Target Gene/Pathway Pathway / Gene
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No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
---|---|---|---|---|---|
1 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Bosutinib Bosutinib 💬
| Bosutinib | 002 2件: 2 , 67 💬
|
2 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Bosutinib hydrate Bosutinib hydrate 💬
| Bosutinib | 002 2件: 2 , 67 💬
|
3 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
4 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Dasatinib Dasatinib 💬
| Dasatinib | 051 2件: 51, 85 💬
|
5 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Imatinib mesylate Imatinib mesylate 💬
| Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
6 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Imatinib Imatinib 💬
| Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
|
7 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Nilotinib Nilotinib 💬
| Nilotinib | 006 5件: 6 , 8 , 34, 51, 86 💬
|
8 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
ABL1 1件: ABL1 💬
|
Saracatinib Saracatinib 💬
| Saracatinib | 006 3件: 6 , 89, 272 💬
|
9 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib Dabrafenib 💬
| Dabrafenib | 034 1件: 34 💬
|
10 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
BRAF 1件: BRAF 💬
|
Dabrafenib mesylate Dabrafenib mesylate 💬
| Dabrafenib | 034 1件: 34 💬
|
11 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib tosylate Sorafenib tosylate 💬
| Sorafenib | 034 2件: 34, 86 💬
|
12 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
BRAF 2件: BRAF, RAF1 💬
|
Sorafenib Sorafenib 💬
| Sorafenib | 034 2件: 34, 86 💬
|
13 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
CDK4 2件: CDK4, CDK6 💬
|
Abemaciclib Abemaciclib 💬
| Abemaciclib | 034 1件: 34 💬
|
14 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
HDAC1_2 2件: HDAC1_2, HDAC1_2 💬
|
Givinostat Givinostat 💬
| Givinostat | 107 2件: 107, 113 💬
|
15 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
HDAC1_2 2件: HDAC1_2, HDAC1_2 💬
|
Vorinostat Vorinostat 💬
| Vorinostat | 075 2件: 75, 96 💬
|
16 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
HDAC1_2 2件: HDAC1_2, HDAC1_2 💬
|
Fimepinostat Fimepinostat 💬
| Fimepinostat | 075 1件: 75 💬
|
17 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Binimetinib Binimetinib 💬
| Binimetinib | 034 1件: 34 💬
|
18 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib Cobimetinib 💬
| Cobimetinib | 280 1件: 280 💬
|
19 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Cobimetinib fumarate Cobimetinib fumarate 💬
| Cobimetinib | 280 1件: 280 💬
|
20 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Mirdametinib Mirdametinib 💬
| Mirdametinib | 034 4件: 34, 278, 279, 280 💬
|
21 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Selumetinib Selumetinib 💬
| Selumetinib | 034 1件: 34 💬
|
22 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Selumetinib sulfate Selumetinib sulfate 💬
| Selumetinib | 034 1件: 34 💬
|
23 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib Trametinib 💬
| Trametinib | 002 6件: 2 , 34, 58, 195, 279, 280 💬
|
24 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
MAP2K1 2件: MAP2K1, MAP2K2 💬
|
Trametinib dimethyl sulfoxide Trametinib dimethyl sulfoxide 💬
| Trametinib | 002 6件: 2 , 34, 58, 195, 279, 280 💬
|
25 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
NFKB1 1件: NFKB1 💬
|
Iguratimod Iguratimod 💬
| Iguratimod | 046 6件: 46, 49, 51, 53, 271, 300 💬
|
26 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
PIK3CA_B_D 1件: PIK3CA_B_D 💬
|
Alpelisib Alpelisib 💬
| Alpelisib | 138 4件: 138, 278, 279, 280 💬
|
27 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
PIK3CA_B_D 1件: PIK3CA_B_D 💬
|
Leniolisib phosphate Leniolisib phosphate 💬
| Leniolisib | 053 2件: 53, 65 💬
|
28 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
PIK3CA_B_D 1件: PIK3CA_B_D 💬
|
Parsaclisib Parsaclisib 💬
| Parsaclisib | 035 3件: 35, 53, 61 💬
|
29 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
PIK3CA_B_D 2件: PIK3CA_B_D, PIK3CA_B_D 💬
|
Copanlisib Copanlisib 💬
| Copanlisib | 121 1件: 121 💬
|
30 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
PIK3CA_B_D 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬
|
Leniolisib Leniolisib 💬
| Leniolisib | 053 2件: 53, 65 💬
|
31 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
RELA 1件: RELA 💬
|
Edasalonexent Edasalonexent 💬
| Edasalonexent | 113 1件: 113 💬
|
32 | Chronic myeloid leukemia 💬 17 genes, 23 drugs (DrugBank) and 36 diseases |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 4件: 51, 85, 222, 274 💬
|