Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Systemic lupus erythematosus 💬
2件: C1R, C1S 💬 Conestat alfa 💬 Conestat alfa 1件: 65 💬
2 Systemic lupus erythematosus 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
3 Systemic lupus erythematosus 💬
1件: C1S 💬 Sutimlimab 💬 Sutimlimab 1件: 61 💬
4 Systemic lupus erythematosus 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 3件: 11, 14, 50 💬
5 Systemic lupus erythematosus 💬
1件: C3 💬 Pegcetacoplan 💬 Pegcetacoplan 4件:  2 , 61, 62, 223 💬
6 Systemic lupus erythematosus 💬
1件: C5 💬 Avacincaptad pegol sodium 💬 Avacincaptad pegol 1件: 301 💬
7 Systemic lupus erythematosus 💬
1件: C5 💬 Crovalimab 💬 Crovalimab 3件: 48, 62, 109 💬
8 Systemic lupus erythematosus 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 223 💬
9 Systemic lupus erythematosus 💬
1件: C5 💬 Gefurulimab 💬 Gefurulimab 1件: 11 💬
10 Systemic lupus erythematosus 💬
1件: C5 💬 Nomacopan 💬 Nomacopan 1件: 162 💬
11 Systemic lupus erythematosus 💬
1件: C5 💬 Pozelimab 💬 Pozelimab 3件: 11, 15, 62 💬
12 Systemic lupus erythematosus 💬
1件: C5 💬 Ravulizumab 💬 Ravulizumab 8件:  2 , 11, 13, 50, 62, 66, 109, 224 💬
13 Systemic lupus erythematosus 💬
1件: C5 💬 Vilobelimab 💬 Vilobelimab 3件: 43, 44, 269 💬
14 Systemic lupus erythematosus 💬
1件: C5 💬 Zilucoplan sodium 💬 Zilucoplan 3件:  2 , 11, 62 💬
15 Systemic lupus erythematosus 💬
1件: C5 💬 Zilucoplan 💬 Zilucoplan 3件:  2 , 11, 62 💬
16 Systemic lupus erythematosus 💬
1件: CD28 💬 Acazicolcept 💬 Acazicolcept 1件: 49 💬
17 Systemic lupus erythematosus 💬
1件: CD40 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
18 Systemic lupus erythematosus 💬
1件: CD40 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
19 Systemic lupus erythematosus 💬
1件: CD40 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
20 Systemic lupus erythematosus 💬
1件: CD40LG 💬 Frexalimab 💬 Frexalimab 3件: 13, 222, 223 💬
21 Systemic lupus erythematosus 💬
2件: CD80, CD86 💬 Abatacept 💬 Abatacept 28件:  2 , 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 223, 271, 284, 285, 300 💬
22 Systemic lupus erythematosus 💬
2件: CD80, CD86 💬 Belatacept 💬 Belatacept 1件: 46 💬
23 Systemic lupus erythematosus 💬
1件: ELANE 💬 Depelestat 💬 Depelestat 1件: 299 💬
24 Systemic lupus erythematosus 💬
1件: ELANE 💬 Sivelestat 💬 Sivelestat 3件: 13, 85, 96 💬
25 Systemic lupus erythematosus 💬
1件: ELANE 💬 Ulinastatin 💬 Ulinastatin 1件: 70 💬
26 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Acamprosate calcium 💬 Acamprosate 3件:  2 ,  6 , 206 💬
27 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Acamprosate 💬 Acamprosate 3件:  2 ,  6 , 206 💬
28 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Amantadine hydrochloride 💬 Amantadine 5件:  2 ,  6 ,  8 , 13, 127 💬
29 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Amantadine 💬 Amantadine 5件:  2 ,  6 ,  8 , 13, 127 💬
30 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Dextromethorphan hydrobromide 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
31 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Dextromethorphan 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
32 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Dextromethorphan polistirex 💬 Dextromethorphan 10件:  2 ,  6 ,  8 , 13, 21, 46, 85, 96, 97, 156 💬
33 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Esketamine 💬 Esketamine 7件:  2 ,  4 ,  6 , 70, 96, 97, 156 💬
34 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Esketamine hydrochloride 💬 Esketamine 7件:  2 ,  4 ,  6 , 70, 96, 97, 156 💬
35 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Ketamine hydrochloride 💬 Ketamine 6件:  6 , 13, 70, 113, 156, 215 💬
36 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Ketamine 💬 Ketamine 6件:  6 , 13, 70, 113, 156, 215 💬
37 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Latrepirdine 💬 Latrepirdine 1件:  8  💬
38 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Latrepirdine dihydrochloride 💬 Latrepirdine 1件:  8  💬
39 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Memantine hydrochloride 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
40 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Memantine 💬 Memantine 8件:  2 ,  6 ,  8 , 13, 49, 127, 205, 206 💬
41 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Methadone hydrochloride 💬 Methadone 1件: 60 💬
42 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Methadone 💬 Methadone 1件: 60 💬
43 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Riluzole 💬 Riluzole 9件:  2 ,  3 ,  5 ,  8 , 13, 17, 18, 203, 206 💬
44 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Troriluzole 💬 Troriluzole 1件: 18 💬
45 Systemic lupus erythematosus 💬
2件: GRIN2A, GRIN2B 💬 Troriluzole hydrochloride 💬 Troriluzole 1件: 18 💬
46 Systemic lupus erythematosus 💬
1件: GRIN2B 💬 Radiprodil 💬 Radiprodil 3件: 137, 145, 158 💬
47 Systemic lupus erythematosus 💬
14件: HLA-DMA, HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPA1, HLA-DPB1, HLA-DQA1, HLA-DQA2, HLA-DQB1, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5 💬 Glatiramer acetate 💬 Glatiramer 4件:  2 , 13, 96, 156 💬
48 Systemic lupus erythematosus 💬
1件: IFNG 💬 Emapalumab 💬 Emapalumab 6件: 49, 50, 54, 60, 65, 107 💬
49 Systemic lupus erythematosus 💬
1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
50 Systemic lupus erythematosus 💬
2件: IL10, TNF 💬 Pirfenidone 💬 Pirfenidone 12件: 13, 34, 40, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
51 Systemic lupus erythematosus 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 22件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 90, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
52 Systemic lupus erythematosus 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 10件: 37, 40, 46, 48, 49, 96, 97, 107, 226, 271 💬
53 Systemic lupus erythematosus 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
54 Systemic lupus erythematosus 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
55 Systemic lupus erythematosus 💬
1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 162, 164, 223, 269, 270, 271 💬
56 Systemic lupus erythematosus 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 9件: 16, 26, 28, 34, 49, 56, 284, 300, 331 💬
57 Systemic lupus erythematosus 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
58 Systemic lupus erythematosus 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
59 Systemic lupus erythematosus 💬
1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
60 Systemic lupus erythematosus 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 22件:  2 , 16, 20, 28, 49, 51, 53, 56, 63, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬