Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Pathways in cancer 💬
1件: ABL1 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
2 Pathways in cancer 💬
1件: ABL1 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
3 Pathways in cancer 💬
1件: ABL1 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
4 Pathways in cancer 💬
3件: ABL1, KIT, PDGFRA 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
5 Pathways in cancer 💬
3件: ABL1, KIT, PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
6 Pathways in cancer 💬
4件: ABL1, KIT, PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
7 Pathways in cancer 💬
3件: ABL1, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
8 Pathways in cancer 💬
3件: ABL1, KIT, PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
9 Pathways in cancer 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
10 Pathways in cancer 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
11 Pathways in cancer 💬
1件: AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
12 Pathways in cancer 💬
1件: AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil 1件: 66 💬
13 Pathways in cancer 💬
1件: AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil 1件: 66 💬
14 Pathways in cancer 💬
1件: AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil 1件: 66 💬
15 Pathways in cancer 💬
1件: AGTR1 💬 Buloxibutid 💬 Buloxibutid 1件: 85 💬
16 Pathways in cancer 💬
1件: AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid 1件: 85 💬
17 Pathways in cancer 💬
1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
18 Pathways in cancer 💬
1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
19 Pathways in cancer 💬
1件: AGTR1 💬 Losartan potassium 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
20 Pathways in cancer 💬
1件: AGTR1 💬 Losartan 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
21 Pathways in cancer 💬
1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
22 Pathways in cancer 💬
1件: AGTR1 💬 Valsartan 💬 Valsartan 8件: 57, 58, 66, 75, 86, 210, 222, 224 💬
23 Pathways in cancer 💬
2件: AGTR1, EDNRA 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
24 Pathways in cancer 💬
1件: ALK 💬 Brigatinib 💬 Brigatinib 1件: 34 💬
25 Pathways in cancer 💬
1件: ALK 💬 Crizotinib 💬 Crizotinib 2件:  2 , 34 💬
26 Pathways in cancer 💬
1件: AR 💬 Flutamide 💬 Flutamide 1件: 81 💬
27 Pathways in cancer 💬
1件: AR 💬 Nandrolone 💬 Nandrolone 2件: 60, 85 💬
28 Pathways in cancer 💬
1件: AR 💬 Nandrolone decanoate 💬 Nandrolone decanoate 2件: 60, 85 💬
29 Pathways in cancer 💬
1件: AR 💬 Oxandrolone 💬 Oxandrolone 2件: 211, 285 💬
30 Pathways in cancer 💬
1件: AR 💬 Stanozolol 💬 Stanozolol 1件: 60 💬
31 Pathways in cancer 💬
1件: AR 💬 Testosterone 💬 Testosterone 9件:  1 ,  2 ,  3 , 13, 60, 76, 78, 113, 265 💬
32 Pathways in cancer 💬
1件: AR 💬 Testosterone decanoate 💬 Testosterone decanoate 1件: 113 💬
33 Pathways in cancer 💬
1件: AR 💬 Testosterone enanthate 💬 Testosterone enanthate 1件: 113 💬
34 Pathways in cancer 💬
1件: AR 💬 Testosterone phenylpropionate 💬 Testosterone phenylpropionate 1件: 113 💬
35 Pathways in cancer 💬
1件: AR 💬 Testosterone propionate 💬 Testosterone propionate 1件: 113 💬
36 Pathways in cancer 💬
1件: AR 💬 Testosterone undecanoate 💬 Testosterone undecanoate 2件: 13, 60 💬
37 Pathways in cancer 💬
2件: AR, ESR1 💬 Danazol 💬 Danazol 5件: 60, 63, 64, 65, 285 💬
38 Pathways in cancer 💬
3件: AR, ESR1, ESR2 💬 Prasterone 💬 Prasterone 6件: 49, 53, 83, 86, 96, 113 💬
39 Pathways in cancer 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
40 Pathways in cancer 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
41 Pathways in cancer 💬
1件: BDKRB2 💬 Deucrictibant 💬 Deucrictibant 1件: 65 💬
42 Pathways in cancer 💬
1件: BDKRB2 💬 Icatibant acetate 💬 Icatibant 1件: 65 💬
43 Pathways in cancer 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
44 Pathways in cancer 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
45 Pathways in cancer 💬
7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
46 Pathways in cancer 💬
7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
47 Pathways in cancer 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
48 Pathways in cancer 💬
2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
49 Pathways in cancer 💬
1件: CSF1R 💬 Axatilimab 💬 Axatilimab 1件: 85 💬
50 Pathways in cancer 💬
7件: CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
51 Pathways in cancer 💬
7件: CSF1R, FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
52 Pathways in cancer 💬
1件: CSF2RA 💬 Mavrilimumab 💬 Mavrilimumab 2件: 41, 46 💬
53 Pathways in cancer 💬
1件: CSF2RA 💬 Molgramostim 💬 Molgramostim 2件: 229, 299 💬
54 Pathways in cancer 💬
1件: CSF2RA 💬 Regramostim 💬 Regramostim 1件: 229 💬
55 Pathways in cancer 💬
1件: CSF2RA 💬 Sargramostim 💬 Sargramostim 7件:  6 , 28, 60, 62, 96, 229, 285 💬
56 Pathways in cancer 💬
1件: CSF3R 💬 Filgrastim 💬 Filgrastim 29件:  2 ,  6 , 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
57 Pathways in cancer 💬
1件: CSF3R 💬 Lenograstim 💬 Lenograstim 8件:  2 , 13, 16, 18, 19, 57, 65, 97 💬
58 Pathways in cancer 💬
1件: CSF3R 💬 Pegfilgrastim 💬 Pegfilgrastim 1件: 60 💬
59 Pathways in cancer 💬
1件: CXCR4 💬 Mavorixafor 💬 Mavorixafor 1件: 65 💬
60 Pathways in cancer 💬
1件: CXCR4 💬 Plerixafor 💬 Plerixafor 5件: 20, 51, 65, 285, 299 💬
61 Pathways in cancer 💬
1件: EDNRA 💬 Ambrisentan 💬 Ambrisentan 8件: 51, 66, 84, 85, 86, 88, 210, 211 💬
62 Pathways in cancer 💬
1件: EDNRA 💬 Atrasentan hydrochloride 💬 Atrasentan 3件: 66, 218, 222 💬
63 Pathways in cancer 💬
1件: EDNRA 💬 Sitaxentan 💬 Sitaxentan 1件: 86 💬
64 Pathways in cancer 💬
1件: EDNRA 💬 Sitaxentan sodium 💬 Sitaxentan 1件: 86 💬
65 Pathways in cancer 💬
1件: EDNRA 💬 Zibotentan 💬 Zibotentan 1件: 51 💬
66 Pathways in cancer 💬
2件: EDNRA, EDNRB 💬 Bosentan 💬 Bosentan 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
67 Pathways in cancer 💬
2件: EDNRA, EDNRB 💬 Bosentan 💬 Bosentan 11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
68 Pathways in cancer 💬
2件: EDNRA, EDNRB 💬 Macitentan 💬 Macitentan 5件: 51, 85, 86, 88, 210 💬
69 Pathways in cancer 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
70 Pathways in cancer 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
71 Pathways in cancer 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
72 Pathways in cancer 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
73 Pathways in cancer 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
74 Pathways in cancer 💬
2件: EGFR, ERBB2 💬 Afatinib 💬 Afatinib 1件: 285 💬
75 Pathways in cancer 💬
2件: EGFR, ERBB2 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
76 Pathways in cancer 💬
2件: EGFR, ERBB2 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
77 Pathways in cancer 💬
2件: EGFR, ERBB2 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
78 Pathways in cancer 💬
2件: EGFR, ERBB2 💬 Neratinib 💬 Neratinib 1件: 34 💬
79 Pathways in cancer 💬
2件: EGFR, ERBB2 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
80 Pathways in cancer 💬
3件: EGFR, ERBB2, FLT4 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
81 Pathways in cancer 💬
1件: EPOR 💬 Epoetin beta 💬 Epoetin beta 2件: 13, 18 💬
82 Pathways in cancer 💬
1件: EPOR 💬 Epoetin alfa 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
83 Pathways in cancer 💬
1件: EPOR 💬 Epoetin epsilon 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
84 Pathways in cancer 💬
1件: EPOR 💬 Epoetin theta 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
85 Pathways in cancer 💬
1件: EPOR 💬 Epoetin zeta 💬 Erythropoietin 11件:  2 ,  6 , 13, 18, 22, 46, 47, 61, 70, 95, 96 💬
86 Pathways in cancer 💬
1件: EPOR 💬 Peginesatide 💬 Peginesatide 1件: 283 💬
87 Pathways in cancer 💬
1件: EPOR 💬 Peginesatide acetate 💬 Peginesatide 1件: 283 💬
88 Pathways in cancer 💬
1件: ESR1 💬 Desogestrel 💬 Desogestrel 1件: 230 💬
89 Pathways in cancer 💬
1件: ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol 4件: 13, 46, 49, 299 💬
90 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Bazedoxifene acetate 💬 Bazedoxifene 1件: 13 💬
91 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Clomiphene citrate 💬 Clomifene 2件: 74, 77 💬
92 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Clomifene 💬 Clomifene 2件: 74, 77 💬
93 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Estetrol 💬 Estetrol 1件: 53 💬
94 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Estetrol 💬 Estetrol 1件: 53 💬
95 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Estradiol 💬 Estradiol 3件: 13, 76, 299 💬
96 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Estradiol hemihydrate 💬 Estradiol 3件: 13, 76, 299 💬
97 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Estriol 💬 Estriol 2件: 13, 227 💬
98 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Estriol tripropionate 💬 Estriol 2件: 13, 227 💬
99 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Fulvestrant 💬 Fulvestrant 1件: 86 💬
100 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Raloxifene hydrochloride 💬 Raloxifene 2件: 46, 77 💬
101 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Raloxifene 💬 Raloxifene 2件: 46, 77 💬
102 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Tamoxifen citrate 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
103 Pathways in cancer 💬
2件: ESR1, ESR2 💬 Tamoxifen 💬 Tamoxifen 4件:  2 , 86, 113, 227 💬
104 Pathways in cancer 💬
1件: F2 💬 Dabigatran 💬 Dabigatran 5件: 51, 75, 85, 91, 124 💬
105 Pathways in cancer 💬
1件: F2 💬 Dabigatran etexilate mesylate 💬 Dabigatran etexilate 2件: 51, 75 💬
106 Pathways in cancer 💬
1件: F2 💬 Dabigatran etexilate 💬 Dabigatran etexilate 2件: 51, 75 💬
107 Pathways in cancer 💬
1件: F2 💬 Thrombomodulin alfa 💬 Thrombomodulin Alfa 1件: 85 💬
108 Pathways in cancer 💬
1件: FGF19 💬 Aldafermin 💬 Aldafermin 1件: 94 💬
109 Pathways in cancer 💬
1件: FGF23 💬 Burosumab 💬 Burosumab 1件: 238 💬
110 Pathways in cancer 💬
3件: FGFR1, FGFR2, FGFR3 💬 Infigratinib 💬 Infigratinib 1件: 276 💬
111 Pathways in cancer 💬
3件: FGFR1, FGFR2, FGFR3 💬 Infigratinib phosphate 💬 Infigratinib 1件: 276 💬
112 Pathways in cancer 💬
8件: FGFR1, FGFR2, FGFR3, FGFR4, FLT4, KIT, PDGFRA, PDGFRB 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
113 Pathways in cancer 💬
6件: FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
114 Pathways in cancer 💬
6件: FGFR1, FGFR2, FGFR3, FLT4, PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
115 Pathways in cancer 💬
1件: FGFR2 💬 Palifermin 💬 Palifermin 6件: 13, 36, 38, 39, 65, 96 💬
116 Pathways in cancer 💬
1件: FGFR3 💬 Recifercept 💬 Recifercept 1件: 276 💬
117 Pathways in cancer 💬
2件: FLT3, JAK2 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
118 Pathways in cancer 💬
1件: FLT4 💬 Axitinib 💬 Axitinib 1件: 34 💬
119 Pathways in cancer 💬
1件: FLT4 💬 Cediranib 💬 Cediranib 1件: 34 💬
120 Pathways in cancer 💬
1件: FLT4 💬 Cediranib maleate 💬 Cediranib 1件: 34 💬
121 Pathways in cancer 💬
4件: FLT4, KIT, PDGFRA, PDGFRB 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
122 Pathways in cancer 💬
2件: HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat 2件: 107, 113 💬
123 Pathways in cancer 💬
2件: HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
124 Pathways in cancer 💬
2件: HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat 1件: 75 💬
125 Pathways in cancer 💬
1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
126 Pathways in cancer 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
127 Pathways in cancer 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
128 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
129 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
130 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
131 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
132 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
133 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
134 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
135 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
136 Pathways in cancer 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
137 Pathways in cancer 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
138 Pathways in cancer 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
139 Pathways in cancer 💬
2件: IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b 7件: 18, 65, 85, 228, 299, 301, 326 💬
140 Pathways in cancer 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
141 Pathways in cancer 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
142 Pathways in cancer 💬
1件: IGF1R 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
143 Pathways in cancer 💬
3件: IL12A, IL12B, IL23A 💬 Ustekinumab 💬 Ustekinumab 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
144 Pathways in cancer 💬
1件: IL13 💬 Anrukinzumab 💬 Anrukinzumab 1件: 97 💬
145 Pathways in cancer 💬
1件: IL13 💬 Cendakimab 💬 Cendakimab 1件: 98 💬
146 Pathways in cancer 💬
1件: IL13 💬 Lebrikizumab 💬 Lebrikizumab 1件: 85 💬
147 Pathways in cancer 💬
1件: IL13 💬 Tralokinumab 💬 Tralokinumab 2件: 85, 97 💬
148 Pathways in cancer 💬
1件: IL23A 💬 Brazikumab 💬 Brazikumab 2件: 96, 97 💬
149 Pathways in cancer 💬
1件: IL23A 💬 Guselkumab 💬 Guselkumab 7件: 37, 41, 51, 96, 97, 161, 269 💬
150 Pathways in cancer 💬
1件: IL23A 💬 Mirikizumab 💬 Mirikizumab 3件: 37, 96, 97 💬
151 Pathways in cancer 💬
1件: IL23A 💬 Risankizumab 💬 Risankizumab 4件: 37, 96, 97, 271 💬
152 Pathways in cancer 💬
1件: IL23A 💬 Tildrakizumab 💬 Tildrakizumab 2件: 162, 271 💬
153 Pathways in cancer 💬
1件: IL2RA 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
154 Pathways in cancer 💬
1件: IL2RA 💬 Basiliximab 💬 Basiliximab 5件:  2 , 50, 97, 222, 228 💬
155 Pathways in cancer 💬
1件: IL2RA 💬 Daclizumab 💬 Daclizumab 8件: 13, 56, 60, 65, 97, 107, 283, 284 💬
156 Pathways in cancer 💬
3件: IL2RA, IL2RB, IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
157 Pathways in cancer 💬
1件: IL4R 💬 Dupilumab 💬 Dupilumab 5件: 51, 97, 98, 160, 162 💬
158 Pathways in cancer 💬
1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
159 Pathways in cancer 💬
1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
160 Pathways in cancer 💬
1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
161 Pathways in cancer 💬
1件: IL5RA 💬 Benralizumab 💬 Benralizumab 5件: 44, 45, 98, 162, 299 💬
162 Pathways in cancer 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
163 Pathways in cancer 💬
1件: IL6 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
164 Pathways in cancer 💬
1件: IL6 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
165 Pathways in cancer 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
166 Pathways in cancer 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
167 Pathways in cancer 💬
1件: IL6R 💬 Sarilumab 💬 Sarilumab 5件: 41, 46, 84, 107, 271 💬
168 Pathways in cancer 💬
1件: IL6R 💬 Satralizumab 💬 Satralizumab 4件: 11, 13, 86, 113 💬
169 Pathways in cancer 💬
1件: IL6R 💬 Tocilizumab 💬 Tocilizumab 24件:  2 , 11, 13, 40, 41, 42, 43, 44, 46, 49, 50, 51, 53, 54, 55, 56, 86, 107, 149, 153, 266, 271, 298, 331 💬
170 Pathways in cancer 💬
1件: IL7R 💬 Lusvertikimab 💬 Lusvertikimab 1件: 97 💬
171 Pathways in cancer 💬
1件: ITGB1 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
172 Pathways in cancer 💬
1件: ITGB1 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
173 Pathways in cancer 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
174 Pathways in cancer 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
175 Pathways in cancer 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
176 Pathways in cancer 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
177 Pathways in cancer 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
178 Pathways in cancer 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
179 Pathways in cancer 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
180 Pathways in cancer 💬
2件: JAK1, JAK2 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
181 Pathways in cancer 💬
2件: JAK1, JAK2 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
182 Pathways in cancer 💬
2件: JAK1, JAK2 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
183 Pathways in cancer 💬
3件: JAK1, JAK2, JAK3 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
184 Pathways in cancer 💬
3件: JAK1, JAK2, JAK3 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
185 Pathways in cancer 💬
3件: JAK1, JAK2, JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
186 Pathways in cancer 💬
3件: JAK1, JAK2, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
187 Pathways in cancer 💬
3件: JAK1, JAK2, JAK3 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
188 Pathways in cancer 💬
3件: JAK1, JAK2, JAK3 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
189 Pathways in cancer 💬
1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
190 Pathways in cancer 💬
1件: KIT 💬 Barzolvolimab 💬 Barzolvolimab 1件: 98 💬
191 Pathways in cancer 💬
1件: KIT 💬 Masitinib 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬
192 Pathways in cancer 💬
1件: KLHL19 💬 Dimethyl fumarate 💬 Dimethyl fumarate 6件: 13, 20, 49, 51, 86, 296 💬
193 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
194 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
195 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
196 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
197 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
198 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
199 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
200 Pathways in cancer 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
201 Pathways in cancer 💬
1件: MET 💬 Cabozantinib 💬 Cabozantinib 1件: 34 💬
202 Pathways in cancer 💬
1件: MET 💬 Cabozantinib s-malate 💬 Cabozantinib 1件: 34 💬
203 Pathways in cancer 💬
1件: MMP9 💬 Andecaliximab 💬 Andecaliximab 5件: 46, 96, 97, 272, 299 💬
204 Pathways in cancer 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
205 Pathways in cancer 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
206 Pathways in cancer 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
207 Pathways in cancer 💬
1件: NFE2L2 💬 Omaveloxolone 💬 Omaveloxolone 1件: 18 💬
208 Pathways in cancer 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
209 Pathways in cancer 💬
1件: NOS2 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
210 Pathways in cancer 💬
1件: NQO1 💬 Warfarin sodium 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
211 Pathways in cancer 💬
1件: NQO1 💬 Warfarin potassium 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
212 Pathways in cancer 💬
1件: NQO1 💬 Warfarin 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
213 Pathways in cancer 💬
2件: NR1C2, NR1C3 💬 Saroglitazar 💬 Saroglitazar 1件: 93 💬
214 Pathways in cancer 💬
2件: NR1C2, NR1C3 💬 Saroglitazar magnesium 💬 Saroglitazar 1件: 93 💬
215 Pathways in cancer 💬
1件: NR1C3 💬 Bocidelpar 💬 Bocidelpar 1件: 113 💬
216 Pathways in cancer 💬
1件: NR1C3 💬 Bocidelpar sulfate 💬 Bocidelpar 1件: 113 💬
217 Pathways in cancer 💬
1件: NR1C3 💬 Leriglitazone 💬 Leriglitazone 1件: 20 💬
218 Pathways in cancer 💬
1件: NR1C3 💬 Pioglitazone hydrochloride 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 220, 229, 265, 298, 299 💬
219 Pathways in cancer 💬
1件: NR1C3 💬 Pioglitazone 💬 Pioglitazone 17件:  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 81, 86, 96, 220, 229, 265, 298, 299 💬
220 Pathways in cancer 💬
1件: NR1C3 💬 Rosiglitazone maleate 💬 Rosiglitazone 6件: 46, 75, 77, 97, 222, 265 💬
221 Pathways in cancer 💬
1件: NR1C3 💬 Rosiglitazone 💬 Rosiglitazone 6件: 46, 75, 77, 97, 222, 265 💬
222 Pathways in cancer 💬
1件: NR1C3 💬 Seladelpar 💬 Seladelpar 2件: 93, 94 💬
223 Pathways in cancer 💬
1件: NR1C3 💬 Seladelpar lysine 💬 Seladelpar 2件: 93, 94 💬
224 Pathways in cancer 💬
2件: PDGFRA, PDGFRB 💬 Seralutinib 💬 Seralutinib 1件: 86 💬
225 Pathways in cancer 💬
3件: PGF, VEGFA, VEGFB 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬
226 Pathways in cancer 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
227 Pathways in cancer 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
228 Pathways in cancer 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
229 Pathways in cancer 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
230 Pathways in cancer 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
231 Pathways in cancer 💬
3件: PML, RARA, RARB 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
232 Pathways in cancer 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
233 Pathways in cancer 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
234 Pathways in cancer 💬
1件: PTGER1 💬 Alprostadil 💬 Alprostadil 2件: 51, 70 💬
235 Pathways in cancer 💬
1件: PTGER1 💬 Limaprost 💬 Limaprost 1件: 70 💬
236 Pathways in cancer 💬
3件: PTGER2, PTGER3, PTGER4 💬 Misoprostol 💬 Misoprostol 3件: 46, 70, 271 💬
237 Pathways in cancer 💬
1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
238 Pathways in cancer 💬
1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
239 Pathways in cancer 💬
1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
240 Pathways in cancer 💬
1件: PTGS2 💬 Celecoxib 💬 Celecoxib 14件:  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
241 Pathways in cancer 💬
1件: PTGS2 💬 Diclofenac potassium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
242 Pathways in cancer 💬
1件: PTGS2 💬 Diclofenac sodium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
243 Pathways in cancer 💬
1件: PTGS2 💬 Diclofenac 💬 Diclofenac 4件: 13, 34, 46, 271 💬
244 Pathways in cancer 💬
1件: PTGS2 💬 Diclofenac diethylamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
245 Pathways in cancer 💬
1件: PTGS2 💬 Diclofenac epolamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
246 Pathways in cancer 💬
1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
247 Pathways in cancer 💬
1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 3件: 46, 70, 271 💬
248 Pathways in cancer 💬
1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
249 Pathways in cancer 💬
1件: PTGS2 💬 Flurbiprofen sodium 💬 Flurbiprofen 3件: 13, 21, 46 💬
250 Pathways in cancer 💬
1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
251 Pathways in cancer 💬
1件: PTGS2 💬 Ibuprofen aluminum 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
252 Pathways in cancer 💬
1件: PTGS2 💬 Ibuprofen lysine 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
253 Pathways in cancer 💬
1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
254 Pathways in cancer 💬
1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
255 Pathways in cancer 💬
1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
256 Pathways in cancer 💬
1件: PTGS2 💬 Indomethacin sodium 💬 Indomethacin 3件: 225, 271, 298 💬
257 Pathways in cancer 💬
1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 2件: 13, 46 💬
258 Pathways in cancer 💬
1件: PTGS2 💬 Ketoprofen lysine 💬 Ketoprofen 2件: 13, 46 💬
259 Pathways in cancer 💬
1件: PTGS2 💬 Ketoprofen sodium 💬 Ketoprofen 2件: 13, 46 💬
260 Pathways in cancer 💬
1件: PTGS2 💬 Ketorolac tromethamine 💬 Ketorolac 2件: 70, 226 💬
261 Pathways in cancer 💬
1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
262 Pathways in cancer 💬
1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
263 Pathways in cancer 💬
1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
264 Pathways in cancer 💬
1件: PTGS2 💬 Meloxicam 💬 Meloxicam 3件: 46, 271, 296 💬
265 Pathways in cancer 💬
1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
266 Pathways in cancer 💬
1件: PTGS2 💬 Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
267 Pathways in cancer 💬
1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
268 Pathways in cancer 💬
1件: PTGS2 💬 Valdecoxib 💬 Parecoxib 2件: 46, 271 💬
269 Pathways in cancer 💬
1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
270 Pathways in cancer 💬
1件: PTGS2 💬 Parecoxib sodium 💬 Parecoxib 2件: 46, 271 💬
271 Pathways in cancer 💬
1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
272 Pathways in cancer 💬
1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
273 Pathways in cancer 💬
1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
274 Pathways in cancer 💬
1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
275 Pathways in cancer 💬
1件: RARA 💬 Tamibarotene 💬 Tamibarotene 3件: 26, 67, 96 💬
276 Pathways in cancer 💬
2件: RARA, RARB 💬 Fenretinide 💬 Fenretinide 1件: 299 💬
277 Pathways in cancer 💬
2件: RARA, RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
278 Pathways in cancer 💬
2件: RARA, RARB 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬
279 Pathways in cancer 💬
5件: RARA, RARB, RXRA, RXRB, RXRG 💬 Acitretin 💬 Acitretin 1件: 37 💬
280 Pathways in cancer 💬
5件: RARA, RARB, RXRA, RXRB, RXRG 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
281 Pathways in cancer 💬
3件: RARA, RARB, RXRB 💬 Tazarotene 💬 Tazarotene 1件: 85 💬
282 Pathways in cancer 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
283 Pathways in cancer 💬
2件: ROCK1, ROCK2 💬 Fasudil hydrochloride 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
284 Pathways in cancer 💬
2件: ROCK1, ROCK2 💬 Fasudil 💬 Fasudil 5件:  2 ,  5 ,  6 ,  7 , 51 💬
285 Pathways in cancer 💬
1件: ROCK2 💬 Belumosudil 💬 Belumosudil 3件: 51, 85, 228 💬
286 Pathways in cancer 💬
1件: ROCK2 💬 Belumosudil mesylate 💬 Belumosudil 3件: 51, 85, 228 💬
287 Pathways in cancer 💬
3件: RXRA, RXRB, RXRG 💬 Bexarotene 💬 Bexarotene 2件: 13, 75 💬
288 Pathways in cancer 💬
1件: SMO 💬 Taladegib 💬 Taladegib 1件: 85 💬
289 Pathways in cancer 💬
1件: SMO 💬 Vismodegib 💬 Vismodegib 1件: 85 💬
290 Pathways in cancer 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
291 Pathways in cancer 💬
1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 8件: 13, 34, 85, 87, 89, 227, 280, 331 💬
292 Pathways in cancer 💬
1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬