Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Herpes simplex virus 1 infection 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 Herpes simplex virus 1 infection 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 Herpes simplex virus 1 infection 💬
 1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬
4 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Avacincaptad pegol sodium 💬 Avacincaptad pegol 1件: 301 💬
5 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Crovalimab 💬 Crovalimab 2件: 62, 109 💬
6 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
7 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Gefurulimab 💬 Gefurulimab 1件: 11 💬
8 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Nomacopan 💬 Nomacopan 3件: 62, 109, 162 💬
9 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Pozelimab 💬 Pozelimab 3件: 11, 15, 62 💬
10 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬
11 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬
12 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Zilucoplan sodium 💬 Zilucoplan 2件: 11, 62 💬
13 Herpes simplex virus 1 infection 💬
 1件: C5 💬 Zilucoplan 💬 Zilucoplan 2件: 11, 62 💬
14 Herpes simplex virus 1 infection 💬
 1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
15 Herpes simplex virus 1 infection 💬
 4件: CCL2, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
16 Herpes simplex virus 1 infection 💬
 1件: CD74 💬 Milatuzumab 💬 Milatuzumab 1件: 49 💬
17 Herpes simplex virus 1 infection 💬
 5件: EIF2B1, EIF2B2, EIF2B3, EIF2B4, EIF2B5 💬 Fosigotifator 💬 Fosigotifator 2件:  2 , 308 💬
18 Herpes simplex virus 1 infection 💬
 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
19 Herpes simplex virus 1 infection 💬
 13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
20 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
21 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
22 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
23 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
24 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
25 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
26 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
27 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
28 Herpes simplex virus 1 infection 💬
 2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
29 Herpes simplex virus 1 infection 💬
 1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
30 Herpes simplex virus 1 infection 💬
 1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
31 Herpes simplex virus 1 infection 💬
 1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
32 Herpes simplex virus 1 infection 💬
 2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
33 Herpes simplex virus 1 infection 💬
 2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
34 Herpes simplex virus 1 infection 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
35 Herpes simplex virus 1 infection 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
36 Herpes simplex virus 1 infection 💬
 1件: IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
37 Herpes simplex virus 1 infection 💬
 1件: IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
38 Herpes simplex virus 1 infection 💬
 1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
39 Herpes simplex virus 1 infection 💬
 1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
40 Herpes simplex virus 1 infection 💬
 1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
41 Herpes simplex virus 1 infection 💬
 2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
42 Herpes simplex virus 1 infection 💬
 1件: ITGA5 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
43 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
44 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
45 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
46 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
47 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
48 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
49 Herpes simplex virus 1 infection 💬
 1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
50 Herpes simplex virus 1 infection 💬
 2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
51 Herpes simplex virus 1 infection 💬
 2件: JAK1, JAK2 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
52 Herpes simplex virus 1 infection 💬
 2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
53 Herpes simplex virus 1 infection 💬
 2件: JAK1, JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
54 Herpes simplex virus 1 infection 💬
 3件: JAK1, JAK2, SYK 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
55 Herpes simplex virus 1 infection 💬
 3件: JAK1, JAK2, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
56 Herpes simplex virus 1 infection 💬
 3件: JAK1, JAK2, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
57 Herpes simplex virus 1 infection 💬
 3件: JAK1, JAK2, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
58 Herpes simplex virus 1 infection 💬
 3件: JAK1, JAK2, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
59 Herpes simplex virus 1 infection 💬
 1件: JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
60 Herpes simplex virus 1 infection 💬
 1件: LTA 💬 Pateclizumab 💬 Pateclizumab 1件: 46 💬
61 Herpes simplex virus 1 infection 💬
 2件: LTA, TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
62 Herpes simplex virus 1 infection 💬
 20件: MHC1, MHC1, MHC1, MHC1, MHC1, MHC1, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
63 Herpes simplex virus 1 infection 💬
 1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
64 Herpes simplex virus 1 infection 💬
 1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
65 Herpes simplex virus 1 infection 💬
 1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
66 Herpes simplex virus 1 infection 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
67 Herpes simplex virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
68 Herpes simplex virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
69 Herpes simplex virus 1 infection 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
70 Herpes simplex virus 1 infection 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
71 Herpes simplex virus 1 infection 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
72 Herpes simplex virus 1 infection 💬
 1件: PML 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
73 Herpes simplex virus 1 infection 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
74 Herpes simplex virus 1 infection 💬
 1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
75 Herpes simplex virus 1 infection 💬
 1件: SRC 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
76 Herpes simplex virus 1 infection 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
77 Herpes simplex virus 1 infection 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
78 Herpes simplex virus 1 infection 💬
 1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
79 Herpes simplex virus 1 infection 💬
 1件: SYK 💬 Fostamatinib 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
80 Herpes simplex virus 1 infection 💬
 1件: SYK 💬 Fostamatinib disodium 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
81 Herpes simplex virus 1 infection 💬
 1件: TLR9 💬 Cobitolimod 💬 Cobitolimod 1件: 97 💬
82 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
83 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
84 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
85 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
86 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
87 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
88 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
89 Herpes simplex virus 1 infection 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
90 Herpes simplex virus 1 infection 💬
 1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
91 Herpes simplex virus 1 infection 💬
 1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬