Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Huntington disease 💬
1件: CACNA1B 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
2 Huntington disease 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
3 Huntington disease 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel 💬 Perampanel 3件:  2 ,  6 , 144 💬
4 Huntington disease 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel hydrate 💬 Perampanel 3件:  2 ,  6 , 144 💬
5 Huntington disease 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Talampanel 💬 Talampanel 2件:  2 ,  6  💬
6 Huntington disease 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
7 Huntington disease 💬
6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2B 💬 Riluzole 💬 Riluzole 8件:  2 ,  3 ,  5 ,  8 , 13, 17, 203, 206 💬
8 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Acamprosate calcium 💬 Acamprosate 2件:  6 , 206 💬
9 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Acamprosate 💬 Acamprosate 2件:  6 , 206 💬
10 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Amantadine hydrochloride 💬 Amantadine 5件:  2 ,  6 ,  8 , 13, 127 💬
11 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Amantadine 💬 Amantadine 5件:  2 ,  6 ,  8 , 13, 127 💬
12 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Dextromethorphan hydrobromide 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
13 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
14 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Esketamine 💬 Esketamine 7件:  2 ,  4 ,  6 , 70, 96, 97, 156 💬
15 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Esketamine hydrochloride 💬 Esketamine 7件:  2 ,  4 ,  6 , 70, 96, 97, 156 💬
16 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Ketamine hydrochloride 💬 Ketamine 6件:  6 , 13, 70, 113, 156, 215 💬
17 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Ketamine 💬 Ketamine 6件:  6 , 13, 70, 113, 156, 215 💬
18 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬
19 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Latrepirdine dihydrochloride 💬 Latrepirdine 1件:  8  💬
20 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Memantine hydrochloride 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
21 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
22 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Methadone hydrochloride 💬 Methadone 1件: 60 💬
23 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Methadone 💬 Methadone 1件: 60 💬
24 Huntington disease 💬
2件: GRIN1, GRIN2B 💬 Tenocyclidine 💬 Tenocyclidine 1件: 36 💬
25 Huntington disease 💬
1件: HD 💬 Tominersen 💬 Tominersen 1件:  8  💬
26 Huntington disease 💬
2件: HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat 2件: 107, 113 💬
27 Huntington disease 💬
2件: HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
28 Huntington disease 💬
3件: HDAC1_2, HDAC1_2, PIK3C3 💬 Fimepinostat 💬 Fimepinostat 1件: 75 💬
29 Huntington disease 💬
1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬
30 Huntington disease 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
31 Huntington disease 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
32 Huntington disease 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
33 Huntington disease 💬
1件: NR1C3 💬 Bocidelpar 💬 Bocidelpar 1件: 113 💬
34 Huntington disease 💬
1件: NR1C3 💬 Bocidelpar sulfate 💬 Bocidelpar 1件: 113 💬
35 Huntington disease 💬
1件: NR1C3 💬 Leriglitazone 💬 Leriglitazone 1件: 20 💬
36 Huntington disease 💬
1件: NR1C3 💬 Pioglitazone hydrochloride 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 220, 229, 265, 298, 299 💬
37 Huntington disease 💬
1件: NR1C3 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 220, 229, 265, 298, 299 💬
38 Huntington disease 💬
1件: NR1C3 💬 Rosiglitazone maleate 💬 Rosiglitazone 6件: 46, 75, 77, 97, 222, 265 💬
39 Huntington disease 💬
1件: NR1C3 💬 Rosiglitazone 💬 Rosiglitazone 6件: 46, 75, 77, 97, 222, 265 💬
40 Huntington disease 💬
1件: NR1C3 💬 Saroglitazar 💬 Saroglitazar 1件: 93 💬
41 Huntington disease 💬
1件: NR1C3 💬 Saroglitazar magnesium 💬 Saroglitazar 1件: 93 💬
42 Huntington disease 💬
1件: NR1C3 💬 Seladelpar 💬 Seladelpar 2件: 93, 94 💬
43 Huntington disease 💬
1件: NR1C3 💬 Seladelpar lysine 💬 Seladelpar 2件: 93, 94 💬
44 Huntington disease 💬
1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
45 Huntington disease 💬
1件: PSMB5 💬 Carfilzomib 💬 Carfilzomib 1件: 28 💬
46 Huntington disease 💬
1件: PSMB5 💬 Ixazomib 💬 Ixazomib 4件: 13, 16, 28, 51 💬
47 Huntington disease 💬
1件: PSMB5 💬 Ixazomib citrate 💬 Ixazomib 4件: 13, 16, 28, 51 💬
48 Huntington disease 💬
1件: SOD1 💬 Tofersen 💬 Tofersen 1件:  2  💬
49 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Belantamab mafodotin 💬 Belantamab mafodotin 1件: 28 💬
50 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Brentuximab vedotin 💬 Brentuximab vedotin 2件: 49, 51 💬
51 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine 💬 Vinblastine 3件: 34, 63, 65 💬
52 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Paclitaxel 💬 Paclitaxel 1件: 85 💬
53 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine sulfate 💬 Vincristine 3件: 26, 34, 331 💬
54 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Colchicine 💬 Colchicine 9件:  2 , 42, 46, 50, 56, 93, 97, 210, 266 💬
55 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vincristine 💬 Vincristine 3件: 26, 34, 331 💬
56 Huntington disease 💬
9件: TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB, TUBB 💬 Vinblastine sulfate 💬 Vinblastine 3件: 34, 63, 65 💬