Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 FoxO signaling pathway 💬
 1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
2 FoxO signaling pathway 💬
 1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
3 FoxO signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
4 FoxO signaling pathway 💬
 2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
5 FoxO signaling pathway 💬
 1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
6 FoxO signaling pathway 💬
 1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
7 FoxO signaling pathway 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
8 FoxO signaling pathway 💬
 1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
9 FoxO signaling pathway 💬
 1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
10 FoxO signaling pathway 💬
 1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
11 FoxO signaling pathway 💬
 1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
12 FoxO signaling pathway 💬
 1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
13 FoxO signaling pathway 💬
 1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
14 FoxO signaling pathway 💬
 1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
15 FoxO signaling pathway 💬
 1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
16 FoxO signaling pathway 💬
 1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
17 FoxO signaling pathway 💬
 1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
18 FoxO signaling pathway 💬
 1件: IGF1R 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
19 FoxO signaling pathway 💬
 1件: IGF1R 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
20 FoxO signaling pathway 💬
 2件: IL10, IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
21 FoxO signaling pathway 💬
 1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
22 FoxO signaling pathway 💬
 1件: IL6 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
23 FoxO signaling pathway 💬
 1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
24 FoxO signaling pathway 💬
 1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
25 FoxO signaling pathway 💬
 1件: IL7R 💬 Lusvertikimab 💬 Lusvertikimab 1件: 97 💬
26 FoxO signaling pathway 💬
 1件: INSR 💬 Insulin detemir 💬 Insulin detemir 1件: 299 💬
27 FoxO signaling pathway 💬
 1件: INSR 💬 Insulin glargine 💬 Insulin glargine 1件: 299 💬
28 FoxO signaling pathway 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 1件: 156 💬
29 FoxO signaling pathway 💬
 1件: INSR 💬 Insulin lispro 💬 Insulin lispro 1件: 53 💬
30 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
31 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
32 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
33 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
34 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
35 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
36 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
37 FoxO signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
38 FoxO signaling pathway 💬
 4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
39 FoxO signaling pathway 💬
 4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
40 FoxO signaling pathway 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
41 FoxO signaling pathway 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
42 FoxO signaling pathway 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
43 FoxO signaling pathway 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
44 FoxO signaling pathway 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
45 FoxO signaling pathway 💬
 1件: PLK1 💬 Rigosertib 💬 Rigosertib 1件: 36 💬
46 FoxO signaling pathway 💬
 1件: PLK1 💬 Rigosertib sodium 💬 Rigosertib 1件: 36 💬
47 FoxO signaling pathway 💬
 2件: PRKAA, PRKAA 💬 Metformin hydrochloride 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
48 FoxO signaling pathway 💬
 2件: PRKAA, PRKAA 💬 Metformin 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
49 FoxO signaling pathway 💬
 1件: S1PR1 💬 Cenerimod 💬 Cenerimod 1件: 49 💬
50 FoxO signaling pathway 💬
 1件: S1PR1 💬 Fingolimod hydrochloride 💬 Fingolimod 3件: 13, 14, 156 💬
51 FoxO signaling pathway 💬
 1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
52 FoxO signaling pathway 💬
 1件: S1PR1 💬 Fingolimod lauryl sulfate 💬 Fingolimod 3件: 13, 14, 156 💬
53 FoxO signaling pathway 💬
 1件: S1PR1 💬 Ponesimod 💬 Ponesimod 1件: 13 💬
54 FoxO signaling pathway 💬
 1件: S1PR1 💬 Siponimod fumarate 💬 Siponimod 2件: 13, 50 💬
55 FoxO signaling pathway 💬
 1件: S1PR1 💬 Siponimod 💬 Siponimod 2件: 13, 50 💬
56 FoxO signaling pathway 💬
 2件: S1PR1, S1PR4 💬 Amiselimod 💬 Amiselimod 1件: 97 💬
57 FoxO signaling pathway 💬
 2件: S1PR1, S1PR4 💬 Etrasimod 💬 Etrasimod 3件: 96, 97, 98 💬
58 FoxO signaling pathway 💬
 2件: S1PR1, S1PR4 💬 Etrasimod arginine 💬 Etrasimod 3件: 96, 97, 98 💬
59 FoxO signaling pathway 💬
 2件: S1PR1, S1PR4 💬 Ozanimod hydrochloride 💬 Ozanimod 3件: 13, 96, 97 💬
60 FoxO signaling pathway 💬
 2件: S1PR1, S1PR4 💬 Ozanimod 💬 Ozanimod 3件: 13, 96, 97 💬
61 FoxO signaling pathway 💬
 3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬