Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Nicotine addiction 💬
1件: CACNA1B 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
2 Nicotine addiction 💬
4件: CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 Nicotine 💬 Nicotine 3件:  6 , 13, 84 💬
3 Nicotine addiction 💬
4件: CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 Nicotine bitartrate 💬 Nicotine 3件:  6 , 13, 84 💬
4 Nicotine addiction 💬
4件: CHRNA4, CHRNA6, CHRNA7, CHRNB2 💬 Rocuronium bromide 💬 Rocuronium 2件: 70, 296 💬
5 Nicotine addiction 💬
2件: CHRNA4, CHRNB2 💬 Varenicline tartrate 💬 Varenicline 3件:  6 , 18, 53 💬
6 Nicotine addiction 💬
2件: CHRNA4, CHRNB2 💬 Varenicline 💬 Varenicline 3件:  6 , 18, 53 💬
7 Nicotine addiction 💬
1件: GABRA 💬 Etomidate 💬 Etomidate 2件:  6 , 11 💬
8 Nicotine addiction 💬
1件: GABRA 💬 Alogabat 💬 Alogabat 1件: 201 💬
9 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Alprazolam 💬 Alprazolam 2件:  8 , 75 💬
10 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Remimazolam besylate 💬 Remimazolam 1件:  6  💬
11 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Brexanolone 💬 Brexanolone 2件:  6 , 205 💬
12 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Fospropofol disodium 💬 Fospropofol 1件: 226 💬
13 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Chlordiazepoxide hydrochloride 💬 Chlordiazepoxide 1件: 46 💬
14 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Chlordiazepoxide 💬 Chlordiazepoxide 1件: 46 💬
15 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Clonazepam 💬 Clonazepam 1件:  6  💬
16 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Remimazolam 💬 Remimazolam 1件:  6  💬
17 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Gaboxadol 💬 Gaboxadol 2件: 201, 206 💬
18 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Zolpidem 💬 Zolpidem 3件:  5 ,  6 , 46 💬
19 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 gamma-Aminobutyric acid 💬 gamma-Aminobutyric acid 1件: 140 💬
20 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Ganaxolone 💬 Ganaxolone 4件: 145, 152, 158, 206 💬
21 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Midazolam maleate 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
22 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Midazolam hydrochloride 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
23 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Propofol 💬 Propofol 10件:  3 ,  6 , 21, 22, 34, 46, 70, 97, 98, 296 💬
24 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Diazepam 💬 Diazepam 3件: 46, 155, 298 💬
25 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Flumazenil 💬 Flumazenil 5件:  6 , 13, 17, 18, 206 💬
26 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Midazolam 💬 Midazolam 13件:  2 ,  3 ,  6 , 13, 21, 46, 67, 96, 97, 231, 272, 298, 299 💬
27 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Zolpidem tartrate 💬 Zolpidem 3件:  5 ,  6 , 46 💬
28 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Clobazam 💬 Clobazam 2件: 140, 144 💬
29 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Eszopiclone 💬 Eszopiclone 3件:  6 , 13, 46 💬
30 Nicotine addiction 💬
16件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ 💬 Lorazepam 💬 Lorazepam 2件: 36, 231 💬
31 Nicotine addiction 💬
20件: GABRA, GABRA, GABRA, GABRA, GABRA, GABRA, GABRB, GABRB, GABRB, GABRD, GABRE, GABRG, GABRG, GABRG, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
32 Nicotine addiction 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel 💬 Perampanel 3件:  2 ,  6 , 144 💬
33 Nicotine addiction 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Perampanel hydrate 💬 Perampanel 3件:  2 ,  6 , 144 💬
34 Nicotine addiction 💬
4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 Talampanel 💬 Talampanel 2件:  2 ,  6  💬
35 Nicotine addiction 💬
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Riluzole 💬 Riluzole 8件:  2 ,  3 ,  5 ,  8 , 13, 17, 203, 206 💬
36 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate calcium 💬 Acamprosate 2件:  6 , 206 💬
37 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Acamprosate 💬 Acamprosate 2件:  6 , 206 💬
38 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine hydrochloride 💬 Amantadine 5件:  2 ,  6 ,  8 , 13, 127 💬
39 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Amantadine 💬 Amantadine 5件:  2 ,  6 ,  8 , 13, 127 💬
40 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan hydrobromide 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
41 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Dextromethorphan 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
42 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine 💬 Esketamine 7件:  2 ,  4 ,  6 , 70, 96, 97, 156 💬
43 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Esketamine hydrochloride 💬 Esketamine 7件:  2 ,  4 ,  6 , 70, 96, 97, 156 💬
44 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine hydrochloride 💬 Ketamine 6件:  6 , 13, 70, 113, 156, 215 💬
45 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Ketamine 💬 Ketamine 6件:  6 , 13, 70, 113, 156, 215 💬
46 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬
47 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Latrepirdine dihydrochloride 💬 Latrepirdine 1件:  8  💬
48 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine hydrochloride 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
49 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
50 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Methadone hydrochloride 💬 Methadone 1件: 60 💬
51 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Methadone 💬 Methadone 1件: 60 💬
52 Nicotine addiction 💬
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 Tenocyclidine 💬 Tenocyclidine 1件: 36 💬