Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
2 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 Muromonab-CD3 💬 Muromonab 3件: 60, 96, 97 💬
3 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
4 Th1 and Th2 cell differentiation 💬
3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
5 Th1 and Th2 cell differentiation 💬
5件: CD3D, CD3E, CD3G, CD4, IL2RA 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
6 Th1 and Th2 cell differentiation 💬
1件: CD3E 💬 Elranatamab 💬 Elranatamab 1件: 28 💬
7 Th1 and Th2 cell differentiation 💬
1件: CD3E 💬 Imvotamab 💬 Imvotamab 2件: 46, 49 💬
8 Th1 and Th2 cell differentiation 💬
1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
9 Th1 and Th2 cell differentiation 💬
1件: CD3E 💬 Talquetamab 💬 Talquetamab 1件: 28 💬
10 Th1 and Th2 cell differentiation 💬
1件: CD3E 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
11 Th1 and Th2 cell differentiation 💬
1件: CD4 💬 Zanolimumab 💬 Zanolimumab 1件: 46 💬
12 Th1 and Th2 cell differentiation 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
13 Th1 and Th2 cell differentiation 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
14 Th1 and Th2 cell differentiation 💬
2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
15 Th1 and Th2 cell differentiation 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
16 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 Anrukinzumab 💬 Anrukinzumab 1件: 97 💬
17 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 Cendakimab 💬 Cendakimab 1件: 98 💬
18 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 Lebrikizumab 💬 Lebrikizumab 1件: 85 💬
19 Th1 and Th2 cell differentiation 💬
1件: IL13 💬 Tralokinumab 💬 Tralokinumab 2件: 85, 97 💬
20 Th1 and Th2 cell differentiation 💬
1件: IL2RA 💬 Basiliximab 💬 Basiliximab 5件:  2 , 50, 97, 222, 228 💬
21 Th1 and Th2 cell differentiation 💬
1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
22 Th1 and Th2 cell differentiation 💬
3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
23 Th1 and Th2 cell differentiation 💬
1件: IL4R 💬 Dupilumab 💬 Dupilumab 5件: 51, 97, 98, 160, 162 💬
24 Th1 and Th2 cell differentiation 💬
1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
25 Th1 and Th2 cell differentiation 💬
1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
26 Th1 and Th2 cell differentiation 💬
1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
27 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
28 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
29 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
30 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
31 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
32 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
33 Th1 and Th2 cell differentiation 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
34 Th1 and Th2 cell differentiation 💬
2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
35 Th1 and Th2 cell differentiation 💬
2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
36 Th1 and Th2 cell differentiation 💬
2件: JAK1, JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
37 Th1 and Th2 cell differentiation 💬
3件: JAK1, JAK2, JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
38 Th1 and Th2 cell differentiation 💬
3件: JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
39 Th1 and Th2 cell differentiation 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
40 Th1 and Th2 cell differentiation 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
41 Th1 and Th2 cell differentiation 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
42 Th1 and Th2 cell differentiation 💬
4件: JAK1, JAK2, JAK3, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
43 Th1 and Th2 cell differentiation 💬
1件: JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
44 Th1 and Th2 cell differentiation 💬
1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
45 Th1 and Th2 cell differentiation 💬
1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
46 Th1 and Th2 cell differentiation 💬
1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
47 Th1 and Th2 cell differentiation 💬
14件: MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
48 Th1 and Th2 cell differentiation 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
49 Th1 and Th2 cell differentiation 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
50 Th1 and Th2 cell differentiation 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
51 Th1 and Th2 cell differentiation 💬
5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
52 Th1 and Th2 cell differentiation 💬
5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬
53 Th1 and Th2 cell differentiation 💬
5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬
54 Th1 and Th2 cell differentiation 💬
5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
55 Th1 and Th2 cell differentiation 💬
5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Cyclosporine 💬 Cyclosporine 42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
56 Th1 and Th2 cell differentiation 💬
1件: PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
57 Th1 and Th2 cell differentiation 💬
1件: PRKCQ 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
58 Th1 and Th2 cell differentiation 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
59 Th1 and Th2 cell differentiation 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
60 Th1 and Th2 cell differentiation 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬