Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Fluid shear stress and atherosclerosis 💬
 1件: ACVR1 💬 Fidrisertib 💬 Fidrisertib 1件: 272 💬
2 Fluid shear stress and atherosclerosis 💬
 1件: ACVR1 💬 Zilurgisertib 💬 Zilurgisertib 1件: 272 💬
3 Fluid shear stress and atherosclerosis 💬
 1件: ACVR2A 💬 Sotatercept 💬 Sotatercept 2件: 86, 284 💬
4 Fluid shear stress and atherosclerosis 💬
 2件: ACVR2A, ACVR2B 💬 Bimagrumab 💬 Bimagrumab 1件: 15 💬
5 Fluid shear stress and atherosclerosis 💬
 1件: ACVR2B 💬 Luspatercept 💬 Luspatercept 3件: 60, 61, 282 💬
6 Fluid shear stress and atherosclerosis 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
7 Fluid shear stress and atherosclerosis 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
8 Fluid shear stress and atherosclerosis 💬
 4件: CCL2, IL1A, IL1B, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
9 Fluid shear stress and atherosclerosis 💬
 1件: HMOX1 💬 Stannsoporfin 💬 Stannsoporfin 1件: 254 💬
10 Fluid shear stress and atherosclerosis 💬
 1件: ICAM1 💬 Alicaforsen sodium 💬 Alicaforsen 2件: 96, 97 💬
11 Fluid shear stress and atherosclerosis 💬
 1件: IFNG 💬 Emapalumab 💬 Emapalumab 5件: 49, 54, 60, 65, 107 💬
12 Fluid shear stress and atherosclerosis 💬
 1件: IFNG 💬 Fontolizumab 💬 Fontolizumab 1件: 46 💬
13 Fluid shear stress and atherosclerosis 💬
 1件: IL1A 💬 Bermekimab 💬 Bermekimab 1件: 51 💬
14 Fluid shear stress and atherosclerosis 💬
 2件: IL1A, IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
15 Fluid shear stress and atherosclerosis 💬
 2件: IL1A, IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
16 Fluid shear stress and atherosclerosis 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
17 Fluid shear stress and atherosclerosis 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
18 Fluid shear stress and atherosclerosis 💬
 2件: IL1R1, IL1R2 💬 Anakinra 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
19 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Catequentinib 💬 Anlotinib 1件: 85 💬
20 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Axitinib 💬 Axitinib 1件: 34 💬
21 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Cabozantinib 💬 Cabozantinib 1件: 34 💬
22 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Cabozantinib s-malate 💬 Cabozantinib 1件: 34 💬
23 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Cediranib 💬 Cediranib 1件: 34 💬
24 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Cediranib maleate 💬 Cediranib 1件: 34 💬
25 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Nintedanib esylate 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
26 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Nintedanib 💬 Nintedanib 7件: 51, 84, 85, 89, 227, 228, 331 💬
27 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Pazopanib hydrochloride 💬 Pazopanib 1件: 227 💬
28 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
29 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
30 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Sunitinib malate 💬 Sunitinib 2件: 28, 34 💬
31 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Sunitinib 💬 Sunitinib 2件: 28, 34 💬
32 Fluid shear stress and atherosclerosis 💬
 1件: KDR 💬 Tesevatinib 💬 Tesevatinib 1件: 67 💬
33 Fluid shear stress and atherosclerosis 💬
 1件: KLHL19 💬 Dimethyl fumarate 💬 Dimethyl fumarate 6件: 13, 20, 49, 51, 86, 296 💬
34 Fluid shear stress and atherosclerosis 💬
 1件: MAP3K5 💬 Selonsertib 💬 Selonsertib 1件: 86 💬
35 Fluid shear stress and atherosclerosis 💬
 1件: MMP9 💬 Andecaliximab 💬 Andecaliximab 5件: 46, 96, 97, 272, 299 💬
36 Fluid shear stress and atherosclerosis 💬
 1件: NFE2L2 💬 Omaveloxolone 💬 Omaveloxolone 1件: 18 💬
37 Fluid shear stress and atherosclerosis 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
38 Fluid shear stress and atherosclerosis 💬
 1件: NOS3 💬 Tilarginine acetate 💬 Tilarginine 1件: 67 💬
39 Fluid shear stress and atherosclerosis 💬
 1件: NQO1 💬 Warfarin sodium 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
40 Fluid shear stress and atherosclerosis 💬
 1件: NQO1 💬 Warfarin potassium 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
41 Fluid shear stress and atherosclerosis 💬
 1件: NQO1 💬 Warfarin 💬 Warfarin 12件:  6 ,  8 , 19, 46, 49, 66, 85, 86, 88, 91, 96, 97 💬
42 Fluid shear stress and atherosclerosis 💬
 4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
43 Fluid shear stress and atherosclerosis 💬
 4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
44 Fluid shear stress and atherosclerosis 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
45 Fluid shear stress and atherosclerosis 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
46 Fluid shear stress and atherosclerosis 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
47 Fluid shear stress and atherosclerosis 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
48 Fluid shear stress and atherosclerosis 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
49 Fluid shear stress and atherosclerosis 💬
 1件: PLAT 💬 Aminocaproic acid 💬 Aminocaproic acid 1件: 70 💬
50 Fluid shear stress and atherosclerosis 💬
 2件: PRKAA, PRKAA 💬 Metformin hydrochloride 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
51 Fluid shear stress and atherosclerosis 💬
 2件: PRKAA, PRKAA 💬 Metformin 💬 Metformin 28件:  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 222, 225, 265, 285, 298, 299, 301 💬
52 Fluid shear stress and atherosclerosis 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
53 Fluid shear stress and atherosclerosis 💬
 1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
54 Fluid shear stress and atherosclerosis 💬
 1件: SRC 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
55 Fluid shear stress and atherosclerosis 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
56 Fluid shear stress and atherosclerosis 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
57 Fluid shear stress and atherosclerosis 💬
 1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
58 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
59 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
60 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
61 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
62 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
63 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
64 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
65 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
66 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
67 Fluid shear stress and atherosclerosis 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
68 Fluid shear stress and atherosclerosis 💬
 1件: VEGFA 💬 Aflibercept 💬 Aflibercept 2件: 90, 166 💬
69 Fluid shear stress and atherosclerosis 💬
 1件: VEGFA 💬 Bevacizumab 💬 Bevacizumab 8件: 13, 34, 85, 87, 89, 227, 280, 331 💬
70 Fluid shear stress and atherosclerosis 💬
 1件: VEGFA 💬 Ranibizumab 💬 Ranibizumab 4件: 34, 166, 227, 301 💬