Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
CXCR4 1件: CXCR4 💬
|
Mavorixafor Mavorixafor 💬
| Mavorixafor | 065 1件: 65 💬
|
2 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
CXCR4 1件: CXCR4 💬
|
Plerixafor Plerixafor 💬
| Plerixafor | 020 5件: 20, 51, 65, 285, 299 💬
|
3 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ICAM1 1件: ICAM1 💬
|
Alicaforsen sodium Alicaforsen sodium 💬
| Alicaforsen | 096 2件: 96, 97 💬
|
4 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬
|
Abrilumab Abrilumab 💬
| Abrilumab | 096 2件: 96, 97 💬
|
5 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬
|
Firategrast Firategrast 💬
| Firategrast | 013 1件: 13 💬
|
6 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬
|
Natalizumab Natalizumab 💬
| Natalizumab | 013 5件: 13, 15, 25, 46, 96 💬
|
7 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGA4 1件: ITGA4 💬
|
Vedolizumab Vedolizumab 💬
| Vedolizumab | 094 3件: 94, 96, 97 💬
|
8 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGA4 2件: ITGA4, ITGB1 💬
|
Carotegrast methyl Carotegrast methyl 💬
| Carotegrast methyl | 097 1件: 97 💬
|
9 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGAL 1件: ITGAL 💬
|
Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit 💬
| Antithymocyte immunoglobulin (rabbit) | 013 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
|
10 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGAL 1件: ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 9件: 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
|
11 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITGB1 1件: ITGB1 💬
|
Bexotegrast Bexotegrast 💬
| Bexotegrast | 094 1件: 94 💬
|
12 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ITK 1件: ITK 💬
|
Soquelitinib Soquelitinib 💬
| Soquelitinib | 065 1件: 65 💬
|
13 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
MMP9 1件: MMP9 💬
|
Andecaliximab Andecaliximab 💬
| Andecaliximab | 046 5件: 46, 96, 97, 272, 299 💬
|
14 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
MYL2 1件: MYL2 💬
|
Aficamten Aficamten 💬
| Aficamten | 058 1件: 58 💬
|
15 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
P38 4件: P38, P38, P38, P38 💬
|
Neflamapimod Neflamapimod 💬
| Neflamapimod | 008 1件: 8 💬
|
16 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
P38 4件: P38, P38, P38, P38 💬
|
Losmapimod Losmapimod 💬
| Losmapimod | 113 2件: 113, 222 💬
|
17 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PIK3CA_B_D 1件: PIK3CA_B_D 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 4件: 138, 278, 279, 280 💬
|
18 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PIK3CA_B_D 1件: PIK3CA_B_D 💬
|
Leniolisib phosphate Leniolisib phosphate 💬
| Leniolisib | 053 2件: 53, 65 💬
|
19 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PIK3CA_B_D 1件: PIK3CA_B_D 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
20 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PIK3CA_B_D 2件: PIK3CA_B_D, PIK3CA_B_D 💬
|
Copanlisib Copanlisib 💬
| Copanlisib | 121 1件: 121 💬
|
21 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PIK3CA_B_D 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
22 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PRKCB 1件: PRKCB 💬
|
Enzastaurin hydrochloride Enzastaurin hydrochloride 💬
| Enzastaurin | 168 1件: 168 💬
|
23 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
PRKCB 1件: PRKCB 💬
|
Enzastaurin Enzastaurin 💬
| Enzastaurin | 168 1件: 168 💬
|
24 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ROCK1 2件: ROCK1, ROCK2 💬
|
Fasudil hydrochloride Fasudil hydrochloride 💬
| Fasudil | 002 5件: 2 , 5 , 6 , 7 , 51 💬
|
25 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ROCK1 2件: ROCK1, ROCK2 💬
|
Fasudil Fasudil 💬
| Fasudil | 002 5件: 2 , 5 , 6 , 7 , 51 💬
|
26 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ROCK2 1件: ROCK2 💬
|
Belumosudil Belumosudil 💬
| Belumosudil | 051 3件: 51, 85, 228 💬
|
27 | Leukocyte transendothelial migration 💬 18 genes, 23 drugs (DrugBank) and 44 diseases |
ROCK2 1件: ROCK2 💬
|
Belumosudil mesylate Belumosudil mesylate 💬
| Belumosudil | 051 3件: 51, 85, 228 💬
|