Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Diabetic cardiomyopathy 💬
1件: ACE 💬 Benazepril hydrochloride 💬 Benazepril 4件: 49, 57, 218, 224 💬
2 Diabetic cardiomyopathy 💬
1件: ACE 💬 Benazepril 💬 Benazepril 4件: 49, 57, 218, 224 💬
3 Diabetic cardiomyopathy 💬
1件: ACE 💬 Captopril 💬 Captopril 7件: 17, 46, 86, 96, 97, 107, 271 💬
4 Diabetic cardiomyopathy 💬
1件: ACE 💬 Cilazapril 💬 Cilazapril 1件: 66 💬
5 Diabetic cardiomyopathy 💬
1件: ACE 💬 Cilazapril 💬 Cilazapril 1件: 66 💬
6 Diabetic cardiomyopathy 💬
1件: ACE 💬 Enalapril maleate 💬 Enalapril 8件: 13, 19, 46, 66, 113, 210, 222, 279 💬
7 Diabetic cardiomyopathy 💬
1件: ACE 💬 Enalapril 💬 Enalapril 8件: 13, 19, 46, 66, 113, 210, 222, 279 💬
8 Diabetic cardiomyopathy 💬
1件: ACE 💬 Imidapril hydrochloride 💬 Imidapril 1件: 67 💬
9 Diabetic cardiomyopathy 💬
1件: ACE 💬 Imidapril 💬 Imidapril 1件: 67 💬
10 Diabetic cardiomyopathy 💬
1件: ACE 💬 Lisinopril 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
11 Diabetic cardiomyopathy 💬
1件: ACE 💬 Lisinopril 💬 Lisinopril 7件: 19, 46, 49, 66, 67, 113, 222 💬
12 Diabetic cardiomyopathy 💬
1件: ACE 💬 Moexipril hydrochloride 💬 Moexipril 1件: 93 💬
13 Diabetic cardiomyopathy 💬
1件: ACE 💬 Moexipril 💬 Moexipril 1件: 93 💬
14 Diabetic cardiomyopathy 💬
1件: ACE 💬 Perindopril erbumine 💬 Perindopril 4件: 58, 113, 167, 222 💬
15 Diabetic cardiomyopathy 💬
1件: ACE 💬 Perindopril 💬 Perindopril 4件: 58, 113, 167, 222 💬
16 Diabetic cardiomyopathy 💬
1件: ACE 💬 Perindopril arginine 💬 Perindopril 4件: 58, 113, 167, 222 💬
17 Diabetic cardiomyopathy 💬
1件: ACE 💬 Ramipril 💬 Ramipril 7件: 46, 49, 66, 67, 113, 218, 257 💬
18 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
19 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Angiotensin II 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
20 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Angiotensin II acetate 💬 Angiotensin II 7件: 17, 46, 49, 66, 218, 222, 224 💬
21 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Azilsartan medoxomil 💬 Azilsartan medoxomil 1件: 66 💬
22 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Azilsartan 💬 Azilsartan medoxomil 1件: 66 💬
23 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Azilsartan kamedoxomil 💬 Azilsartan medoxomil 1件: 66 💬
24 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Buloxibutid 💬 Buloxibutid 1件: 85 💬
25 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Buloxibutid sodium 💬 Buloxibutid 1件: 85 💬
26 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Candesartan 💬 Candesartan 2件: 58, 67 💬
27 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Irbesartan 💬 Irbesartan 4件: 66, 167, 168, 222 💬
28 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Losartan potassium 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
29 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Losartan 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
30 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Sparsentan 💬 Sparsentan 3件: 66, 218, 222 💬
31 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Telmisartan 💬 Telmisartan 2件: 66, 67 💬
32 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 Valsartan 💬 Valsartan 8件: 57, 58, 66, 75, 86, 210, 222, 224 💬
33 Diabetic cardiomyopathy 💬
2件: CPT1B, CPT2 💬 Perhexiline maleate 💬 Perhexiline 2件: 58, 272 💬
34 Diabetic cardiomyopathy 💬
2件: CPT1B, CPT2 💬 Perhexiline 💬 Perhexiline 2件: 58, 272 💬
35 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin detemir 💬 Insulin detemir 1件: 299 💬
36 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin glargine 💬 Insulin glargine 1件: 299 💬
37 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin human 💬 Insulin human 1件: 156 💬
38 Diabetic cardiomyopathy 💬
1件: INSR 💬 Insulin lispro 💬 Insulin lispro 1件: 53 💬
39 Diabetic cardiomyopathy 💬
1件: MMP9 💬 Andecaliximab 💬 Andecaliximab 5件: 46, 96, 97, 272, 299 💬
40 Diabetic cardiomyopathy 💬
1件: MTOR 💬 Everolimus 💬 Everolimus 9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 💬
41 Diabetic cardiomyopathy 💬
1件: MTOR 💬 Sirolimus 💬 Sirolimus 46件:  2 ,  6 , 13, 15, 17, 19, 21, 34, 35, 36, 46, 48, 49, 51, 53, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 97, 98, 137, 157, 158, 192, 193, 222, 227, 256, 277, 278, 279, 280, 281, 283, 285, 300, 331 💬
42 Diabetic cardiomyopathy 💬
1件: MTOR 💬 Temsirolimus 💬 Temsirolimus 4件: 13, 34, 89, 331 💬
43 Diabetic cardiomyopathy 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
44 Diabetic cardiomyopathy 💬
1件: NOS3 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
45 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Bezafibrate 💬 Bezafibrate 8件: 20, 93, 94, 160, 296, 316, 324, 344 💬
46 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Elafibranor 💬 Elafibranor 2件: 93, 94 💬
47 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Fenofibrate 💬 Fenofibrate 6件:  8 , 79, 93, 94, 97, 265 💬
48 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Gemfibrozil 💬 Gemfibrozil 2件:  6 , 13 💬
49 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Pemafibrate 💬 Pemafibrate 1件: 93 💬
50 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Saroglitazar 💬 Saroglitazar 1件: 93 💬
51 Diabetic cardiomyopathy 💬
1件: NR1C1 💬 Saroglitazar magnesium 💬 Saroglitazar 1件: 93 💬
52 Diabetic cardiomyopathy 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
53 Diabetic cardiomyopathy 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
54 Diabetic cardiomyopathy 💬
1件: PARP1 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬
55 Diabetic cardiomyopathy 💬
3件: PDK2_3_4, PDK2_3_4, PDK2_3_4 💬 Sodium dichloroacetate 💬 Dichloroacetic acid 2件: 21, 86 💬
56 Diabetic cardiomyopathy 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
57 Diabetic cardiomyopathy 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
58 Diabetic cardiomyopathy 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
59 Diabetic cardiomyopathy 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
60 Diabetic cardiomyopathy 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
61 Diabetic cardiomyopathy 💬
1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
62 Diabetic cardiomyopathy 💬
1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
63 Diabetic cardiomyopathy 💬
1件: PRKCD 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
64 Diabetic cardiomyopathy 💬
1件: PRKCD 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
65 Diabetic cardiomyopathy 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
66 Diabetic cardiomyopathy 💬
1件: REN 💬 Aliskiren 💬 Aliskiren 3件: 66, 167, 222 💬
67 Diabetic cardiomyopathy 💬
1件: REN 💬 Aliskiren fumarate 💬 Aliskiren 3件: 66, 167, 222 💬
68 Diabetic cardiomyopathy 💬
3件: TGFB1, TGFB2, TGFB3 💬 Fresolimumab 💬 Fresolimumab 4件: 51, 85, 222, 274 💬