Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Cushing syndrome 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
2 Cushing syndrome 💬
 1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
3 Cushing syndrome 💬
 1件: AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
4 Cushing syndrome 💬
 1件: AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil 1件: 66 💬
5 Cushing syndrome 💬
 1件: AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil 1件: 66 💬
6 Cushing syndrome 💬
 1件: AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil 1件: 66 💬
7 Cushing syndrome 💬
 1件: AGTR1 💬 Buloxibutid 💬 Buloxibutid 1件: 85 💬
8 Cushing syndrome 💬
 1件: AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid 1件: 85 💬
9 Cushing syndrome 💬
 1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
10 Cushing syndrome 💬
 1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
11 Cushing syndrome 💬
 1件: AGTR1 💬 Losartan potassium 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
12 Cushing syndrome 💬
 1件: AGTR1 💬 Losartan 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
13 Cushing syndrome 💬
 1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
14 Cushing syndrome 💬
 1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
15 Cushing syndrome 💬
 1件: AGTR1 💬 Valsartan 💬 Valsartan 8件: 57, 58, 66, 75, 86, 210, 222, 224 💬
16 Cushing syndrome 💬
 1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
17 Cushing syndrome 💬
 1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
18 Cushing syndrome 💬
 1件: BRAF 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
19 Cushing syndrome 💬
 1件: BRAF 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
20 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine 3件: 51, 67, 298 💬
21 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine 3件: 51, 67, 298 💬
22 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 3件: 51, 67, 298 💬
23 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine 3件: 51, 67, 298 💬
24 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol 1件:  8  💬
25 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
26 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem 4件: 51, 58, 86, 88 💬
27 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem 4件: 51, 58, 86, 88 💬
28 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 4件: 51, 58, 86, 88 💬
29 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
30 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine 2件: 70, 86 💬
31 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
32 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 1件: 81 💬
33 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
34 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
35 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
36 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
37 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
38 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
39 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil 4件: 58, 96, 140, 167 💬
40 Cushing syndrome 💬
 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
41 Cushing syndrome 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Suvecaltamide 💬 Suvecaltamide 1件:  6  💬
42 Cushing syndrome 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Divalproex sodium 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
43 Cushing syndrome 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Valproic acid 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
44 Cushing syndrome 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Valproate sodium 💬 Valproic acid 13件:  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 89, 90, 127, 222, 331 💬
45 Cushing syndrome 💬
 3件: CACNA1G, CACNA1H, CACNA1I 💬 Zonisamide 💬 Zonisamide 1件:  6  💬
46 Cushing syndrome 💬
 1件: CACNA1S 💬 Pinaverium bromide 💬 Pinaverium 1件: 298 💬
47 Cushing syndrome 💬
 2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
48 Cushing syndrome 💬
 1件: CRHR1 💬 Crinecerfont 💬 Crinecerfont 1件: 81 💬
49 Cushing syndrome 💬
 1件: CRHR1 💬 Tildacerfont 💬 Tildacerfont 1件: 81 💬
50 Cushing syndrome 💬
 2件: CRHR1, CRHR2 💬 Corticorelin 💬 Corticorelin 2件: 75, 205 💬
51 Cushing syndrome 💬
 3件: CYP11A, CYP11B1, CYP17A 💬 Levoketoconazole 💬 Levoketoconazole 1件: 75 💬
52 Cushing syndrome 💬
 1件: CYP11B1 💬 Metyrapone 💬 Metyrapone 1件: 75 💬
53 Cushing syndrome 💬
 1件: CYP17A 💬 Abiraterone acetate 💬 Abiraterone 2件: 75, 81 💬
54 Cushing syndrome 💬
 1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
55 Cushing syndrome 💬
 1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
56 Cushing syndrome 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
57 Cushing syndrome 💬
 1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
58 Cushing syndrome 💬
 1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
59 Cushing syndrome 💬
 1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
60 Cushing syndrome 💬
 1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
61 Cushing syndrome 💬
 1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
62 Cushing syndrome 💬
 1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
63 Cushing syndrome 💬
 1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
64 Cushing syndrome 💬
 1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
65 Cushing syndrome 💬
 1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
66 Cushing syndrome 💬
 1件: KCNA4 💬 Amifampridine 💬 Amifampridine 3件:  3 , 11, 12 💬
67 Cushing syndrome 💬
 1件: KCNA4 💬 Amifampridine phosphate 💬 Amifampridine 3件:  3 , 11, 12 💬
68 Cushing syndrome 💬
 1件: KCNA4 💬 Dalfampridine 💬 Dalfampridine 4件:  3 ,  4 , 13, 14 💬
69 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
70 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
71 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
72 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
73 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
74 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
75 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
76 Cushing syndrome 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
77 Cushing syndrome 💬
 1件: MC2R 💬 Corticotropin 💬 Corticotropin 11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
78 Cushing syndrome 💬
 1件: MC2R 💬 Corticotropin, repository 💬 Corticotropin 11件: 13, 46, 50, 66, 75, 78, 81, 84, 145, 205, 222 💬
79 Cushing syndrome 💬
 1件: MC2R 💬 Cosyntropin 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
80 Cushing syndrome 💬
 1件: MC2R 💬 Tetracosactide acetate 💬 Tetracosactide 5件: 78, 83, 113, 145, 222 💬
81 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
82 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
83 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
84 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
85 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
86 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
87 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
88 Cushing syndrome 💬
 3件: PDE11, PDE8, PDE8 💬 Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬