Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Adherens junction 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
2 Adherens junction 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
3 Adherens junction 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
4 Adherens junction 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
5 Axon guidance 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
6 Axon guidance 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
7 Axon guidance 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
8 Axon guidance 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
9 cAMP signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
10 cAMP signaling pathway 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
11 cAMP signaling pathway 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
12 cAMP signaling pathway 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
13 cGMP-PKG signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
14 cGMP-PKG signaling pathway 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
15 cGMP-PKG signaling pathway 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
16 cGMP-PKG signaling pathway 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
17 Chemokine signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
18 Chemokine signaling pathway 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
19 Chemokine signaling pathway 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
20 Chemokine signaling pathway 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
21 Focal adhesion 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
22 Focal adhesion 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
23 Focal adhesion 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
24 Focal adhesion 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
25 Human cytomegalovirus infection 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
26 Human cytomegalovirus infection 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
27 Human cytomegalovirus infection 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
28 Human cytomegalovirus infection 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
29 Leukocyte transendothelial migration 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
30 Leukocyte transendothelial migration 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
31 Leukocyte transendothelial migration 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
32 Leukocyte transendothelial migration 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
33 Lipid and atherosclerosis 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
34 Lipid and atherosclerosis 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
35 Lipid and atherosclerosis 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
36 Lipid and atherosclerosis 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
37 Oxytocin signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
38 Oxytocin signaling pathway 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
39 Oxytocin signaling pathway 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
40 Oxytocin signaling pathway 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
41 Pathogenic Escherichia coli infection 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
42 Pathogenic Escherichia coli infection 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
43 Pathogenic Escherichia coli infection 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
44 Pathogenic Escherichia coli infection 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
45 Pathways in cancer 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
46 Pathways in cancer 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
47 Pathways in cancer 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
48 Pathways in cancer 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
49 Platelet activation 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
50 Platelet activation 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
51 Platelet activation 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
52 Platelet activation 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
53 Proteoglycans in cancer 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
54 Proteoglycans in cancer 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
55 Proteoglycans in cancer 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
56 Proteoglycans in cancer 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
57 Regulation of actin cytoskeleton 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
58 Regulation of actin cytoskeleton 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
59 Regulation of actin cytoskeleton 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
60 Regulation of actin cytoskeleton 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
61 Salmonella infection 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
62 Salmonella infection 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
63 Salmonella infection 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
64 Salmonella infection 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
65 Shigellosis 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
66 Shigellosis 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
67 Shigellosis 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
68 Shigellosis 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
69 Sphingolipid signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
70 Sphingolipid signaling pathway 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
71 Sphingolipid signaling pathway 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
72 Sphingolipid signaling pathway 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
73 Tight junction 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
74 Tight junction 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
75 Tight junction 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
76 Tight junction 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
77 Vascular smooth muscle contraction 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
78 Vascular smooth muscle contraction 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
79 Vascular smooth muscle contraction 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
80 Vascular smooth muscle contraction 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
81 Wnt signaling pathway 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
82 Wnt signaling pathway 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
83 Wnt signaling pathway 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
84 Wnt signaling pathway 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
85 Yersinia infection 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
86 Yersinia infection 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
87 Yersinia infection 💬
1件: ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
88 Yersinia infection 💬
1件: ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬