Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Intestinal immune network for IgA production 💬
2件: CD28, ICOS 💬 Acazicolcept 💬 Acazicolcept 1件: 49 💬
2 Intestinal immune network for IgA production 💬
2件: CD80, CD86 💬 Abatacept 💬 Abatacept 27件:  2 , 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
3 Intestinal immune network for IgA production 💬
2件: CD80, CD86 💬 Belatacept 💬 Belatacept 1件: 46 💬
4 Intestinal immune network for IgA production 💬
1件: CXCR4 💬 Mavorixafor 💬 Mavorixafor 1件: 65 💬
5 Intestinal immune network for IgA production 💬
1件: CXCR4 💬 Plerixafor 💬 Plerixafor 5件: 20, 51, 65, 285, 299 💬
6 Intestinal immune network for IgA production 💬
2件: ICOSLG, TNFSF13B 💬 Rozibafusp alfa 💬 Rozibafusp Alfa 2件: 46, 49 💬
7 Intestinal immune network for IgA production 💬
2件: IL10, IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
8 Intestinal immune network for IgA production 💬
1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
9 Intestinal immune network for IgA production 💬
1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
10 Intestinal immune network for IgA production 💬
1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
11 Intestinal immune network for IgA production 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
12 Intestinal immune network for IgA production 💬
1件: IL6 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
13 Intestinal immune network for IgA production 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
14 Intestinal immune network for IgA production 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
15 Intestinal immune network for IgA production 💬
1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬
16 Intestinal immune network for IgA production 💬
1件: ITGA4 💬 Natalizumab 💬 Natalizumab 5件: 13, 15, 25, 46, 96 💬
17 Intestinal immune network for IgA production 💬
2件: ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬
18 Intestinal immune network for IgA production 💬
2件: ITGA4, ITGB7 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
19 Intestinal immune network for IgA production 💬
2件: ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬
20 Intestinal immune network for IgA production 💬
1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬
21 Intestinal immune network for IgA production 💬
14件: MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
22 Intestinal immune network for IgA production 💬
1件: TGFB1 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
23 Intestinal immune network for IgA production 💬
1件: TNFRSF13B 💬 Povetacicept 💬 Povetacicept 3件: 61, 63, 222 💬
24 Intestinal immune network for IgA production 💬
1件: TNFRSF13C 💬 Ianalumab 💬 Ianalumab 8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
25 Intestinal immune network for IgA production 💬
1件: TNFRSF17 💬 Belantamab mafodotin 💬 Belantamab mafodotin 1件: 28 💬
26 Intestinal immune network for IgA production 💬
1件: TNFRSF17 💬 Ciltacabtagene autoleucel 💬 Ciltacabtagene autoleucel 1件: 28 💬
27 Intestinal immune network for IgA production 💬
1件: TNFRSF17 💬 Idecabtagene vicleucel 💬 Idecabtagene vicleucel 1件: 28 💬
28 Intestinal immune network for IgA production 💬
1件: TNFRSF17 💬 Linvoseltamab 💬 Linvoseltamab 1件: 28 💬
29 Intestinal immune network for IgA production 💬
1件: TNFRSF17 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
30 Intestinal immune network for IgA production 💬
1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
31 Intestinal immune network for IgA production 💬
1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
32 Intestinal immune network for IgA production 💬
1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
33 Intestinal immune network for IgA production 💬
1件: TNFSF13 💬 Sibeprenlimab 💬 Sibeprenlimab 1件: 66 💬
34 Intestinal immune network for IgA production 💬
1件: TNFSF13 💬 Zigakibart 💬 Zigakibart 1件: 66 💬
35 Intestinal immune network for IgA production 💬
2件: TNFSF13, TNFSF13B 💬 Atacicept 💬 Atacicept 5件: 13, 46, 49, 66, 222 💬
36 Intestinal immune network for IgA production 💬
1件: TNFSF13B 💬 Belimumab 💬 Belimumab 14件: 11, 13, 43, 44, 46, 48, 49, 51, 53, 63, 66, 95, 222, 296 💬
37 Intestinal immune network for IgA production 💬
1件: TNFSF13B 💬 Tabalumab 💬 Tabalumab 2件: 46, 49 💬
38 Intestinal immune network for IgA production 💬
1件: TNFSF13B 💬 Tibulizumab 💬 Tibulizumab 2件: 51, 53 💬
39 Intestinal immune network for IgA production 💬
1件: TNFSF5 💬 Frexalimab 💬 Frexalimab 2件: 13, 222 💬
40 Intestinal immune network for IgA production 💬
1件: TNFSF5 💬 Toralizumab 💬 Toralizumab 1件: 63 💬