Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(RS)-baclofen[1] Baclofen[1] Baclofen 💬 [2] GABBR1,
GABBR2 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 10 💬
2(RS)-baclofen, naltrexone hydrochloride and D-sorbitol[3] Baclofen,
Naltrexone,
Sorbitol		[4] Sorbitol solution ,
Baclofen ,
Naltrexone hydrochloride ,
Naltrexone 💬 		[5] GABBR1,
GABBR2,
OPRD1,
OPRK1,
OPRM1 💬 		[11] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, Taste transduction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 10 💬
3[PXT3003]----[1] 10 💬
4ACE-083----[2] 10, 113 💬
5Acetate[1] Acetate---[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬
6ACIDO ASCORBICO----[1] 10 💬
7ACIDO ASCORBICO DC.IT----[1] 10 💬
8Ascorbic acid[1] Ascorbic acid[1] Ascorbic acid 💬 --[4] 10, 97, 206, 298 💬
9Ascorbic acid (Vitamin C)[1] Ascorbic acid[1] Ascorbic acid 💬 --[1] 10 💬
10Ascorbic acid vit C[1] Ascorbic acid[1] Ascorbic acid 💬 --[1] 10 💬
11Baclofen[1] Baclofen[1] Baclofen 💬 [2] GABBR1,
GABBR2 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[8] 2, 10, 13, 18, 65, 70, 149, 206 💬
12BACLOFENE----[1] 10 💬
13BIOTIN[1] Biotin[1] Biotin 💬 --[6] 2, 8, 10, 13, 14, 20 💬
14Blood sample----[33] 2, 3, 6, 8, 10, 13, 14, 19, 34, 46, 48, 49, 51, 53, 61, 63, 65, 66, 67, 77, 79, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 299 💬
15CEBION 500*20CPR MAST 500MG----[1] 10 💬
16CEBION 500MG 20CPR MAST.ARAN----[1] 10 💬
17CLZ-2002[1] CLZ-2002---[1] 10 💬
18Coenzyme Q10----[11] 2, 5, 6, 8, 10, 18, 49, 57, 107, 113, 193 💬
19D-BIOTIN[1] Biotin[1] Biotin 💬 --[4] 10, 13, 14, 20 💬
20D-SORBITOL[1] Sorbitol[1] Sorbitol solution 💬 --[1] 10 💬
21Diagnostic Test: Bioimpedenziometry, Handgrip strenght evaluation----[1] 10 💬
22Diagnostic Test: Blood sample----[7] 10, 13, 49, 85, 271, 298, 299 💬
23Diagnostic Test: blood test for pro-inflammatory cytokines and ultrasound of the median nerves----[1] 10 💬
24Diagnostic Test: Evaluation on blood specimens----[1] 10 💬
25Diagnostic Test: NT3 blood draw----[2] 10, 14 💬
26Diagnostic Test: Skin biopsy----[1] 10 💬
27EDK060, dose A----[1] 10 💬
28EDK060, dose B----[1] 10 💬
29EDK060, dose C----[1] 10 💬
30EDK060, dose D----[1] 10 💬
31ElleOne----[1] 10 💬
32EN001----[2] 10, 113 💬
33Engensis (VM202)----[1] 10 💬
34Epalrestat[1] Epalrestat[1] Epalrestat 💬 [1] AKR1B1 💬 [5] Folate biosynthesis, Fructose and mannose metabolism, Galactose metabolism, Glycerolipid metabolism, Pentose and glucuronate interconversions 💬[1] 10 💬
35FLX-787-ODT (orally disintegrating tablet)----[1] 10 💬
36Genetic: ELP-02----[1] 10 💬
37Govorestat----[1] 10 💬
38Human Wharton's jelly-derived mesenchymal stem cells----[1] 10 💬
39MD1003----[5] 2, 10, 13, 14, 20 💬
40Mexiletine[1] Mexiletine[2] Mexiletine hydrochloride ,
Mexiletine 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[6] 1, 2, 10, 113, 114, 115 💬
41Naltrexone[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[14] 6, 10, 13, 40, 41, 42, 43, 44, 45, 46, 49, 96, 97, 226 💬
42NALTREXONE CLORIDRATO[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[1] 10 💬
43NALTREXONE HYDROCHLORIDE[1] Naltrexone[2] Naltrexone hydrochloride ,
Naltrexone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[9] 10, 40, 41, 42, 43, 44, 45, 96, 97 💬
44NL-GARS1-001----[1] 10 💬
45NMD670----[3] 3, 10, 11 💬
46Non applicable----[2] 10, 19 💬
47Other: Berg Balance Scale (BBS)----[1] 10 💬
48Other: blood samples analysis----[1] 10 💬
49Other: Blood test----[11] 10, 19, 46, 51, 57, 65, 66, 83, 86, 96, 113 💬
50Other: Clinical evaluation----[2] 2, 10 💬
51Other: Clinical scores----[1] 10 💬
52Other: electrophysiological record----[1] 10 💬
53Other: Muscle MRI----[2] 3, 10 💬
54Other: Patient Report Outcomes Measures----[1] 10 💬
55Other: Posturological examination on KPlates and AMTI platforms----[1] 10 💬
56Other: Quantitative neuromuscular MRI----[1] 10 💬
57Other: Skin biopsy----[1] 10 💬
58PXT3003----[1] 10 💬
59PXT3003 Dose 1----[1] 10 💬
60PXT3003 Dose 2----[1] 10 💬
61PXT3003 Dose 2 (equivalent to twice Dose 1)----[1] 10 💬
62PXT3003 High Dose----[1] 10 💬
63PXT3003 Intermediate Dose----[1] 10 💬
64PXT3003 Low dose----[1] 10 💬
65RS-BACLOFEN[1] Baclofen[1] Baclofen 💬 [2] GABBR1,
GABBR2 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[1] 10 💬
66SODIO ASCORBATO DC.IT----[1] 10 💬
67Sorbitol[1] Sorbitol[1] Sorbitol solution 💬 --[2] 10, 97 💬
68SORBITOLO----[1] 10 💬
69Ulipristal[1] Ulipristal[2] Ulipristal ,
Ulipristal acetate 💬 		[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 10 💬
70ULIPRISTAL ACETATE[2] Acetate,
Ulipristal		[2] Ulipristal ,
Ulipristal acetate 💬 		[1] PGR 💬 [5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 10 💬
71VCA-894A[1] VCA-894A---[1] 10 💬