Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Acute myeloid leukemia 💬
1件: BRAF 💬 Dabrafenib 💬 Dabrafenib 1件: 34 💬
2 Acute myeloid leukemia 💬
1件: BRAF 💬 Dabrafenib mesylate 💬 Dabrafenib 1件: 34 💬
3 Acute myeloid leukemia 💬
4件: BRAF, FLT3, KIT, RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
4 Acute myeloid leukemia 💬
4件: BRAF, FLT3, KIT, RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
5 Acute myeloid leukemia 💬
1件: CSF1R 💬 Axatilimab 💬 Axatilimab 1件: 85 💬
6 Acute myeloid leukemia 💬
3件: CSF1R, FLT3, KIT 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
7 Acute myeloid leukemia 💬
3件: CSF1R, FLT3, KIT 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
8 Acute myeloid leukemia 💬
1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
9 Acute myeloid leukemia 💬
1件: FLT3 💬 Pacritinib 💬 Pacritinib 1件: 331 💬
10 Acute myeloid leukemia 💬
1件: KIT 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
11 Acute myeloid leukemia 💬
1件: KIT 💬 Barzolvolimab 💬 Barzolvolimab 1件: 98 💬
12 Acute myeloid leukemia 💬
1件: KIT 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
13 Acute myeloid leukemia 💬
1件: KIT 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
14 Acute myeloid leukemia 💬
1件: KIT 💬 Imatinib mesylate 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
15 Acute myeloid leukemia 💬
1件: KIT 💬 Imatinib 💬 Imatinib 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬
16 Acute myeloid leukemia 💬
1件: KIT 💬 Masitinib 💬 Masitinib 6件:  2 ,  5 ,  6 , 13, 46, 96 💬
17 Acute myeloid leukemia 💬
1件: KIT 💬 Nilotinib 💬 Nilotinib 5件:  6 ,  8 , 34, 51, 86 💬
18 Acute myeloid leukemia 💬
1件: KIT 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
19 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
20 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
21 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
22 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
23 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
24 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
25 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
26 Acute myeloid leukemia 💬
2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
27 Acute myeloid leukemia 💬
1件: MPO 💬 Verdiperstat 💬 Verdiperstat 2件: 17, 127 💬
28 Acute myeloid leukemia 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
29 Acute myeloid leukemia 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
30 Acute myeloid leukemia 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
31 Acute myeloid leukemia 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
32 Acute myeloid leukemia 💬
1件: NR1C2 💬 Saroglitazar 💬 Saroglitazar 1件: 93 💬
33 Acute myeloid leukemia 💬
1件: NR1C2 💬 Saroglitazar magnesium 💬 Saroglitazar 1件: 93 💬
34 Acute myeloid leukemia 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
35 Acute myeloid leukemia 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
36 Acute myeloid leukemia 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
37 Acute myeloid leukemia 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
38 Acute myeloid leukemia 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
39 Acute myeloid leukemia 💬
2件: PML, RARA 💬 Tretinoin 💬 Tretinoin 6件:  2 , 62, 63, 75, 94, 231 💬
40 Acute myeloid leukemia 💬
1件: RARA 💬 Acitretin 💬 Acitretin 1件: 37 💬
41 Acute myeloid leukemia 💬
1件: RARA 💬 Alitretinoin 💬 Alitretinoin 1件: 49 💬
42 Acute myeloid leukemia 💬
1件: RARA 💬 Fenretinide 💬 Fenretinide 1件: 299 💬
43 Acute myeloid leukemia 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
44 Acute myeloid leukemia 💬
1件: RARA 💬 Tamibarotene 💬 Tamibarotene 3件: 26, 67, 96 💬
45 Acute myeloid leukemia 💬
1件: RARA 💬 Tazarotene 💬 Tazarotene 1件: 85 💬
46 Acute myeloid leukemia 💬
1件: RARA 💬 Vitamin A 💬 Vitamin A 3件: 13, 53, 90 💬
47 Acute myeloid leukemia 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬