Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Toxoplasmosis 💬
1件: ALOX5 💬 Oxatomide 💬 Oxatomide 1件: 113 💬
2 Toxoplasmosis 💬
1件: ALOX5 💬 Zileuton 💬 Zileuton 3件: 85, 160, 164 💬
3 Toxoplasmosis 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
4 Toxoplasmosis 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
5 Toxoplasmosis 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
6 Toxoplasmosis 💬
1件: CCR5 💬 Cenicriviroc 💬 Cenicriviroc 1件: 94 💬
7 Toxoplasmosis 💬
1件: CCR5 💬 Cenicriviroc mesylate 💬 Cenicriviroc 1件: 94 💬
8 Toxoplasmosis 💬
1件: CCR5 💬 Maraviroc 💬 Maraviroc 1件: 46 💬
9 Toxoplasmosis 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
10 Toxoplasmosis 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
11 Toxoplasmosis 💬
2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
12 Toxoplasmosis 💬
2件: IL10, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
13 Toxoplasmosis 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
14 Toxoplasmosis 💬
1件: ITGB1 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
15 Toxoplasmosis 💬
1件: ITGB1 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
16 Toxoplasmosis 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
17 Toxoplasmosis 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
18 Toxoplasmosis 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
19 Toxoplasmosis 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
20 Toxoplasmosis 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
21 Toxoplasmosis 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
22 Toxoplasmosis 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
23 Toxoplasmosis 💬
2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
24 Toxoplasmosis 💬
2件: JAK1, JAK2 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
25 Toxoplasmosis 💬
2件: JAK1, JAK2 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
26 Toxoplasmosis 💬
2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
27 Toxoplasmosis 💬
2件: JAK1, JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
28 Toxoplasmosis 💬
3件: JAK1, JAK2, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
29 Toxoplasmosis 💬
3件: JAK1, JAK2, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
30 Toxoplasmosis 💬
3件: JAK1, JAK2, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
31 Toxoplasmosis 💬
3件: JAK1, JAK2, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
32 Toxoplasmosis 💬
1件: JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
33 Toxoplasmosis 💬
14件: MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
34 Toxoplasmosis 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
35 Toxoplasmosis 💬
1件: NOS2 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
36 Toxoplasmosis 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
37 Toxoplasmosis 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
38 Toxoplasmosis 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
39 Toxoplasmosis 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
40 Toxoplasmosis 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
41 Toxoplasmosis 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
42 Toxoplasmosis 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
43 Toxoplasmosis 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
44 Toxoplasmosis 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
45 Toxoplasmosis 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
46 Toxoplasmosis 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
47 Toxoplasmosis 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
48 Toxoplasmosis 💬
1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
49 Toxoplasmosis 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
50 Toxoplasmosis 💬
1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
51 Toxoplasmosis 💬
1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
52 Toxoplasmosis 💬
1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
53 Toxoplasmosis 💬
1件: TNFSF5 💬 Frexalimab 💬 Frexalimab 2件: 13, 222 💬
54 Toxoplasmosis 💬
1件: TNFSF5 💬 Toralizumab 💬 Toralizumab 1件: 63 💬
55 Toxoplasmosis 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
56 Toxoplasmosis 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬