Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ACVR1 1件: ACVR1 💬
|
Fidrisertib Fidrisertib 💬
| Fidrisertib | 272 1件: 272 💬
|
| 2 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ACVR1 1件: ACVR1 💬
|
Zilurgisertib Zilurgisertib 💬
| Zilurgisertib | 272 1件: 272 💬
|
| 3 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ACVR2A 1件: ACVR2A 💬
|
Sotatercept Sotatercept 💬
| Sotatercept | 086 2件: 86, 284 💬
|
| 4 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ACVR2A 2件: ACVR2A, ACVR2B 💬
|
Bimagrumab Bimagrumab 💬
| Bimagrumab | 015 1件: 15 💬
|
| 5 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ACVR2B 1件: ACVR2B 💬
|
Luspatercept Luspatercept 💬
| Luspatercept | 060 3件: 60, 61, 282 💬
|
| 6 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
HDAC1_2 2件: HDAC1_2, HDAC1_2 💬
|
Fimepinostat Fimepinostat 💬
| Fimepinostat | 075 1件: 75 💬
|
| 7 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
HDAC1_2 2件: HDAC1_2, HDAC1_2 💬
|
Vorinostat Vorinostat 💬
| Vorinostat | 075 2件: 75, 96 💬
|
| 8 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
HDAC1_2 2件: HDAC1_2, HDAC1_2 💬
|
Givinostat Givinostat 💬
| Givinostat | 107 2件: 107, 113 💬
|
| 9 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
IFNG 1件: IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 5件: 49, 54, 60, 65, 107 💬
|
| 10 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
IFNG 1件: IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 1件: 46 💬
|
| 11 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
RGMA 1件: RGMA 💬
|
Elezanumab Elezanumab 💬
| Elezanumab | 013 1件: 13 💬
|
| 12 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ROCK1 1件: ROCK1 💬
|
Fasudil hydrochloride Fasudil hydrochloride 💬
| Fasudil | 002 5件: 2 , 5 , 6 , 7 , 51 💬
|
| 13 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
ROCK1 1件: ROCK1 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 5件: 2 , 5 , 6 , 7 , 51 💬
|
| 14 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
SMAD7 1件: SMAD7 💬
|
Mongersen Mongersen 💬
| Mongersen | 096 2件: 96, 97 💬
|
| 15 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TFRC 1件: TFRC 💬
|
Pabinafusp alfa Pabinafusp alfa 💬
| Pabinafusp alfa | 019 1件: 19 💬
|
| 16 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TFRC 1件: TFRC 💬
|
Tividenofusp alfa Tividenofusp alfa 💬
| Tividenofusp alfa | 019 1件: 19 💬
|
| 17 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 4件: 51, 85, 222, 274 💬
|
| 18 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
|
| 19 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 7件: 37, 46, 49, 96, 107, 226, 271 💬
|
| 20 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
|
| 21 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 22 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
|
| 23 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 24 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 1件: 46 💬
|
| 25 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 1件: 46 💬
|
| 26 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 27 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬
|
| 28 | TGF-beta signaling pathway 💬 14 genes, 27 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 21件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
|