Lidocaine 14件:  6 , 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
131 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Mexiletine hydrochloride 💬 Mexiletine 5件:  1 ,  2 , 10, 113, 114 💬
132 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Mexiletine 💬 Mexiletine 5件:  1 ,  2 , 10, 113, 114 💬
133 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Oxcarbazepine 💬 Oxcarbazepine 1件: 13 💬
134 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Benoxinate hydrochloride 💬 Oxybuprocaine 1件:  6  💬
135 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Oxybuprocaine 💬 Oxybuprocaine 1件:  6  💬
136 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Phenytoin 💬 Phenytoin 1件: 13 💬
137 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Phenytoin sodium 💬 Phenytoin 1件: 13 💬
138 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Quinidine gluconate 💬 Quinidine 2件:  8 , 13 💬
139 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Quinidine polygalacturonate 💬 Quinidine 2件:  8 , 13 💬
140 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Quinidine sulfate 💬 Quinidine 2件:  8 , 13 💬
141 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Quinidine 💬 Quinidine 2件:  8 , 13 💬
142 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Ropivacaine hydrochloride 💬 Ropivacaine 5件: 22, 36, 46, 70, 97 💬
143 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Ropivacaine 💬 Ropivacaine 5件: 22, 36, 46, 70, 97 💬
144 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Rufinamide 💬 Rufinamide 1件: 144 💬
145 Taste transduction 💬
3件: SCN2A, SCN3A, SCN9A 💬 Zonisamide 💬 Zonisamide 1件:  6  💬
146 Taste transduction 💬
2件: SCN3A, SCN9A 💬 Lacosamide 💬 Lacosamide 4件:  2 , 46, 149, 298 💬
147 Taste transduction 💬
3件: SCNN1A, SCNN1B, SCNN1G 💬 Amiloride hydrochloride 💬 Amiloride 4件: 13, 67, 225, 299 💬
148 Taste transduction 💬
3件: SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride 4件: 13, 67, 225, 299 💬