Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Benazepril hydrochloride 💬 Benazepril 4件: 49, 57, 218, 224 💬
2 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Benazepril 💬 Benazepril 4件: 49, 57, 218, 224 💬
3 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Captopril 💬 Captopril 7件: 17, 46, 86, 96, 97, 107, 271 💬
4 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Cilazapril 💬 Cilazapril 1件: 66 💬
5 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Cilazapril 💬 Cilazapril 1件: 66 💬
6 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Enalapril maleate 💬 Enalapril 8件: 13, 19, 46, 66, 113, 210, 222, 279 💬
7 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Enalapril 💬 Enalapril 8件: 13, 19, 46, 66, 113, 210, 222, 279 💬
8 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Imidapril hydrochloride 💬 Imidapril 1件: 67 💬
9 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Imidapril 💬 Imidapril 1件: 67 💬
10 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Lisinopril 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
11 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Lisinopril 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
12 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Moexipril hydrochloride 💬 Moexipril 1件: 93 💬
13 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Moexipril 💬 Moexipril 1件: 93 💬
14 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Perindopril erbumine 💬 Perindopril 4件: 58, 113, 167, 222 💬
15 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Perindopril 💬 Perindopril 4件: 58, 113, 167, 222 💬
16 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Perindopril arginine 💬 Perindopril 4件: 58, 113, 167, 222 💬
17 Coronavirus disease - COVID-19 💬
1件: ACE 💬 Ramipril 💬 Ramipril 7件: 46, 49, 66, 67, 113, 218, 257 💬
18 Coronavirus disease - COVID-19 💬
1件: ADAM17 💬 Apratastat 💬 Apratastat 1件: 46 💬
19 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
20 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
21 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
22 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil 1件: 66 💬
23 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil 1件: 66 💬
24 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil 1件: 66 💬
25 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Buloxibutid 💬 Buloxibutid 1件: 85 💬
26 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid 1件: 85 💬
27 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
28 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
29 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Losartan potassium 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
30 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Losartan 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
31 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
32 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
33 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 Valsartan 💬 Valsartan 8件: 57, 58, 66, 75, 86, 210, 222, 224 💬
34 Coronavirus disease - COVID-19 💬
2件: C1R, C1S 💬 Conestat alfa 💬 Conestat alfa 2件: 61, 65 💬
35 Coronavirus disease - COVID-19 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
36 Coronavirus disease - COVID-19 💬
1件: C1S 💬 Sutimlimab 💬 Sutimlimab 1件: 61 💬
37 Coronavirus disease - COVID-19 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
38 Coronavirus disease - COVID-19 💬
1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 222 💬
39 Coronavirus disease - COVID-19 💬
1件: C5 💬 Avacincaptad pegol sodium 💬 Avacincaptad pegol 1件: 301 💬
40 Coronavirus disease - COVID-19 💬
1件: C5 💬 Crovalimab 💬 Crovalimab 2件: 62, 109 💬
41 Coronavirus disease - COVID-19 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
42 Coronavirus disease - COVID-19 💬
1件: C5 💬 Gefurulimab 💬 Gefurulimab 1件: 11 💬
43 Coronavirus disease - COVID-19 💬
1件: C5 💬 Nomacopan 💬 Nomacopan 3件: 62, 109, 162 💬
44 Coronavirus disease - COVID-19 💬
1件: C5 💬 Pozelimab 💬 Pozelimab 3件: 11, 15, 62 💬
45 Coronavirus disease - COVID-19 💬
1件: C5 💬 Ravulizumab 💬 Ravulizumab 7件:  2 , 11, 13, 50, 62, 66, 109 💬
46 Coronavirus disease - COVID-19 💬
1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬
47 Coronavirus disease - COVID-19 💬
1件: C5 💬 Zilucoplan sodium 💬 Zilucoplan 2件: 11, 62 💬
48 Coronavirus disease - COVID-19 💬
1件: C5 💬 Zilucoplan 💬 Zilucoplan 2件: 11, 62 💬
49 Coronavirus disease - COVID-19 💬
1件: C5AR1 💬 Avacopan 💬 Avacopan 4件: 43, 44, 66, 222 💬
50 Coronavirus disease - COVID-19 💬
4件: CCL2, IL1B, IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
51 Coronavirus disease - COVID-19 💬
1件: CFB 💬 Iptacopan 💬 Iptacopan 6件: 11, 61, 62, 66, 109, 222 💬
52 Coronavirus disease - COVID-19 💬
1件: CFB 💬 Iptacopan hydrochloride 💬 Iptacopan 6件: 11, 61, 62, 66, 109, 222 💬
53 Coronavirus disease - COVID-19 💬
1件: CFD 💬 Danicopan 💬 Danicopan 2件: 62, 222 💬
54 Coronavirus disease - COVID-19 💬
1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
55 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
56 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
57 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
58 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
59 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
60 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
61 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
62 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
63 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
64 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
65 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
66 Coronavirus disease - COVID-19 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
67 Coronavirus disease - COVID-19 💬
1件: F2 💬 Dabigatran 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬
68 Coronavirus disease - COVID-19 💬
1件: F2 💬 Dabigatran etexilate mesylate 💬 Dabigatran etexilate 2件: 51, 75 💬
69 Coronavirus disease - COVID-19 💬
1件: F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate 2件: 51, 75 💬
70 Coronavirus disease - COVID-19 💬
1件: F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa 1件: 85 💬
71 Coronavirus disease - COVID-19 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
72 Coronavirus disease - COVID-19 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
73 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
74 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
75 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
76 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
77 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
78 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
79 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
80 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
81 Coronavirus disease - COVID-19 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
82 Coronavirus disease - COVID-19 💬
1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
83 Coronavirus disease - COVID-19 💬
2件: IL12A, IL12B 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
84 Coronavirus disease - COVID-19 💬
1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
85 Coronavirus disease - COVID-19 💬
1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
86 Coronavirus disease - COVID-19 💬
1件: IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
87 Coronavirus disease - COVID-19 💬
1件: IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
88 Coronavirus disease - COVID-19 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
89 Coronavirus disease - COVID-19 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
90 Coronavirus disease - COVID-19 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
91 Coronavirus disease - COVID-19 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
92 Coronavirus disease - COVID-19 💬
1件: IL6R 💬 Sarilumab 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬
93 Coronavirus disease - COVID-19 💬
1件: IL6R 💬 Satralizumab 💬 Satralizumab 4件: 11, 13, 86, 113 💬
94 Coronavirus disease - COVID-19 💬
1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 24件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
95 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
96 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
97 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
98 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
99 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
100 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
101 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
102 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
103 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
104 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
105 Coronavirus disease - COVID-19 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
106 Coronavirus disease - COVID-19 💬
2件: JAK1, SYK 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
107 Coronavirus disease - COVID-19 💬
2件: JAK1, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
108 Coronavirus disease - COVID-19 💬
2件: JAK1, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
109 Coronavirus disease - COVID-19 💬
2件: JAK1, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
110 Coronavirus disease - COVID-19 💬
2件: JAK1, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
111 Coronavirus disease - COVID-19 💬
1件: MASP2 💬 Narsoplimab 💬 Narsoplimab 2件: 66, 222 💬
112 Coronavirus disease - COVID-19 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
113 Coronavirus disease - COVID-19 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
114 Coronavirus disease - COVID-19 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
115 Coronavirus disease - COVID-19 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
116 Coronavirus disease - COVID-19 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
117 Coronavirus disease - COVID-19 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
118 Coronavirus disease - COVID-19 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
119 Coronavirus disease - COVID-19 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
120 Coronavirus disease - COVID-19 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
121 Coronavirus disease - COVID-19 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
122 Coronavirus disease - COVID-19 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
123 Coronavirus disease - COVID-19 💬
1件: SYK 💬 Fostamatinib 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
124 Coronavirus disease - COVID-19 💬
1件: SYK 💬 Fostamatinib disodium 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
125 Coronavirus disease - COVID-19 💬
1件: TLR7 💬 Imiquimod 💬 Imiquimod 2件: 34, 51 💬
126 Coronavirus disease - COVID-19 💬
2件: TLR7, TLR8 💬 Enpatoran 💬 Enpatoran 1件: 49 💬
127 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
128 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
129 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
130 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
131 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
132 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
133 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
134 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
135 Coronavirus disease - COVID-19 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
136 Coronavirus disease - COVID-19 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
137 Coronavirus disease - COVID-19 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬
138 Coronavirus disease - COVID-19 💬
1件: VWF 💬 Caplacizumab 💬 Caplacizumab 2件: 63, 64 💬