Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 GABAergic synapse 💬
 1件: ABAT 💬 Vigabatrin 💬 Vigabatrin 2件: 145, 158 💬
2 GABAergic synapse 💬
 3件: ABAT, E4.1.1.15, E4.1.1.15 💬 Divalproex sodium 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
3 GABAergic synapse 💬
 3件: ABAT, E4.1.1.15, E4.1.1.15 💬 Valproic acid 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
4 GABAergic synapse 💬
 3件: ABAT, E4.1.1.15, E4.1.1.15 💬 Valproate sodium 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
5 GABAergic synapse 💬
 5件: CACNA1B, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
6 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine 3件: 51, 67, 298 💬
7 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine 3件: 51, 67, 298 💬
8 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 3件: 51, 67, 298 💬
9 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine 3件: 51, 67, 298 💬
10 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol 1件:  8  💬
11 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem 4件: 51, 58, 86, 88 💬
12 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem 4件: 51, 58, 86, 88 💬
13 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 4件: 51, 58, 86, 88 💬
14 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
15 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine 2件: 70, 86 💬
16 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
17 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 1件: 81 💬
18 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
19 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
20 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
21 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
22 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
23 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil 4件: 58, 96, 140, 167 💬
24 GABAergic synapse 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
25 GABAergic synapse 💬
 20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
26 GABAergic synapse 💬
 1件: CACNA1S 💬 Pinaverium bromide 💬 Pinaverium 1件: 298 💬
27 GABAergic synapse 💬
 2件: GABBR, GABBR 💬 Arbaclofen 💬 Arbaclofen 2件: 13, 206 💬
28 GABAergic synapse 💬
 2件: GABBR, GABBR 💬 Valiloxybate 💬 Valiloxibic acid 1件:  6  💬
29 GABAergic synapse 💬
 2件: GABBR, GABBR 💬 Arbaclofen placarbil 💬 Arbaclofen Placarbil 1件: 13 💬
30 GABAergic synapse 💬
 2件: GABBR, GABBR 💬 Baclofen 💬 Baclofen 8件:  2 , 10, 13, 18, 65, 70, 149, 206 💬
31 GABAergic synapse 💬
 18件: GABBR, GABBR, GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 gamma-Aminobutyric acid 💬 gamma-Aminobutyric acid 1件: 140 💬
32 GABAergic synapse 💬
 1件: GABRA 💬 Etomidate 💬 Etomidate 2件:  6 , 11 💬
33 GABAergic synapse 💬
 1件: GABRA 💬 Alogabat 💬 Alogabat 1件: 201 💬
34 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Midazolam maleate 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
35 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
36 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Alprazolam 💬 Alprazolam 2件:  8 , 75 💬
37 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Clonazepam 💬 Clonazepam 1件:  6  💬
38 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Lorazepam 💬 Lorazepam 2件: 36, 231 💬
39 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Propofol 💬 Propofol 10件:  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬
40 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Midazolam hydrochloride 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
41 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Remimazolam besylate 💬 Remimazolam 1件:  6  💬
42 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Brexanolone 💬 Brexanolone 2件:  6 , 205 💬
43 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
44 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Chlordiazepoxide hydrochloride 💬 Chlordiazepoxide 1件: 46 💬
45 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Diazepam 💬 Diazepam 3件: 46, 155, 298 💬
46 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Remimazolam 💬 Remimazolam 1件:  6  💬
47 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Midazolam 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
48 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil 5件:  6 , 13, 17, 18, 206 💬
49 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Eszopiclone 💬 Eszopiclone 3件:  6 , 13, 46 💬
50 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem 3件:  5 ,  6 , 46 💬
51 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Chlordiazepoxide 💬 Chlordiazepoxide 1件: 46 💬
52 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Clobazam 💬 Clobazam 2件: 140, 144 💬
53 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Zolpidem tartrate 💬 Zolpidem 3件:  5 ,  6 , 46 💬
54 GABAergic synapse 💬
 16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Fospropofol disodium 💬 Fospropofol 1件: 226 💬
55 GABAergic synapse 💬
 1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
56 GABAergic synapse 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
57 GABAergic synapse 💬
 1件: SLC6A1 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
58 GABAergic synapse 💬
 1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
59 GABAergic synapse 💬
 1件: SRC 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
60 GABAergic synapse 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
61 GABAergic synapse 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
62 GABAergic synapse 💬
 1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬