Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 IL-17 signaling pathway 💬
4件: CCL2, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
2 IL-17 signaling pathway 💬
1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
3 IL-17 signaling pathway 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
4 IL-17 signaling pathway 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
5 IL-17 signaling pathway 💬
1件: IL13 💬 Anrukinzumab 💬 Anrukinzumab 1件: 97 💬
6 IL-17 signaling pathway 💬
1件: IL13 💬 Cendakimab 💬 Cendakimab 1件: 98 💬
7 IL-17 signaling pathway 💬
1件: IL13 💬 Lebrikizumab 💬 Lebrikizumab 1件: 85 💬
8 IL-17 signaling pathway 💬
1件: IL13 💬 Tralokinumab 💬 Tralokinumab 2件: 85, 97 💬
9 IL-17 signaling pathway 💬
1件: IL17A 💬 Ixekizumab 💬 Ixekizumab 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬
10 IL-17 signaling pathway 💬
1件: IL17A 💬 Secukinumab 💬 Secukinumab 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
11 IL-17 signaling pathway 💬
1件: IL17A 💬 Tibulizumab 💬 Tibulizumab 2件: 51, 53 💬
12 IL-17 signaling pathway 💬
2件: IL17A, IL17F 💬 Bimekizumab 💬 Bimekizumab 5件: 37, 46, 97, 107, 271 💬
13 IL-17 signaling pathway 💬
1件: IL17RA 💬 Brodalumab 💬 Brodalumab 2件: 37, 51 💬
14 IL-17 signaling pathway 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
15 IL-17 signaling pathway 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
16 IL-17 signaling pathway 💬
1件: IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
17 IL-17 signaling pathway 💬
1件: IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
18 IL-17 signaling pathway 💬
1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
19 IL-17 signaling pathway 💬
1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
20 IL-17 signaling pathway 💬
1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
21 IL-17 signaling pathway 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
22 IL-17 signaling pathway 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
23 IL-17 signaling pathway 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
24 IL-17 signaling pathway 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
25 IL-17 signaling pathway 💬
1件: MMP13 💬 Apratastat 💬 Apratastat 1件: 46 💬
26 IL-17 signaling pathway 💬
1件: MMP9 💬 Andecaliximab 💬 Andecaliximab 5件: 46, 96, 97, 272, 299 💬
27 IL-17 signaling pathway 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
28 IL-17 signaling pathway 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
29 IL-17 signaling pathway 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
30 IL-17 signaling pathway 💬
1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
31 IL-17 signaling pathway 💬
1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
32 IL-17 signaling pathway 💬
1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
33 IL-17 signaling pathway 💬
1件: PTGS2 💬 Celecoxib 💬 Celecoxib 14件:  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
34 IL-17 signaling pathway 💬
1件: PTGS2 💬 Diclofenac potassium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
35 IL-17 signaling pathway 💬
1件: PTGS2 💬 Diclofenac sodium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
36 IL-17 signaling pathway 💬
1件: PTGS2 💬 Diclofenac 💬 Diclofenac 4件: 13, 34, 46, 271 💬
37 IL-17 signaling pathway 💬
1件: PTGS2 💬 Diclofenac diethylamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
38 IL-17 signaling pathway 💬
1件: PTGS2 💬 Diclofenac epolamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
39 IL-17 signaling pathway 💬
1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
40 IL-17 signaling pathway 💬
1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 3件: 46, 70, 271 💬
41 IL-17 signaling pathway 💬
1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
42 IL-17 signaling pathway 💬
1件: PTGS2 💬 Flurbiprofen sodium 💬 Flurbiprofen 3件: 13, 21, 46 💬
43 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
44 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ibuprofen aluminum 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
45 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ibuprofen lysine 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
46 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
47 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
48 IL-17 signaling pathway 💬
1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
49 IL-17 signaling pathway 💬
1件: PTGS2 💬 Indomethacin sodium 💬 Indomethacin 3件: 225, 271, 298 💬
50 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 2件: 13, 46 💬
51 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ketoprofen lysine 💬 Ketoprofen 2件: 13, 46 💬
52 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ketoprofen sodium 💬 Ketoprofen 2件: 13, 46 💬
53 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ketorolac tromethamine 💬 Ketorolac 2件: 70, 226 💬
54 IL-17 signaling pathway 💬
1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
55 IL-17 signaling pathway 💬
1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
56 IL-17 signaling pathway 💬
1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
57 IL-17 signaling pathway 💬
1件: PTGS2 💬 Meloxicam 💬 Meloxicam 3件: 46, 271, 296 💬
58 IL-17 signaling pathway 💬
1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
59 IL-17 signaling pathway 💬
1件: PTGS2 💬 Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
60 IL-17 signaling pathway 💬
1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
61 IL-17 signaling pathway 💬
1件: PTGS2 💬 Valdecoxib 💬 Parecoxib 2件: 46, 271 💬
62 IL-17 signaling pathway 💬
1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
63 IL-17 signaling pathway 💬
1件: PTGS2 💬 Parecoxib sodium 💬 Parecoxib 2件: 46, 271 💬
64 IL-17 signaling pathway 💬
1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
65 IL-17 signaling pathway 💬
1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
66 IL-17 signaling pathway 💬
1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
67 IL-17 signaling pathway 💬
1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
68 IL-17 signaling pathway 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
69 IL-17 signaling pathway 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
70 IL-17 signaling pathway 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
71 IL-17 signaling pathway 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
72 IL-17 signaling pathway 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
73 IL-17 signaling pathway 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
74 IL-17 signaling pathway 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
75 IL-17 signaling pathway 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
76 IL-17 signaling pathway 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
77 IL-17 signaling pathway 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬