Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human papillomavirus infection 💬
 1件: ATR 💬 Tuvusertib 💬 Tuvusertib 1件: 65 💬
2 Human papillomavirus infection 💬
 2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
3 Human papillomavirus infection 💬
 1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
4 Human papillomavirus infection 💬
 1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
5 Human papillomavirus infection 💬
 1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
6 Human papillomavirus infection 💬
 1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
7 Human papillomavirus infection 💬
 1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
8 Human papillomavirus infection 💬
 1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
9 Human papillomavirus infection 💬
 1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
10 Human papillomavirus infection 💬
 1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
11 Human papillomavirus infection 💬
 1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
12 Human papillomavirus infection 💬
 1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
13 Human papillomavirus infection 💬
 1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
14 Human papillomavirus infection 💬
 1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
15 Human papillomavirus infection 💬
 2件: HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat 2件: 107, 113 💬
16 Human papillomavirus infection 💬
 2件: HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
17 Human papillomavirus infection 💬
 2件: HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat 1件: 75 💬
18 Human papillomavirus infection 💬
 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
19 Human papillomavirus infection 💬
 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
20 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
21 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
22 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
23 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
24 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
25 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
26 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
27 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
28 Human papillomavirus infection 💬
 2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
29 Human papillomavirus infection 💬
 1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
30 Human papillomavirus infection 💬
 1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬
31 Human papillomavirus infection 💬
 1件: ITGA4 💬 Natalizumab 💬 Natalizumab 5件: 13, 15, 25, 46, 96 💬
32 Human papillomavirus infection 💬
 3件: ITGA4, ITGB1, ITGB7 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
33 Human papillomavirus infection 💬
 2件: ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬
34 Human papillomavirus infection 💬
 2件: ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬
35 Human papillomavirus infection 💬
 3件: ITGA5, ITGB1, ITGB6 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
36 Human papillomavirus infection 💬
 1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬
37 Human papillomavirus infection 💬
 1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
38 Human papillomavirus infection 💬
 1件: JAK1 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
39 Human papillomavirus infection 💬
 1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
40 Human papillomavirus infection 💬
 1件: JAK1 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
41 Human papillomavirus infection 💬
 1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
42 Human papillomavirus infection 💬
 1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
43 Human papillomavirus infection 💬
 1件: JAK1 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
44 Human papillomavirus infection 💬
 1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
45 Human papillomavirus infection 💬
 1件: JAK1 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
46 Human papillomavirus infection 💬
 1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
47 Human papillomavirus infection 💬
 1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
48 Human papillomavirus infection 💬
 1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
49 Human papillomavirus infection 💬
 2件: JAK1, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
50 Human papillomavirus infection 💬
 2件: JAK1, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
51 Human papillomavirus infection 💬
 2件: JAK1, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
52 Human papillomavirus infection 💬
 2件: JAK1, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
53 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
54 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
55 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
56 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
57 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
58 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
59 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
60 Human papillomavirus infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
61 Human papillomavirus infection 💬
 6件: MHC1, MHC1, MHC1, MHC1, MHC1, MHC1 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
62 Human papillomavirus infection 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
63 Human papillomavirus infection 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
64 Human papillomavirus infection 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
65 Human papillomavirus infection 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
66 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
67 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
68 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
69 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
70 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
71 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
72 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
73 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Seralutinib 💬 Seralutinib 1件: 86 💬
74 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
75 Human papillomavirus infection 💬
 1件: PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
76 Human papillomavirus infection 💬
 2件: PDGFRB, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
77 Human papillomavirus infection 💬
 2件: PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
78 Human papillomavirus infection 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
79 Human papillomavirus infection 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
80 Human papillomavirus infection 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
81 Human papillomavirus infection 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
82 Human papillomavirus infection 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
83 Human papillomavirus infection 💬
 1件: PSEN1 💬 Tarenflurbil 💬 Tarenflurbil 1件: 13 💬
84 Human papillomavirus infection 💬
 1件: PTGER4 💬 Misoprostol 💬 Misoprostol 3件: 46, 70, 271 💬
85 Human papillomavirus infection 💬
 1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
86 Human papillomavirus infection 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
87 Human papillomavirus infection 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
88 Human papillomavirus infection 💬
 1件: PTGS2 💬 Celecoxib 💬 Celecoxib 14件:  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
89 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diclofenac potassium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
90 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diclofenac sodium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
91 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 4件: 13, 34, 46, 271 💬
92 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diclofenac diethylamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
93 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diclofenac epolamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
94 Human papillomavirus infection 💬
 1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
95 Human papillomavirus infection 💬
 1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 3件: 46, 70, 271 💬
96 Human papillomavirus infection 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
97 Human papillomavirus infection 💬
 1件: PTGS2 💬 Flurbiprofen sodium 💬 Flurbiprofen 3件: 13, 21, 46 💬
98 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
99 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ibuprofen aluminum 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
100 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ibuprofen lysine 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
101 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
102 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
103 Human papillomavirus infection 💬
 1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
104 Human papillomavirus infection 💬
 1件: PTGS2 💬 Indomethacin sodium 💬 Indomethacin 3件: 225, 271, 298 💬
105 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 2件: 13, 46 💬
106 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ketoprofen lysine 💬 Ketoprofen 2件: 13, 46 💬
107 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ketoprofen sodium 💬 Ketoprofen 2件: 13, 46 💬
108 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ketorolac tromethamine 💬 Ketorolac 2件: 70, 226 💬
109 Human papillomavirus infection 💬
 1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
110 Human papillomavirus infection 💬
 1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
111 Human papillomavirus infection 💬
 1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
112 Human papillomavirus infection 💬
 1件: PTGS2 💬 Meloxicam 💬 Meloxicam 3件: 46, 271, 296 💬
113 Human papillomavirus infection 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
114 Human papillomavirus infection 💬
 1件: PTGS2 💬 Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
115 Human papillomavirus infection 💬
 1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
116 Human papillomavirus infection 💬
 1件: PTGS2 💬 Valdecoxib 💬 Parecoxib 2件: 46, 271 💬
117 Human papillomavirus infection 💬
 1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
118 Human papillomavirus infection 💬
 1件: PTGS2 💬 Parecoxib sodium 💬 Parecoxib 2件: 46, 271 💬
119 Human papillomavirus infection 💬
 1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
120 Human papillomavirus infection 💬
 1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
121 Human papillomavirus infection 💬
 1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
122 Human papillomavirus infection 💬
 1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
123 Human papillomavirus infection 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
124 Human papillomavirus infection 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
125 Human papillomavirus infection 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
126 Human papillomavirus infection 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
127 Human papillomavirus infection 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
128 Human papillomavirus infection 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
129 Human papillomavirus infection 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
130 Human papillomavirus infection 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
131 Human papillomavirus infection 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
132 Human papillomavirus infection 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
133 Human papillomavirus infection 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
134 Human papillomavirus infection 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
135 Human papillomavirus infection 💬
 1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
136 Human papillomavirus infection 💬
 1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬
137 Human papillomavirus infection 💬
 1件: VEGFA 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬
138 Human papillomavirus infection 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 8件: 13, 34, 85, 87, 89, 227, 280, 331 💬
139 Human papillomavirus infection 💬
 1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬
140 Human papillomavirus infection 💬
 1件: VWF 💬 Caplacizumab 💬 Caplacizumab 2件: 63, 64 💬