Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine 3件: 51, 67, 298 💬
2 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine 3件: 51, 67, 298 💬
3 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 3件: 51, 67, 298 💬
4 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine 3件: 51, 67, 298 💬
5 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol 1件:  8  💬
6 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
7 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem 4件: 51, 58, 86, 88 💬
8 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem 4件: 51, 58, 86, 88 💬
9 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 4件: 51, 58, 86, 88 💬
10 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
11 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine 2件: 70, 86 💬
12 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
13 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 1件: 81 💬
14 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
15 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
16 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
17 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
18 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
19 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
20 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil 4件: 58, 96, 140, 167 💬
21 Growth hormone synthesis, secretion and action 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
22 Growth hormone synthesis, secretion and action 💬
1件: CACNA1S 💬 Pinaverium bromide 💬 Pinaverium 1件: 298 💬
23 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
24 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
25 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 Pegvisomant 💬 Pegvisomant 2件: 77, 265 💬
26 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 Somapacitan 💬 Somapacitan 1件: 195 💬
27 Growth hormone synthesis, secretion and action 💬
1件: GHR 💬 Somatropin 💬 Somatotropin 28件:  2 ,  3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
28 Growth hormone synthesis, secretion and action 💬
1件: GHRHR 💬 Somatorelin 💬 Somatorelin 1件: 13 💬
29 Growth hormone synthesis, secretion and action 💬
1件: GHRHR 💬 Tesamorelin 💬 Tesamorelin 1件: 265 💬
30 Growth hormone synthesis, secretion and action 💬
1件: GHRHR 💬 Tesamorelin acetate 💬 Tesamorelin 1件: 265 💬
31 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
32 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
33 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
34 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
35 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
36 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
37 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
38 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
39 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
40 Growth hormone synthesis, secretion and action 💬
1件: JAK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
41 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
42 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
43 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
44 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
45 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
46 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
47 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
48 Growth hormone synthesis, secretion and action 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
49 Growth hormone synthesis, secretion and action 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
50 Growth hormone synthesis, secretion and action 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
51 Growth hormone synthesis, secretion and action 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
52 Growth hormone synthesis, secretion and action 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
53 Growth hormone synthesis, secretion and action 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
54 Growth hormone synthesis, secretion and action 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
55 Growth hormone synthesis, secretion and action 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
56 Growth hormone synthesis, secretion and action 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
57 Growth hormone synthesis, secretion and action 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
58 Growth hormone synthesis, secretion and action 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
59 Growth hormone synthesis, secretion and action 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
60 Growth hormone synthesis, secretion and action 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
61 Growth hormone synthesis, secretion and action 💬
1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
62 Growth hormone synthesis, secretion and action 💬
1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
63 Growth hormone synthesis, secretion and action 💬
4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 Pasireotide 💬 Pasireotide 4件: 67, 74, 75, 77 💬
64 Growth hormone synthesis, secretion and action 💬
4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 Pasireotide diaspartate 💬 Pasireotide 4件: 67, 74, 75, 77 💬
65 Growth hormone synthesis, secretion and action 💬
4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 Pasireotide pamoate 💬 Pasireotide 4件: 67, 74, 75, 77 💬
66 Growth hormone synthesis, secretion and action 💬
4件: SSTR1, SSTR2, SSTR3, SSTR5 💬 Somatostatin 💬 Somatostatin 1件: 77 💬
67 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 Edotreotide gallium Ga-68 💬 Dotatate gallium Ga-68 4件: 19, 75, 84, 238 💬
68 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 Octreotide 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
69 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 Octreotide acetate 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
70 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 Octreotide pamoate 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
71 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 Octreotide acetate 💬 Octreotide 8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
72 Growth hormone synthesis, secretion and action 💬
1件: SSTR2 💬 Paltusotine 💬 Paltusotine 1件: 77 💬
73 Growth hormone synthesis, secretion and action 💬
2件: SSTR2, SSTR5 💬 Lanreotide acetate 💬 Lanreotide 5件: 67, 73, 77, 85, 298 💬