Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Complement and coagulation cascades 💬
1件: BDKRB2 💬 Deucrictibant 💬 Deucrictibant 1件: 65 💬
2 Complement and coagulation cascades 💬
1件: BDKRB2 💬 Icatibant acetate 💬 Icatibant 1件: 65 💬
3 Complement and coagulation cascades 💬
3件: C1R, C1S, KLKB1 💬 Conestat alfa 💬 Conestat alfa 2件: 61, 65 💬
4 Complement and coagulation cascades 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
5 Complement and coagulation cascades 💬
1件: C1S 💬 Sutimlimab 💬 Sutimlimab 1件: 61 💬
6 Complement and coagulation cascades 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
7 Complement and coagulation cascades 💬
1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬
8 Complement and coagulation cascades 💬
1件: C5 💬 Avacincaptad pegol sodium 💬 Avacincaptad pegol 1件: 301 💬
9 Complement and coagulation cascades 💬
1件: C5 💬 Crovalimab 💬 Crovalimab 2件: 62, 109 💬
10 Complement and coagulation cascades 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
11 Complement and coagulation cascades 💬
1件: C5 💬 Gefurulimab 💬 Gefurulimab 1件: 11 💬
12 Complement and coagulation cascades 💬
1件: C5 💬 Nomacopan 💬 Nomacopan 3件: 62, 109, 162 💬
13 Complement and coagulation cascades 💬
1件: C5 💬 Pozelimab 💬 Pozelimab 3件: 11, 15, 62 💬
14 Complement and coagulation cascades 💬
1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬
15 Complement and coagulation cascades 💬
1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬
16 Complement and coagulation cascades 💬
1件: C5 💬 Zilucoplan sodium 💬 Zilucoplan 2件: 11, 62 💬
17 Complement and coagulation cascades 💬
1件: C5 💬 Zilucoplan 💬 Zilucoplan 2件: 11, 62 💬
18 Complement and coagulation cascades 💬
1件: C5AR1 💬 Avacopan 💬 Avacopan 4件: 43, 44, 66, 222 💬
19 Complement and coagulation cascades 💬
1件: CFB 💬 Iptacopan 💬 Iptacopan 6件: 11, 61, 62, 66, 109, 222 💬
20 Complement and coagulation cascades 💬
1件: CFB 💬 Iptacopan hydrochloride 💬 Iptacopan 6件: 11, 61, 62, 66, 109, 222 💬
21 Complement and coagulation cascades 💬
1件: CFD 💬 Danicopan 💬 Danicopan 2件: 62, 222 💬
22 Complement and coagulation cascades 💬
1件: F10 💬 Apixaban 💬 Apixaban 4件: 96, 97, 222, 279 💬
23 Complement and coagulation cascades 💬
1件: F10 💬 Edoxaban tosilate hydrate 💬 Edoxaban 2件: 46, 88 💬
24 Complement and coagulation cascades 💬
1件: F10 💬 Edoxaban 💬 Edoxaban 2件: 46, 88 💬
25 Complement and coagulation cascades 💬
1件: F10 💬 Edoxaban tosylate 💬 Edoxaban 2件: 46, 88 💬
26 Complement and coagulation cascades 💬
1件: F10 💬 Rivaroxaban 💬 Rivaroxaban 6件: 46, 49, 56, 91, 210, 271 💬
27 Complement and coagulation cascades 💬
2件: F10, F9 💬 Emicizumab 💬 Emicizumab 1件: 288 💬
28 Complement and coagulation cascades 💬
1件: F12 💬 Garadacimab 💬 Garadacimab 1件: 65 💬
29 Complement and coagulation cascades 💬
1件: F2 💬 Dabigatran 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬
30 Complement and coagulation cascades 💬
1件: F2 💬 Dabigatran etexilate mesylate 💬 Dabigatran etexilate 2件: 51, 75 💬
31 Complement and coagulation cascades 💬
1件: F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate 2件: 51, 75 💬
32 Complement and coagulation cascades 💬
1件: F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa 1件: 85 💬
33 Complement and coagulation cascades 💬
1件: F7 💬 Eptacog alfa 💬 Coagulation factor VIIa Recombinant Human 1件: 288 💬
34 Complement and coagulation cascades 💬
1件: F8 💬 Octocog alfa 💬 Antihemophilic factor, human recombinant 1件: 288 💬
35 Complement and coagulation cascades 💬
1件: F8 💬 Desmopressin 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
36 Complement and coagulation cascades 💬
1件: F8 💬 Desmopressin acetate 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
37 Complement and coagulation cascades 💬
1件: F8 💬 Efanesoctocog alfa 💬 Efanesoctocog alfa 1件: 288 💬
38 Complement and coagulation cascades 💬
1件: F8 💬 Rurioctocog alfa pegol 💬 Rurioctocog alfa pegol 1件: 288 💬
39 Complement and coagulation cascades 💬
1件: F8 💬 Susoctocog alfa 💬 Susoctocog alfa 1件: 288 💬
40 Complement and coagulation cascades 💬
1件: KLKB1 💬 Berotralstat 💬 Berotralstat 1件: 65 💬
41 Complement and coagulation cascades 💬
1件: KLKB1 💬 Berotralstat hydrochloride 💬 Berotralstat 1件: 65 💬
42 Complement and coagulation cascades 💬
1件: KLKB1 💬 Ecallantide 💬 Ecallantide 1件: 65 💬
43 Complement and coagulation cascades 💬
1件: KLKB1 💬 Lanadelumab 💬 Lanadelumab 1件: 65 💬
44 Complement and coagulation cascades 💬
1件: KLKB1 💬 Sebetralstat 💬 Sebetralstat 1件: 65 💬
45 Complement and coagulation cascades 💬
1件: MASP2 💬 Narsoplimab 💬 Narsoplimab 2件: 66, 222 💬
46 Complement and coagulation cascades 💬
2件: PLAT, PLG 💬 Aminocaproic acid 💬 Aminocaproic acid 1件: 70 💬
47 Complement and coagulation cascades 💬
1件: PLG 💬 Tranexamic acid 💬 Tranexamic acid 8件: 46, 65, 70, 215, 227, 274, 288, 299 💬
48 Complement and coagulation cascades 💬
1件: SERPINA1 💬 alpha 1-Antitrypsin 💬 Alpha-1-proteinase inhibitor 3件: 231, 298, 299 💬
49 Complement and coagulation cascades 💬
1件: SERPINC1 💬 Dalteparin sodium 💬 Dalteparin 1件: 222 💬
50 Complement and coagulation cascades 💬
1件: SERPINC1 💬 Enoxaparin sodium 💬 Enoxaparin 1件: 46 💬
51 Complement and coagulation cascades 💬
1件: SERPINC1 💬 Adomiparin 💬 Enoxaparin 1件: 46 💬
52 Complement and coagulation cascades 💬
1件: SERPINC1 💬 Heparin sodium 💬 Heparin 10件: 47, 60, 65, 70, 79, 84, 107, 226, 280, 299 💬
53 Complement and coagulation cascades 💬
1件: SERPINC1 💬 Heparin calcium 💬 Heparin 10件: 47, 60, 65, 70, 79, 84, 107, 226, 280, 299 💬
54 Complement and coagulation cascades 💬
1件: VWF 💬 Caplacizumab 💬 Caplacizumab 2件: 63, 64 💬