Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Type II diabetes mellitus 💬
 2件: ABCC8, KCNJ11 💬 Diazoxide 💬 Diazoxide 2件: 13, 193 💬
2 Type II diabetes mellitus 💬
 2件: ABCC8, KCNJ11 💬 Diazoxide choline 💬 Diazoxide 2件: 13, 193 💬
3 Type II diabetes mellitus 💬
 2件: ABCC8, KCNJ11 💬 Minoxidil 💬 Minoxidil 1件: 179 💬
4 Type II diabetes mellitus 💬
 2件: ABCC8, KCNJ11 💬 Repaglinide 💬 Repaglinide 4件:  6 , 21, 46, 299 💬
5 Type II diabetes mellitus 💬
 3件: CACNA1B, CACNA1C, CACNA1D 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
6 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Amlodipine besylate 💬 Amlodipine 3件: 51, 67, 298 💬
7 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Amlodipine maleate 💬 Amlodipine 3件: 51, 67, 298 💬
8 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Amlodipine 💬 Amlodipine 3件: 51, 67, 298 💬
9 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Amlodipine benzoate 💬 Amlodipine 3件: 51, 67, 298 💬
10 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Bevantolol hydrochloride 💬 Bevantolol 1件:  8  💬
11 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem hydrochloride 💬 Diltiazem 4件: 51, 58, 86, 88 💬
12 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem malate 💬 Diltiazem 4件: 51, 58, 86, 88 💬
13 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Diltiazem 💬 Diltiazem 4件: 51, 58, 86, 88 💬
14 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Isradipine 💬 Isradipine 1件:  6  💬
15 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Nicardipine hydrochloride 💬 Nicardipine 2件: 70, 86 💬
16 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
17 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Nifedipine 💬 Nifedipine 1件: 81 💬
18 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
19 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
20 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
21 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
22 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Propiverine 💬 Propiverine 1件: 226 💬
23 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
24 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Verapamil hydrochloride 💬 Verapamil 4件: 58, 96, 140, 167 💬
25 Type II diabetes mellitus 💬
 2件: CACNA1C, CACNA1D 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
26 Type II diabetes mellitus 💬
 1件: CACNA1G 💬 Suvecaltamide 💬 Suvecaltamide 1件:  6  💬
27 Type II diabetes mellitus 💬
 1件: CACNA1G 💬 Divalproex sodium 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
28 Type II diabetes mellitus 💬
 1件: CACNA1G 💬 Valproic acid 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
29 Type II diabetes mellitus 💬
 1件: CACNA1G 💬 Valproate sodium 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
30 Type II diabetes mellitus 💬
 1件: CACNA1G 💬 Zonisamide 💬 Zonisamide 1件:  6  💬
31 Type II diabetes mellitus 💬
 1件: INSR 💬 Insulin detemir 💬 Insulin detemir 1件: 299 💬
32 Type II diabetes mellitus 💬
 1件: INSR 💬 Insulin glargine 💬 Insulin glargine 1件: 299 💬
33 Type II diabetes mellitus 💬
 1件: INSR 💬 Insulin human 💬 Insulin human 1件: 156 💬
34 Type II diabetes mellitus 💬
 1件: INSR 💬 Insulin lispro 💬 Insulin lispro 1件: 53 💬
35 Type II diabetes mellitus 💬
 1件: KCNJ11 💬 Amiodarone hydrochloride 💬 Amiodarone 1件: 127 💬
36 Type II diabetes mellitus 💬
 1件: KCNJ11 💬 Amiodarone 💬 Amiodarone 1件: 127 💬
37 Type II diabetes mellitus 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
38 Type II diabetes mellitus 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
39 Type II diabetes mellitus 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
40 Type II diabetes mellitus 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
41 Type II diabetes mellitus 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
42 Type II diabetes mellitus 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
43 Type II diabetes mellitus 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
44 Type II diabetes mellitus 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
45 Type II diabetes mellitus 💬
 2件: PRKCD, PRKCE 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
46 Type II diabetes mellitus 💬
 2件: PRKCD, PRKCE 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
47 Type II diabetes mellitus 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
48 Type II diabetes mellitus 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
49 Type II diabetes mellitus 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
50 Type II diabetes mellitus 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
51 Type II diabetes mellitus 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
52 Type II diabetes mellitus 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
53 Type II diabetes mellitus 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
54 Type II diabetes mellitus 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
55 Type II diabetes mellitus 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
56 Type II diabetes mellitus 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
57 Type II diabetes mellitus 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬