Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Hepatitis C 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
2 Hepatitis C 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
3 Hepatitis C 💬
2件: BRAF, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
4 Hepatitis C 💬
2件: BRAF, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
5 Hepatitis C 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
6 Hepatitis C 💬
2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
7 Hepatitis C 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
8 Hepatitis C 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
9 Hepatitis C 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
10 Hepatitis C 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
11 Hepatitis C 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
12 Hepatitis C 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
13 Hepatitis C 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
14 Hepatitis C 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
15 Hepatitis C 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
16 Hepatitis C 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
17 Hepatitis C 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
18 Hepatitis C 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
19 Hepatitis C 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
20 Hepatitis C 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
21 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
22 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
23 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
24 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
25 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
26 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
27 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
28 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
29 Hepatitis C 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
30 Hepatitis C 💬
1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
31 Hepatitis C 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
32 Hepatitis C 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
33 Hepatitis C 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
34 Hepatitis C 💬
1件: JAK1 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
35 Hepatitis C 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
36 Hepatitis C 💬
1件: JAK1 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
37 Hepatitis C 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
38 Hepatitis C 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
39 Hepatitis C 💬
1件: JAK1 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
40 Hepatitis C 💬
1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
41 Hepatitis C 💬
1件: JAK1 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
42 Hepatitis C 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
43 Hepatitis C 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
44 Hepatitis C 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
45 Hepatitis C 💬
2件: JAK1, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
46 Hepatitis C 💬
2件: JAK1, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
47 Hepatitis C 💬
2件: JAK1, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
48 Hepatitis C 💬
2件: JAK1, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
49 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
50 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
51 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
52 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
53 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
54 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
55 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
56 Hepatitis C 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
57 Hepatitis C 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
58 Hepatitis C 💬
1件: NR1C1 💬 Bezafibrate 💬 Bezafibrate 8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
59 Hepatitis C 💬
1件: NR1C1 💬 Elafibranor 💬 Elafibranor 2件: 93, 94 💬
60 Hepatitis C 💬
1件: NR1C1 💬 Fenofibrate 💬 Fenofibrate 6件:  8 , 79, 93, 94, 97, 265 💬
61 Hepatitis C 💬
1件: NR1C1 💬 Gemfibrozil 💬 Gemfibrozil 2件:  6 , 13 💬
62 Hepatitis C 💬
1件: NR1C1 💬 Pemafibrate 💬 Pemafibrate 1件: 93 💬
63 Hepatitis C 💬
1件: NR1C1 💬 Saroglitazar 💬 Saroglitazar 1件: 93 💬
64 Hepatitis C 💬
1件: NR1C1 💬 Saroglitazar magnesium 💬 Saroglitazar 1件: 93 💬
65 Hepatitis C 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
66 Hepatitis C 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
67 Hepatitis C 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
68 Hepatitis C 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
69 Hepatitis C 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
70 Hepatitis C 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
71 Hepatitis C 💬
1件: RIPK1 💬 Eclitasertib 💬 SAR443122 1件: 97 💬
72 Hepatitis C 💬
1件: RXRA 💬 Acitretin 💬 Acitretin 1件: 37 💬
73 Hepatitis C 💬
1件: RXRA 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
74 Hepatitis C 💬
1件: RXRA 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬
75 Hepatitis C 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
76 Hepatitis C 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
77 Hepatitis C 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
78 Hepatitis C 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
79 Hepatitis C 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
80 Hepatitis C 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
81 Hepatitis C 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
82 Hepatitis C 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
83 Hepatitis C 💬
1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
84 Hepatitis C 💬
1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
85 Hepatitis C 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
86 Hepatitis C 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
87 Hepatitis C 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬