Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Glioma 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
2 Glioma 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
3 Glioma 💬
3件: BRAF, PDGFRB, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
4 Glioma 💬
3件: BRAF, PDGFRB, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
5 Glioma 💬
2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
6 Glioma 💬
1件: EGFR 💬 Afatinib 💬 Afatinib 1件: 285 💬
7 Glioma 💬
1件: EGFR 💬 Afatinib dimaleate 💬 Afatinib 1件: 285 💬
8 Glioma 💬
1件: EGFR 💬 Cetuximab 💬 Cetuximab 5件: 34, 51, 86, 89, 331 💬
9 Glioma 💬
1件: EGFR 💬 Erlotinib hydrochloride 💬 Erlotinib 2件: 94, 160 💬
10 Glioma 💬
1件: EGFR 💬 Erlotinib 💬 Erlotinib 2件: 94, 160 💬
11 Glioma 💬
1件: EGFR 💬 Gefitinib 💬 Gefitinib 1件: 75 💬
12 Glioma 💬
1件: EGFR 💬 Icotinib 💬 Icotinib 1件: 34 💬
13 Glioma 💬
1件: EGFR 💬 Lapatinib ditosylate 💬 Lapatinib 3件: 34, 74, 75 💬
14 Glioma 💬
1件: EGFR 💬 Lapatinib 💬 Lapatinib 3件: 34, 74, 75 💬
15 Glioma 💬
1件: EGFR 💬 Neratinib 💬 Neratinib 1件: 34 💬
16 Glioma 💬
1件: EGFR 💬 Neratinib maleate 💬 Neratinib 1件: 34 💬
17 Glioma 💬
1件: EGFR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
18 Glioma 💬
1件: IGF1R 💬 Linsitinib 💬 Linsitinib 1件: 232 💬
19 Glioma 💬
1件: IGF1R 💬 Mecasermin 💬 Mecasermin 4件: 96, 168, 265, 299 💬
20 Glioma 💬
1件: IGF1R 💬 Mecasermin rinfabate 💬 Mecasermin 4件: 96, 168, 265, 299 💬
21 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
22 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
23 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
24 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
25 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
26 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
27 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
28 Glioma 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
29 Glioma 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
30 Glioma 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
31 Glioma 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
32 Glioma 💬
1件: PDGFRA 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
33 Glioma 💬
1件: PDGFRA 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
34 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
35 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
36 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
37 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
38 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
39 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Seralutinib 💬 Seralutinib 1件: 86 💬
40 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
41 Glioma 💬
2件: PDGFRA, PDGFRB 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
42 Glioma 💬
1件: PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
43 Glioma 💬
1件: PDGFRB 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
44 Glioma 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
45 Glioma 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
46 Glioma 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
47 Glioma 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
48 Glioma 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
49 Glioma 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
50 Glioma 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬