Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Parathyroid hormone synthesis, secretion and action 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 Parathyroid hormone synthesis, secretion and action 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 Parathyroid hormone synthesis, secretion and action 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
4 Parathyroid hormone synthesis, secretion and action 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
5 Parathyroid hormone synthesis, secretion and action 💬
2件: BRAF, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
6 Parathyroid hormone synthesis, secretion and action 💬
2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
7 Parathyroid hormone synthesis, secretion and action 💬
1件: CASR 💬 Cinacalcet 💬 Cinacalcet 1件: 238 💬
8 Parathyroid hormone synthesis, secretion and action 💬
1件: CASR 💬 Cinacalcet hydrochloride 💬 Cinacalcet 1件: 238 💬
9 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
10 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
11 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
12 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
13 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
14 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
15 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
16 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
17 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
18 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
19 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
20 Parathyroid hormone synthesis, secretion and action 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
21 Parathyroid hormone synthesis, secretion and action 💬
1件: FGF23 💬 Burosumab 💬 Burosumab 1件: 238 💬
22 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
23 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 Infigratinib 💬 Infigratinib 1件: 276 💬
24 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 Infigratinib phosphate 💬 Infigratinib 1件: 276 💬
25 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
26 Parathyroid hormone synthesis, secretion and action 💬
1件: FGFR1 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
27 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
28 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
29 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
30 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
31 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
32 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
33 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
34 Parathyroid hormone synthesis, secretion and action 💬
1件: MAP2K1 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
35 Parathyroid hormone synthesis, secretion and action 💬
1件: MMP13 💬 Apratastat 💬 Apratastat 1件: 46 💬
36 Parathyroid hormone synthesis, secretion and action 💬
1件: PDE4 💬 Dipyridamole 💬 Dipyridamole 5件: 46, 51, 66, 96, 224 💬
37 Parathyroid hormone synthesis, secretion and action 💬
1件: PDE4 💬 Zatolmilast 💬 Zatolmilast 1件: 206 💬
38 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
39 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
40 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬
41 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Roflumilast 💬 Roflumilast 4件: 84, 97, 206, 299 💬
42 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
43 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
44 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
45 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Caffeine citrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
46 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
47 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
48 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
49 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
50 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
51 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Rolipram 💬 Rolipram 2件:  8 , 13 💬
52 Parathyroid hormone synthesis, secretion and action 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
53 Parathyroid hormone synthesis, secretion and action 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
54 Parathyroid hormone synthesis, secretion and action 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
55 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 Eneboparatide 💬 Eneboparatide 1件: 235 💬
56 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 Palopegteriparatide 💬 Palopegteriparatide 1件: 235 💬
57 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 Parathyroid hormone 💬 Parathyroid hormone 4件: 65, 70, 235, 326 💬
58 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 8件: 46, 65, 68, 70, 71, 172, 235, 274 💬
59 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 Teriparatide 💬 Teriparatide 8件: 46, 65, 68, 70, 71, 172, 235, 274 💬
60 Parathyroid hormone synthesis, secretion and action 💬
1件: PTH1R 💬 Teriparatide acetate 💬 Teriparatide 8件: 46, 65, 68, 70, 71, 172, 235, 274 💬
61 Parathyroid hormone synthesis, secretion and action 💬
3件: RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬
62 Parathyroid hormone synthesis, secretion and action 💬
3件: RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
63 Parathyroid hormone synthesis, secretion and action 💬
3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬
64 Parathyroid hormone synthesis, secretion and action 💬
1件: RXRB 💬 Tazarotene 💬 Tazarotene 1件: 85 💬
65 Parathyroid hormone synthesis, secretion and action 💬
1件: SLC12A3 💬 Bendroflumethiazide 💬 Bendroflumethiazide 1件: 67 💬
66 Parathyroid hormone synthesis, secretion and action 💬
1件: SLC12A3 💬 Chlorothiazide 💬 Chlorothiazide 1件: 225 💬
67 Parathyroid hormone synthesis, secretion and action 💬
1件: SLC12A3 💬 Chlorothiazide sodium 💬 Chlorothiazide 1件: 225 💬
68 Parathyroid hormone synthesis, secretion and action 💬
1件: SLC12A3 💬 Hydrochlorothiazide 💬 Hydrochlorothiazide 4件: 13, 67, 225, 235 💬
69 Parathyroid hormone synthesis, secretion and action 💬
1件: SLC12A3 💬 Indapamide 💬 Indapamide 1件: 13 💬
70 Parathyroid hormone synthesis, secretion and action 💬
1件: SOST 💬 Romosozumab 💬 Romosozumab 2件: 46, 274 💬
71 Parathyroid hormone synthesis, secretion and action 💬
1件: SOST 💬 Setrusumab 💬 Setrusumab 1件: 274 💬
72 Parathyroid hormone synthesis, secretion and action 💬
1件: TNFSF11 💬 Denosumab 💬 Denosumab 10件: 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
73 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Alfacalcidol 💬 Alfacalcidol 7件: 41, 46, 50, 96, 107, 235, 238 💬
74 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Calcifediol 💬 Calcifediol 2件: 86, 113 💬
75 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Calcipotriene 💬 Calcipotriol 2件: 36, 51 💬
76 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Calcipotriol hydrate 💬 Calcipotriol 2件: 36, 51 💬
77 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Calcitriol 💬 Calcitriol 8件: 18, 37, 46, 49, 66, 96, 235, 326 💬
78 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Cholecalciferol 💬 Cholecalciferol 23件:  6 , 11, 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 65, 84, 85, 96, 97, 98, 162, 228, 271, 298, 299 💬
79 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Eldecalcitol 💬 Eldecalcitol 1件: 46 💬
80 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Ergocalciferol 💬 Ergocalciferol 6件: 46, 49, 84, 96, 97, 299 💬
81 Parathyroid hormone synthesis, secretion and action 💬
1件: VDR 💬 Paricalcitol 💬 Paricalcitol 5件: 19, 66, 218, 238, 298 💬