Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Amiodarone hydrochloride 💬 Amiodarone 1件: 127 💬
2 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Amiodarone 💬 Amiodarone 1件: 127 💬
3 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Atenolol 💬 Atenolol 1件: 167 💬
4 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Bisoprolol fumarate 💬 Bisoprolol 4件: 58, 67, 86, 113 💬
5 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Bisoprolol 💬 Bisoprolol 4件: 58, 67, 86, 113 💬
6 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Carvedilol 💬 Carvedilol 6件:  6 , 46, 57, 86, 113, 210 💬
7 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Carvedilol phosphate 💬 Carvedilol 6件:  6 , 46, 57, 86, 113, 210 💬
8 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Celiprolol hydrochloride 💬 Celiprolol 1件: 168 💬
9 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Celiprolol 💬 Celiprolol 1件: 168 💬
10 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dipivefrin hydrochloride 💬 Dipivefrin 1件:  6  💬
11 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dipivefrin 💬 Dipivefrin 1件:  6  💬
12 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dobutamine hydrochloride 💬 Dobutamine 4件: 57, 58, 86, 215 💬
13 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dobutamine 💬 Dobutamine 4件: 57, 58, 86, 215 💬
14 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Dobutamine tartrate 💬 Dobutamine 4件: 57, 58, 86, 215 💬
15 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Droxidopa 💬 Droxidopa 5件:  5 ,  6 , 17, 169, 170 💬
16 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Ephedrine 💬 Ephedrine 1件: 11 💬
17 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Ephedrine hydrochloride 💬 Ephedrine 1件: 11 💬
18 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Ephedrine sulfate 💬 Ephedrine 1件: 11 💬
19 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Epinephrine 💬 Epinephrine 1件: 46 💬
20 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Epinephrine hydrochloride 💬 Epinephrine 1件: 46 💬
21 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Epinephrine bitartrate 💬 Epinephrine 1件: 46 💬
22 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Metoprolol tartrate 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
23 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Metoprolol succinate 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
24 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Metoprolol 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
25 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Metoprolol fumarate 💬 Metoprolol 6件: 17, 57, 58, 113, 193, 226 💬
26 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Nadolol 💬 Nadolol 1件:  6  💬
27 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Nebivolol 💬 Nebivolol 4件: 17, 85, 113, 167 💬
28 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Nebivolol hydrochloride 💬 Nebivolol 4件: 17, 85, 113, 167 💬
29 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Noradrenaline 💬 Norepinephrine 2件: 22, 296 💬
30 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Norepinephrine bitartrate 💬 Norepinephrine 2件: 22, 296 💬
31 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Norepinephrine hydrochoride 💬 Norepinephrine 2件: 22, 296 💬
32 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Propranolol hydrochloride 💬 Propranolol 7件:  6 , 158, 215, 216, 227, 278, 296 💬
33 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Propranolol 💬 Propranolol 7件:  6 , 158, 215, 216, 227, 278, 296 💬
34 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Pseudoephedrine hydrochloride 💬 Pseudoephedrine 1件: 17 💬
35 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Pseudoephedrine sulfate 💬 Pseudoephedrine 1件: 17 💬
36 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Pseudoephedrine 💬 Pseudoephedrine 1件: 17 💬
37 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Timolol 💬 Timolol 2件: 157, 227 💬
38 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Timolol maleate 💬 Timolol 2件: 157, 227 💬
39 Dilated cardiomyopathy 💬
1件: ADRB1 💬 Timolol 💬 Timolol 2件: 157, 227 💬
40 Dilated cardiomyopathy 💬
5件: ADRB1, CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Bevantolol hydrochloride 💬 Bevantolol 1件:  8  💬
41 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine besylate 💬 Amlodipine 3件: 51, 67, 298 💬
42 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine maleate 💬 Amlodipine 3件: 51, 67, 298 💬
43 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine 💬 Amlodipine 3件: 51, 67, 298 💬
44 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Amlodipine benzoate 💬 Amlodipine 3件: 51, 67, 298 💬
45 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Cilnidipine 💬 Cilnidipine 1件: 67 💬
46 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem hydrochloride 💬 Diltiazem 4件: 51, 58, 86, 88 💬
47 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem malate 💬 Diltiazem 4件: 51, 58, 86, 88 💬
48 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Diltiazem 💬 Diltiazem 4件: 51, 58, 86, 88 💬
49 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Isradipine 💬 Isradipine 1件:  6  💬
50 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine hydrochloride 💬 Nicardipine 2件: 70, 86 💬
51 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nicardipine 💬 Nicardipine 2件: 70, 86 💬
52 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nifedipine 💬 Nifedipine 1件: 81 💬
53 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Nilvadipine 💬 Nilvadipine 1件: 90 💬
54 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
55 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
56 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine hydrochloride 💬 Propiverine 1件: 226 💬
57 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Propiverine 💬 Propiverine 1件: 226 💬
58 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Topiramate 💬 Topiramate 5件:  6 , 140, 144, 156, 193 💬
59 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil hydrochloride 💬 Verapamil 4件: 58, 96, 140, 167 💬
60 Dilated cardiomyopathy 💬
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 Verapamil 💬 Verapamil 4件: 58, 96, 140, 167 💬
61 Dilated cardiomyopathy 💬
1件: CACNA1S 💬 Pinaverium bromide 💬 Pinaverium 1件: 298 💬
62 Dilated cardiomyopathy 💬
2件: CACNA2D1, CACNA2D2 💬 Mirogabalin 💬 Mirogabalin 1件: 70 💬
63 Dilated cardiomyopathy 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Gabapentin 💬 Gabapentin 5件:  6 , 13, 19, 70, 298 💬
64 Dilated cardiomyopathy 💬
4件: CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬 Pregabalin 💬 Pregabalin 5件: 13, 36, 46, 70, 298 💬
65 Dilated cardiomyopathy 💬
1件: DMD 💬 Casimersen 💬 Casimersen 1件: 113 💬
66 Dilated cardiomyopathy 💬
1件: DMD 💬 Delandistrogene moxeparvovec 💬 Delandistrogene moxeparvovec 1件: 113 💬
67 Dilated cardiomyopathy 💬
1件: DMD 💬 Drisapersen 💬 Drisapersen 1件: 113 💬
68 Dilated cardiomyopathy 💬
1件: DMD 💬 Eteplirsen 💬 Eteplirsen 1件: 113 💬
69 Dilated cardiomyopathy 💬
1件: DMD 💬 Golodirsen 💬 Golodirsen 1件: 113 💬
70 Dilated cardiomyopathy 💬
1件: DMD 💬 Viltolarsen 💬 Viltolarsen 1件: 113 💬
71 Dilated cardiomyopathy 💬
1件: ITGA4 💬 Firategrast 💬 Firategrast 1件: 13 💬
72 Dilated cardiomyopathy 💬
1件: ITGA4 💬 Natalizumab 💬 Natalizumab 5件: 13, 15, 25, 46, 96 💬
73 Dilated cardiomyopathy 💬
3件: ITGA4, ITGB1, ITGB7 💬 Carotegrast methyl 💬 Carotegrast methyl 1件: 97 💬
74 Dilated cardiomyopathy 💬
2件: ITGA4, ITGB7 💬 Abrilumab 💬 Abrilumab 2件: 96, 97 💬
75 Dilated cardiomyopathy 💬
2件: ITGA4, ITGB7 💬 Vedolizumab 💬 Vedolizumab 3件: 94, 96, 97 💬
76 Dilated cardiomyopathy 💬
3件: ITGA5, ITGB1, ITGB6 💬 Bexotegrast 💬 Bexotegrast 1件: 94 💬
77 Dilated cardiomyopathy 💬
1件: ITGB7 💬 Etrolizumab 💬 Etrolizumab 2件: 96, 97 💬
78 Dilated cardiomyopathy 💬
1件: MYH6_7 💬 Mavacamten 💬 Mavacamten 1件: 58 💬
79 Dilated cardiomyopathy 💬
4件: MYH6_7, MYH6_7, MYL2, MYL3 💬 Aficamten 💬 Aficamten 1件: 58 💬
80 Dilated cardiomyopathy 💬
1件: NOS1 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
81 Dilated cardiomyopathy 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬
82 Dilated cardiomyopathy 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
83 Dilated cardiomyopathy 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
84 Dilated cardiomyopathy 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
85 Dilated cardiomyopathy 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
86 Dilated cardiomyopathy 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
87 Dilated cardiomyopathy 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
88 Dilated cardiomyopathy 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
89 Dilated cardiomyopathy 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
90 Dilated cardiomyopathy 💬
1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
91 Dilated cardiomyopathy 💬
1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
92 Dilated cardiomyopathy 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬