Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Breast cancer 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
2 Breast cancer 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
3 Breast cancer 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
4 Breast cancer 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
5 Breast cancer 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
6 Breast cancer 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
7 Breast cancer 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
8 Breast cancer 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
9 Breast cancer 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
10 Breast cancer 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
11 Breast cancer 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
12 Breast cancer 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
13 Breast cancer 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
14 Breast cancer 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
15 Breast cancer 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
16 Breast cancer 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
17 Breast cancer 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
18 Breast cancer 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
19 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
20 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
21 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
22 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
23 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
24 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
25 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
26 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
27 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
28 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
29 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
30 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
31 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
32 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
33 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
34 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
35 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
36 Chemical carcinogenesis - receptor activation 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
37 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
38 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
39 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
40 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
41 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
42 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
43 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
44 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
45 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
46 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
47 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
48 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
49 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
50 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
51 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
52 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
53 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
54 Endocrine and other factor-regulated calcium reabsorption 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
55 Estrogen signaling pathway 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
56 Estrogen signaling pathway 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
57 Estrogen signaling pathway 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
58 Estrogen signaling pathway 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
59 Estrogen signaling pathway 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
60 Estrogen signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
61 Estrogen signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
62 Estrogen signaling pathway 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
63 Estrogen signaling pathway 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
64 Estrogen signaling pathway 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
65 Estrogen signaling pathway 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
66 Estrogen signaling pathway 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
67 Estrogen signaling pathway 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
68 Estrogen signaling pathway 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
69 Estrogen signaling pathway 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
70 Estrogen signaling pathway 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
71 Estrogen signaling pathway 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
72 Estrogen signaling pathway 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
73 Hormone signaling 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
74 Hormone signaling 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
75 Hormone signaling 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
76 Hormone signaling 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
77 Hormone signaling 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
78 Hormone signaling 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
79 Hormone signaling 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
80 Hormone signaling 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
81 Hormone signaling 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
82 Hormone signaling 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
83 Hormone signaling 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
84 Hormone signaling 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
85 Hormone signaling 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
86 Hormone signaling 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
87 Hormone signaling 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
88 Hormone signaling 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
89 Hormone signaling 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
90 Hormone signaling 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
91 Pathways in cancer 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
92 Pathways in cancer 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
93 Pathways in cancer 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
94 Pathways in cancer 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
95 Pathways in cancer 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
96 Pathways in cancer 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
97 Pathways in cancer 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
98 Pathways in cancer 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
99 Pathways in cancer 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
100 Pathways in cancer 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
101 Pathways in cancer 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
102 Pathways in cancer 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
103 Pathways in cancer 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
104 Pathways in cancer 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
105 Pathways in cancer 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
106 Pathways in cancer 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
107 Pathways in cancer 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
108 Pathways in cancer 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
109 Prolactin signaling pathway 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
110 Prolactin signaling pathway 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
111 Prolactin signaling pathway 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
112 Prolactin signaling pathway 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
113 Prolactin signaling pathway 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
114 Prolactin signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
115 Prolactin signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
116 Prolactin signaling pathway 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
117 Prolactin signaling pathway 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
118 Prolactin signaling pathway 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
119 Prolactin signaling pathway 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
120 Prolactin signaling pathway 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
121 Prolactin signaling pathway 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
122 Prolactin signaling pathway 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
123 Prolactin signaling pathway 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
124 Prolactin signaling pathway 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
125 Prolactin signaling pathway 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
126 Prolactin signaling pathway 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
127 Proteoglycans in cancer 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
128 Proteoglycans in cancer 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
129 Proteoglycans in cancer 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
130 Proteoglycans in cancer 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
131 Proteoglycans in cancer 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
132 Proteoglycans in cancer 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
133 Proteoglycans in cancer 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
134 Proteoglycans in cancer 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
135 Proteoglycans in cancer 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
136 Proteoglycans in cancer 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
137 Proteoglycans in cancer 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
138 Proteoglycans in cancer 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
139 Proteoglycans in cancer 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
140 Proteoglycans in cancer 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
141 Proteoglycans in cancer 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
142 Proteoglycans in cancer 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
143 Proteoglycans in cancer 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
144 Proteoglycans in cancer 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
145 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
146 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
147 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
148 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
149 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
150 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
151 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estetrol 💬 Estetrol 1件: 53 💬
152 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
153 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
154 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estriol 💬 Estriol 2件: 13, 227 💬
155 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
156 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
157 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
158 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
159 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
160 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
161 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
162 Thyroid hormone signaling pathway 💬
1件: ESR1 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬