Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
|---|---|---|---|---|---|
| 1 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CCL2 5件: CCL2, IL1A, IL1B, IL6, TNF 💬
|
Pirfenidone Pirfenidone 💬
| Pirfenidone | 013 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
|
| 2 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CD28 1件: CD28 💬
|
Acazicolcept Acazicolcept 💬
| Acazicolcept | 049 1件: 49 💬
|
| 3 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CD80 2件: CD80, CD86 💬
|
Abatacept Abatacept 💬
| Abatacept | 002 27件: 2 , 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
|
| 4 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CD80 2件: CD80, CD86 💬
|
Belatacept Belatacept 💬
| Belatacept | 046 1件: 46 💬
|
| 5 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CSF2 1件: CSF2 💬
|
Otilimab Otilimab 💬
| Otilimab | 046 1件: 46 💬
|
| 6 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CTLA4 1件: CTLA4 💬
|
Ipilimumab Ipilimumab 💬
| Ipilimumab | 159 1件: 159 💬
|
| 7 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
CTLA4 1件: CTLA4 💬
|
Tremelimumab Tremelimumab 💬
| Tremelimumab | 096 1件: 96 💬
|
| 8 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Catequentinib Catequentinib 💬
| Anlotinib | 085 1件: 85 💬
|
| 9 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Axitinib Axitinib 💬
| Axitinib | 034 1件: 34 💬
|
| 10 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Cediranib Cediranib 💬
| Cediranib | 034 1件: 34 💬
|
| 11 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Cediranib maleate Cediranib maleate 💬
| Cediranib | 034 1件: 34 💬
|
| 12 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Nintedanib esylate Nintedanib esylate 💬
| Nintedanib | 051 7件: 51, 84, 85, 89, 227, 228, 331 💬
|
| 13 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Nintedanib Nintedanib 💬
| Nintedanib | 051 7件: 51, 84, 85, 89, 227, 228, 331 💬
|
| 14 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Pazopanib hydrochloride Pazopanib hydrochloride 💬
| Pazopanib | 227 1件: 227 💬
|
| 15 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Sunitinib malate Sunitinib malate 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 16 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
FLT1 1件: FLT1 💬
|
Sunitinib Sunitinib 💬
| Sunitinib | 028 2件: 28, 34 💬
|
| 17 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
ICAM1 1件: ICAM1 💬
|
Alicaforsen sodium Alicaforsen sodium 💬
| Alicaforsen | 096 2件: 96, 97 💬
|
| 18 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IFNG 1件: IFNG 💬
|
Emapalumab Emapalumab 💬
| Emapalumab | 049 5件: 49, 54, 60, 65, 107 💬
|
| 19 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IFNG 1件: IFNG 💬
|
Fontolizumab Fontolizumab 💬
| Fontolizumab | 046 1件: 46 💬
|
| 20 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL17A 1件: IL17A 💬
|
Bimekizumab Bimekizumab 💬
| Bimekizumab | 037 5件: 37, 46, 97, 107, 271 💬
|
| 21 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL17A 1件: IL17A 💬
|
Ixekizumab Ixekizumab 💬
| Ixekizumab | 036 8件: 36, 37, 46, 107, 160, 162, 269, 271 💬
|
| 22 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL17A 1件: IL17A 💬
|
Secukinumab Secukinumab 💬
| Secukinumab | 013 8件: 13, 37, 41, 46, 107, 160, 269, 271 💬
|
| 23 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL17A 2件: IL17A, TNFSF13B 💬
|
Tibulizumab Tibulizumab 💬
| Tibulizumab | 051 2件: 51, 53 💬
|
| 24 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL1A 1件: IL1A 💬
|
Bermekimab Bermekimab 💬
| Bermekimab | 051 1件: 51 💬
|
| 25 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Lutikizumab Lutikizumab 💬
| Lutikizumab | 046 3件: 46, 96, 97 💬
|
| 26 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL1A 2件: IL1A, IL1B 💬
|
Rilonacept Rilonacept 💬
| Rilonacept | 051 5件: 51, 84, 106, 107, 266 💬
|
| 27 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬
|
Canakinumab Canakinumab 💬
| Canakinumab | 046 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
|
| 28 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL1B 1件: IL1B 💬
|
Gevokizumab Gevokizumab 💬
| Gevokizumab | 041 4件: 41, 50, 56, 269 💬
|
| 29 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL23A 1件: IL23A 💬
|
Brazikumab Brazikumab 💬
| Brazikumab | 096 2件: 96, 97 💬
|
| 30 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL23A 1件: IL23A 💬
|
Guselkumab Guselkumab 💬
| Guselkumab | 037 7件: 37, 41, 51, 96, 97, 161, 269 💬
|
| 31 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL23A 1件: IL23A 💬
|
Mirikizumab Mirikizumab 💬
| Mirikizumab | 037 3件: 37, 96, 97 💬
|
| 32 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL23A 1件: IL23A 💬
|
Risankizumab Risankizumab 💬
| Risankizumab | 037 4件: 37, 96, 97, 271 💬
|
| 33 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL23A 1件: IL23A 💬
|
Tildrakizumab Tildrakizumab 💬
| Tildrakizumab | 162 2件: 162, 271 💬
|
| 34 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL23A 1件: IL23A 💬
|
Ustekinumab Ustekinumab 💬
| Ustekinumab | 037 17件: 37, 40, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 160, 162, 269, 271 💬
|
| 35 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL6 1件: IL6 💬
|
Olokizumab Olokizumab 💬
| Olokizumab | 046 2件: 46, 96 💬
|
| 36 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL6 1件: IL6 💬
|
Siltuximab Siltuximab 💬
| Siltuximab | 028 2件: 28, 331 💬
|
| 37 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL6 1件: IL6 💬
|
Sirukumab Sirukumab 💬
| Sirukumab | 041 2件: 41, 46 💬
|
| 38 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
IL6 2件: IL6, TNF 💬
|
Pomalidomide Pomalidomide 💬
| Pomalidomide | 028 6件: 28, 34, 51, 85, 227, 331 💬
|
| 39 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
ITGAL 1件: ITGAL 💬
|
Anti-human thymocyte immunoglobulin, rabbit Anti-human thymocyte immunoglobulin, rabbit 💬
| Antithymocyte immunoglobulin (rabbit) | 013 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
|
| 40 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
ITGAL 1件: ITGAL 💬
|
Efalizumab Efalizumab 💬
| Efalizumab | 011 9件: 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
|
| 41 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
LTB 1件: LTB 💬
|
Baminercept Baminercept 💬
| Baminercept | 013 4件: 13, 46, 53, 97 💬
|
| 42 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
MHC2 14件: MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬
|
Glatiramer acetate Glatiramer acetate 💬
| Glatiramer | 013 3件: 13, 96, 156 💬
|
| 43 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TGFB1 3件: TGFB1, TGFB2, TGFB3 💬
|
Fresolimumab Fresolimumab 💬
| Fresolimumab | 051 4件: 51, 85, 222, 274 💬
|
| 44 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Adalimumab Adalimumab 💬
| Adalimumab | 019 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
|
| 45 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Certolizumab pegol Certolizumab pegol 💬
| Certolizumab pegol | 037 7件: 37, 46, 49, 96, 107, 226, 271 💬
|
| 46 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Etanercept Etanercept 💬
| Etanercept | 015 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
|
| 47 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Golimumab Golimumab 💬
| Golimumab | 046 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
|
| 48 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Infliximab Infliximab 💬
| Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
|
| 49 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Lenalidomide Lenalidomide 💬
| Lenalidomide | 016 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
|
| 50 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Ozoralizumab Ozoralizumab 💬
| Ozoralizumab | 046 1件: 46 💬
|
| 51 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Pegsunercept Pegsunercept 💬
| Pegsunercept | 046 1件: 46 💬
|
| 52 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNF 1件: TNF 💬
|
Thalidomide Thalidomide 💬
| Thalidomide | 002 21件: 2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
|
| 53 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF11 1件: TNFSF11 💬
|
Denosumab Denosumab 💬
| Denosumab | 046 10件: 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
|
| 54 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF13 1件: TNFSF13 💬
|
Sibeprenlimab Sibeprenlimab 💬
| Sibeprenlimab | 066 1件: 66 💬
|
| 55 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF13 1件: TNFSF13 💬
|
Zigakibart Zigakibart 💬
| Zigakibart | 066 1件: 66 💬
|
| 56 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF13 2件: TNFSF13, TNFSF13B 💬
|
Atacicept Atacicept 💬
| Atacicept | 013 5件: 13, 46, 49, 66, 222 💬
|
| 57 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬
|
Belimumab Belimumab 💬
| Belimumab | 011 14件: 11, 13, 43, 44, 46, 48, 49, 51, 53, 63, 66, 95, 222, 296 💬
|
| 58 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬
|
Rozibafusp alfa Rozibafusp alfa 💬
| Rozibafusp Alfa | 046 2件: 46, 49 💬
|
| 59 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
TNFSF13B 1件: TNFSF13B 💬
|
Tabalumab Tabalumab 💬
| Tabalumab | 046 2件: 46, 49 💬
|
| 60 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬
|
Aflibercept Aflibercept 💬
| Aflibercept | 090 2件: 90, 166 💬
|
| 61 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬
|
Bevacizumab Bevacizumab 💬
| Bevacizumab | 013 8件: 13, 34, 85, 87, 89, 227, 280, 331 💬
|
| 62 | Rheumatoid arthritis 💬 38 genes, 59 drugs (DrugBank) and 87 diseases |
VEGFA 1件: VEGFA 💬
|
Ranibizumab Ranibizumab 💬
| Ranibizumab | 034 4件: 34, 166, 227, 301 💬
|