Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Insulin resistance 💬
2件: CPT1A, CPT1B 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
2 Insulin resistance 💬
2件: CPT1A, CPT1B 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
3 Insulin resistance 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
4 Insulin resistance 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
5 Insulin resistance 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
6 Insulin resistance 💬
2件: IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
7 Insulin resistance 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
8 Insulin resistance 💬
1件: INSR 💬 Insulin detemir 💬 Insulin detemir 1件: 299 💬
9 Insulin resistance 💬
1件: INSR 💬 Insulin glargine 💬 Insulin glargine 1件: 299 💬
10 Insulin resistance 💬
1件: INSR 💬 Insulin human 💬 Insulin human 1件: 156 💬
11 Insulin resistance 💬
1件: INSR 💬 Insulin lispro 💬 Insulin lispro 1件: 53 💬
12 Insulin resistance 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
13 Insulin resistance 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
14 Insulin resistance 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
15 Insulin resistance 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
16 Insulin resistance 💬
1件: NOS3 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
17 Insulin resistance 💬
1件: NR1C1 💬 Bezafibrate 💬 Bezafibrate 8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
18 Insulin resistance 💬
1件: NR1C1 💬 Elafibranor 💬 Elafibranor 2件: 93, 94 💬
19 Insulin resistance 💬
1件: NR1C1 💬 Fenofibrate 💬 Fenofibrate 6件:  8 , 79, 93, 94, 97, 265 💬
20 Insulin resistance 💬
1件: NR1C1 💬 Gemfibrozil 💬 Gemfibrozil 2件:  6 , 13 💬
21 Insulin resistance 💬
1件: NR1C1 💬 Pemafibrate 💬 Pemafibrate 1件: 93 💬
22 Insulin resistance 💬
1件: NR1C1 💬 Saroglitazar 💬 Saroglitazar 1件: 93 💬
23 Insulin resistance 💬
1件: NR1C1 💬 Saroglitazar magnesium 💬 Saroglitazar 1件: 93 💬
24 Insulin resistance 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
25 Insulin resistance 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
26 Insulin resistance 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
27 Insulin resistance 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
28 Insulin resistance 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
29 Insulin resistance 💬
2件: PRKAA, PRKAA 💬 Metformin 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
30 Insulin resistance 💬
2件: PRKAA, PRKAA 💬 Metformin hydrochloride 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
31 Insulin resistance 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
32 Insulin resistance 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
33 Insulin resistance 💬
3件: PRKCD, PRKCE, PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
34 Insulin resistance 💬
3件: PRKCD, PRKCE, PRKCQ 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
35 Insulin resistance 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
36 Insulin resistance 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
37 Insulin resistance 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
38 Insulin resistance 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
39 Insulin resistance 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
40 Insulin resistance 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
41 Insulin resistance 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
42 Insulin resistance 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
43 Insulin resistance 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
44 Insulin resistance 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬