What is DDrare?
News
| Jun 17, 2026 | The website is now back online. We apologize for any inconvenience caused. |
|---|---|
| Dec 5, 2025 | DDrare was published in the special issue of Jikken Igaku (Vol.43 No.20) (in Japanese). |
| Dec 5, 2025 | Poster presentation at The 48th Annual Meeting of the Molecular Biology Society of Japan: DDrare ~ Database of Drug Development for Rare and Intractable Diseases ~］ |
| Nov 26, 2025 | Med expenses recipients data was updated to FY2024. |
| Oct 20, 2025 | Poster presentation at NBDC TOGO symposium: DDrare: A Comprehensive Database of Clinical Trials, Investigational Drugs, and Target Genes and Pathways for Rare and Intractable Diseases (in Japanese) |
| Aug 27, 2025 | Data ver. Aug2025. Previous version is here. |
| Jul 8, 2025 | DDrare's sister site, Nanbyo Chiken Web (in Japanese), was launched. It provides easy-to-understand information on rare disease clinical trials in Japan. |
| Jul 4, 2025 | Clinical research form in Disease details was updated to FY2025. |
| Jun 25, 2025 | Med expenses recipients data was updated to FY2023. |
| May 14, 2025 | Changed multiple word search from OR search to AND search. Other small improvements have been made. |
| Apr 1, 2025 | The URL for DDrare has changed from ddrare.nibiohn.go.jp to ddrare.nibn.go.jp. |
| Feb 18, 2025 | Link to DDrare was added in NAN-COMMU: Rare disease information exchange site (in Japanese). |
| Sep 10, 2024 | DDrare was published in BIO Clinica 39/10, Sep.2024 issue (in Japanese). |
| Jan 25, 2024 | DDrare was published in Precision Medicine, Feb. 2024 issue: Methodological innovations in clinical trials and observational studies (in Japanese). |
| Nov 18, 2022 | Link to DDrare was added in WHO ICTRP search portal. |
| Oct 25-29, 2022 | Poster presentation at ASHG 2022: PB2035. Drug repositioning network in rare and intractable diseases based on drug target gene analyses. |
| Oct 5, 2022 | Poster presentation at NBDC TOGO symposium (in Japanese): DDrare Update - Database of Drug Development for Rare Diseases - |
| Sep 28, 2021 | DDrare ~ Database of developing drugs, target genes and pathways for rare diseases ~ is added to References. |
| Jun 11, 2021 | Our paper "Drug Target Gene-based Analyses of Drug Repositionability in Rare and Intractable Diseases." was published. |
| Sep 25, 2020 | DDrare - Database of developing drugs, target genes and pathways for rare diseases - is added to References. |
| Jun 22, 2020 | English version has opened. |
| Mar 30, 2018 | Newly open to public. |
Features
Information of Drug Development extracted from Clinical Trials Data
Drugs are extracted from clinical trials data for the intractable diseases (mostly rare diseases) designated by MHLW, Japan.
Clinical Trials for Rare and Intractable Diseases in Four Major Registries
Comprehensive information is available from the World’s four major clinical trial registries of US, EU, China and Japan.
Cross-Reference information for Drug Development
Among Diseases, Drugs, and Target Genes/Pathways, cross-reference is available for target discovery in drug development.
Statistics
Diseases
Clinical Trials
Drugs
Target Genes
Target Pathways
Data Sources / References
- MHLW Intractable Diseases (in Japanese)
Referred in Jul 2025 - Japan Intractable Diseases Information Center
(in Japanese)
Referred in Jul 2025 - DrugBank
Release Version 5.1.13 (Jan 2025) - KEGG
Referred in Jul 2025
Disclaimer
The information on this website is provided for research purposes only and does not replace the advice or consultation of a doctor. In principle, all rights relating to the information on this website belong to National Institutes of Biomedical Innovation, Health and Nutrition. Please contact us in advance if you would like to use the information on this website. Information on this website is subject to change without notice. In any case, we will not be liable for any damages arising from the use of the information on this website.