Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Adipocytokine signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Adipocytokine signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 2 | Adipocytokine signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Adipocytokine signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 3 | Alcoholic liver disease 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Alcoholic liver disease
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 4 | Alcoholic liver disease 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Alcoholic liver disease
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 5 | AMPK signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬AMPK signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 6 | AMPK signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬AMPK signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 7 | Apelin signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Apelin signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 8 | Apelin signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Apelin signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 9 | Autophagy - animal 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Autophagy - animal
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 10 | Autophagy - animal 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Autophagy - animal
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 11 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Circadian rhythm
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 12 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Circadian rhythm
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 13 | Fluid shear stress and atherosclerosis 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Fluid shear stress and atherosclerosis
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 14 | Fluid shear stress and atherosclerosis 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Fluid shear stress and atherosclerosis
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 15 | FoxO signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬FoxO signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 16 | FoxO signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬FoxO signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 17 | Glucagon signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Glucagon signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 18 | Glucagon signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Glucagon signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 19 | Hypertrophic cardiomyopathy 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Hypertrophic cardiomyopathy
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 20 | Hypertrophic cardiomyopathy 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Hypertrophic cardiomyopathy
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 21 | Insulin resistance 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Insulin resistance
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 22 | Insulin resistance 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Insulin resistance
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 23 | Insulin signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Insulin signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 24 | Insulin signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Insulin signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 25 | Longevity regulating pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Longevity regulating pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 26 | Longevity regulating pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Longevity regulating pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 27 | Longevity regulating pathway - multiple species 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Longevity regulating pathway - multiple species
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 28 | Longevity regulating pathway - multiple species 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Longevity regulating pathway - multiple species
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 29 | mTOR signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬mTOR signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 30 | mTOR signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬mTOR signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 31 | Non-alcoholic fatty liver disease 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Non-alcoholic fatty liver disease
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 32 | Non-alcoholic fatty liver disease 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Non-alcoholic fatty liver disease
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 33 | Oxytocin signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Oxytocin signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 34 | Oxytocin signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Oxytocin signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 35 | PI3K-Akt signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬PI3K-Akt signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 36 | PI3K-Akt signaling pathway 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬PI3K-Akt signaling pathway
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 37 | Thermogenesis 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Thermogenesis
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 38 | Thermogenesis 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Thermogenesis
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 39 | Tight junction 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin Metformin 💬Tight junction
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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| 40 | Tight junction 💬 2 genes, 1 drug (DrugBank) and 28 diseases |
PRKAA 2件: PRKAA, PRKAA 💬
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Metformin hydrochloride Metformin hydrochloride 💬Tight junction
| Metformin | 002 28件: 2 , 6 , 8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬1. Adipocytokine signaling pathway
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Adipocytokine signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Alcoholic liver disease
2 genes, 1 drug (DrugBank) and 28 diseases
AMPK signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Apelin signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Autophagy - animal
2 genes, 1 drug (DrugBank) and 28 diseases
Circadian rhythm
2 genes, 1 drug (DrugBank) and 28 diseases
Fluid shear stress and atherosclerosis
2 genes, 1 drug (DrugBank) and 28 diseases
FoxO signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Glucagon signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Hypertrophic cardiomyopathy
2 genes, 1 drug (DrugBank) and 28 diseases
Insulin resistance
2 genes, 1 drug (DrugBank) and 28 diseases
Insulin signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Longevity regulating pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Longevity regulating pathway - multiple species
2 genes, 1 drug (DrugBank) and 28 diseases
mTOR signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Non-alcoholic fatty liver disease
2 genes, 1 drug (DrugBank) and 28 diseases
Oxytocin signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
PI3K-Akt signaling pathway
2 genes, 1 drug (DrugBank) and 28 diseases
Thermogenesis
2 genes, 1 drug (DrugBank) and 28 diseases
Tight junction
2 genes, 1 drug (DrugBank) and 28 diseases