Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Drug metabolism - other enzymes 💬
1件: GUSB 💬 Vestronidase alfa 💬 Vestronidase alfa 1件: 19 💬
2 Drug metabolism - other enzymes 💬
1件: HPRT1 💬 Mercaptopurine 💬 Mercaptopurine 4件: 65, 96, 97, 164 💬
3 Drug metabolism - other enzymes 💬
1件: HPRT1 💬 Mercaptopurine 💬 Mercaptopurine 4件: 65, 96, 97, 164 💬
4 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mizoribine 💬 Mizoribine 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
5 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mycophenolate mofetil 💬 Mycophenolate mofetil 38件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
6 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil 38件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 57, 60, 61, 62, 63, 65, 66, 93, 95, 96, 118, 162, 164, 222, 223, 224, 226, 234, 283, 284, 285, 300 💬
7 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mycophenolate sodium 💬 Mycophenolic acid 11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
8 Drug metabolism - other enzymes 💬
2件: IMPDH1, IMPDH2 💬 Mycophenolic acid 💬 Mycophenolic acid 11件: 11, 43, 49, 51, 53, 60, 66, 96, 222, 223, 228 💬
9 Drug metabolism - other enzymes 💬
1件: MPO 💬 Verdiperstat 💬 Verdiperstat 3件:  2 , 17, 127 💬
10 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Cladribine 💬 Cladribine 3件: 11, 13, 94 💬
11 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Clofarabine 💬 Clofarabine 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬
12 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Fludarabine phosphate 💬 Fludarabine 30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
13 Drug metabolism - other enzymes 💬
1件: RRM1 💬 Fludarabine 💬 Fludarabine 30件: 11, 13, 14, 16, 19, 28, 34, 35, 36, 44, 46, 49, 50, 51, 60, 61, 62, 63, 65, 85, 96, 107, 164, 222, 223, 283, 284, 285, 286, 326 💬
14 Drug metabolism - other enzymes 💬
1件: RRM2 💬 Hydroxyurea 💬 Hydroxyurea 10件:  3 , 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
15 Drug metabolism - other enzymes 💬
1件: TK2 💬 Doxribtimine 💬 Thymidine 2件: 215, 216 💬
16 Drug metabolism - other enzymes 💬
1件: XDH 💬 Allopurinol 💬 Allopurinol 7件:  6 , 46, 57, 60, 66, 96, 97 💬
17 Drug metabolism - other enzymes 💬
1件: XDH 💬 Allopurinol sodium 💬 Allopurinol 7件:  6 , 46, 57, 60, 66, 96, 97 💬
18 Drug metabolism - other enzymes 💬
1件: XDH 💬 Febuxostat 💬 Febuxostat 5件:  2 ,  6 , 13, 67, 97 💬
19 Drug metabolism - other enzymes 💬
1件: XDH 💬 Febuxostat hydrate 💬 Febuxostat 5件:  2 ,  6 , 13, 67, 97 💬