Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Human T-cell leukemia virus 1 infection 💬
 1件: ATR 💬 Tuvusertib 💬 Tuvusertib 1件: 65 💬
2 Human T-cell leukemia virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
3 Human T-cell leukemia virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Muromonab-CD3 💬 Muromonab 3件: 60, 96, 97 💬
4 Human T-cell leukemia virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
5 Human T-cell leukemia virus 1 infection 💬
 3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
6 Human T-cell leukemia virus 1 infection 💬
 6件: CD3D, CD3E, CD3G, CD4, IL2RA, ITGAL 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
7 Human T-cell leukemia virus 1 infection 💬
 1件: CD3E 💬 Elranatamab 💬 Elranatamab 1件: 28 💬
8 Human T-cell leukemia virus 1 infection 💬
 1件: CD3E 💬 Imvotamab 💬 Imvotamab 2件: 46, 49 💬
9 Human T-cell leukemia virus 1 infection 💬
 1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
10 Human T-cell leukemia virus 1 infection 💬
 1件: CD3E 💬 Talquetamab 💬 Talquetamab 1件: 28 💬
11 Human T-cell leukemia virus 1 infection 💬
 1件: CD3E 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
12 Human T-cell leukemia virus 1 infection 💬
 1件: CD4 💬 Zanolimumab 💬 Zanolimumab 1件: 46 💬
13 Human T-cell leukemia virus 1 infection 💬
 1件: CDK4 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
14 Human T-cell leukemia virus 1 infection 💬
 1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
15 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Alendronate sodium 💬 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299 💬
16 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Alendronic acid 💬 Alendronic acid 7件: 19, 41, 46, 50, 271, 274, 299 💬
17 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Ibandronate sodium 💬 Ibandronate 3件: 46, 49, 274 💬
18 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Ibandronic acid 💬 Ibandronate 3件: 46, 49, 274 💬
19 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Pamidronate disodium 💬 Pamidronic acid 3件: 270, 271, 274 💬
20 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Pamidronic acid 💬 Pamidronic acid 3件: 270, 271, 274 💬
21 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Risedronate sodium 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
22 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Risedronic acid 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
23 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Risedronate sodium monohydrate 💬 Risedronic acid 9件: 46, 50, 66, 93, 95, 96, 107, 113, 274 💬
24 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronic acid 💬 Zoledronic acid 16件:  5 ,  6 , 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
25 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronate disodium 💬 Zoledronic acid 16件:  5 ,  6 , 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
26 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronate trisodium 💬 Zoledronic acid 16件:  5 ,  6 , 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
27 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronic acid 💬 Zoledronic acid 16件:  5 ,  6 , 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
28 Human T-cell leukemia virus 1 infection 💬
 1件: FDPS 💬 Zoledronic acid hemipentahydrate 💬 Zoledronic acid 16件:  5 ,  6 , 13, 17, 46, 65, 75, 77, 93, 95, 96, 97, 270, 274, 299, 333 💬
29 Human T-cell leukemia virus 1 infection 💬
 1件: ICAM1 💬 Alicaforsen sodium 💬 Alicaforsen 2件: 96, 97 💬
30 Human T-cell leukemia virus 1 infection 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
31 Human T-cell leukemia virus 1 infection 💬
 1件: IL2RA 💬 Basiliximab 💬 Basiliximab 5件:  2 , 50, 97, 222, 228 💬
32 Human T-cell leukemia virus 1 infection 💬
 1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
33 Human T-cell leukemia virus 1 infection 💬
 3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
34 Human T-cell leukemia virus 1 infection 💬
 1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
35 Human T-cell leukemia virus 1 infection 💬
 1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
36 Human T-cell leukemia virus 1 infection 💬
 1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
37 Human T-cell leukemia virus 1 infection 💬
 2件: IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
38 Human T-cell leukemia virus 1 infection 💬
 2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
39 Human T-cell leukemia virus 1 infection 💬
 1件: ITGAL 💬 Efalizumab 💬 Efalizumab 9件: 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
40 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
41 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
42 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
43 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
44 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
45 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
46 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
47 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
48 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
49 Human T-cell leukemia virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
50 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
51 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
52 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
53 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
54 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
55 Human T-cell leukemia virus 1 infection 💬
 2件: JAK1, JAK3 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
56 Human T-cell leukemia virus 1 infection 💬
 1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
57 Human T-cell leukemia virus 1 infection 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
58 Human T-cell leukemia virus 1 infection 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
59 Human T-cell leukemia virus 1 infection 💬
 1件: LTA 💬 Pateclizumab 💬 Pateclizumab 1件: 46 💬
60 Human T-cell leukemia virus 1 infection 💬
 2件: LTA, TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
61 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
62 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
63 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
64 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
65 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
66 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
67 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
68 Human T-cell leukemia virus 1 infection 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
69 Human T-cell leukemia virus 1 infection 💬
 20件: MHC1, MHC1, MHC1, MHC1, MHC1, MHC1, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
70 Human T-cell leukemia virus 1 infection 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
71 Human T-cell leukemia virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
72 Human T-cell leukemia virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
73 Human T-cell leukemia virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
74 Human T-cell leukemia virus 1 infection 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
75 Human T-cell leukemia virus 1 infection 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
76 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
77 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
78 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Cyclosporine 💬 Cyclosporine 42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
79 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬
80 Human T-cell leukemia virus 1 infection 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬
81 Human T-cell leukemia virus 1 infection 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
82 Human T-cell leukemia virus 1 infection 💬
 3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
83 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
84 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
85 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
86 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
87 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
88 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
89 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
90 Human T-cell leukemia virus 1 infection 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
91 Human T-cell leukemia virus 1 infection 💬
 1件: TNFRSF13C 💬 Ianalumab 💬 Ianalumab 8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
92 Human T-cell leukemia virus 1 infection 💬
 1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
93 Human T-cell leukemia virus 1 infection 💬
 1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
94 Human T-cell leukemia virus 1 infection 💬
 1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
95 Human T-cell leukemia virus 1 infection 💬
 1件: XPO1 💬 Selinexor 💬 Selinexor 1件: 28 💬