| 1 | [ALN-62643] | - | - | - | - | [1] 109 109 💬
|
| 2 | [RO7112689/F03-01] | - | - | - | - | [1] 109 109 💬
|
| 3 | [RO7112689/F03-10] | - | - | - | - | [1] 109 109 💬
|
| 4 | ALN-CC5 | - | - | - | - | [4] 11 11, 62, 66, 109 💬
|
| 5 | ALXN1210 | - | - | - | - | [7] 2 2, 11, 13, 50, 62, 66, 109 💬
|
| 6 | Anti-C5 antibody | - | - | - | - | [4] 11 11, 14, 62, 109 💬
|
| 7 | C5 inh MAb, SKY59, RO/CH7092230 | - | - | - | - | [2] 62 62, 109 💬
|
| 8 | CCX168 | - | - | - | - | [6] 43 43, 44, 49, 66, 109, 223 💬
|
| 9 | Cemdisiran | [1] Cemdisiran Cemdisiran | - | - | - | [6] 11 11, 15, 62, 66, 109, 223 💬
|
| 10 | COVERSIN | - | - | - | - | [2] 62 62, 109 💬
|
| 11 | Crovalimab | [1] Crovalimab Crovalimab | [1] Crovalimab
Crovalimab
💬
| [1] C5 C5 💬
| [11] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | [3] 48 48, 62, 109 💬
|
| 12 | CrovalimabProduct Code: RO7112689/F03-10Pharmaceutical Form: Solution for injection/infusionINN or Proposed INN: CROVALIMABCurrent Sponsor code: RO7112689Other descriptive name: C5 inh MAb, SKY59, RO/CH7092230Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 170-Product Name: CrovalimabProduct Code: RO7112689/F03-01Pharmaceutical Form: Solution for injection/infusionINN or Proposed INN: CROVALIMABCurrent Sponsor code: RO7112689Other descriptive name: C5 inh MAb, SKY59, RO/CH7092230Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 170- | - | - | - | - | [1] 109 109 💬
|
| 13 | ECULIZUMAB | [1] Eculizumab Eculizumab | [1] Eculizumab
Eculizumab
💬
| [1] C5 C5 💬
| [11] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | [8] 11 11, 13, 14, 61, 62, 109, 221, 223 💬
|
| 14 | Fc- and CDR-modified humanised monoclonal antibody against C5 | - | - | - | - | [3] 11 11, 62, 109 💬
|
| 15 | IgG2/4? | - | - | - | - | [1] 109 109 💬
|
| 16 | Iptacopan | [1] Iptacopan Iptacopan | [2] Iptacopan
Iptacopan
,
Iptacopan hydrochloride
💬
| [1] CFB CFB 💬
| [3] Complement and coagulation cascades Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬 | [8] 11 11, 61, 62, 63, 66, 109, 222, 223 💬
|
| 17 | Iptacopan hydrochloride | [1] Iptacopan Iptacopan | [2] Iptacopan
Iptacopan
,
Iptacopan hydrochloride
💬
| [1] CFB CFB 💬
| [3] Complement and coagulation cascades Complement and coagulation cascades, Coronavirus disease, Staphylococcus aureus infection 💬 | [5] 61 61, 63, 66, 109, 223 💬
|
| 18 | Iptcaopan 200 mg | - | - | - | - | [1] 109 109 💬
|
| 19 | LNP023 | - | - | - | - | [7] 61 61, 62, 63, 66, 109, 222, 223 💬
|
| 20 | NM8074 | - | - | - | - | [5] 50 50, 62, 66, 109, 223 💬
|
| 21 | OMS00620646, OMS620646, MASP-2 Antibody | - | - | - | - | [1] 109 109 💬
|
| 22 | OMS721 | - | - | - | - | [3] 64 64, 66, 109 💬
|
| 23 | OMS721 100 mg/ml Injection solution, OMS00620646, OMS620646, MASP-2 Antibody | - | - | - | - | [2] 64 64, 109 💬
|
| 24 | OMS721 185 mg/ml Injection solution, OMS00620646, OMS620646, MASP-2 Antibody | - | - | - | - | [2] 64 64, 109 💬
|
| 25 | OMS721 Drug Product 185 mg/mL | - | - | - | - | [1] 109 109 💬
|
| 26 | Other: Blood sampling and urine analysis | - | - | - | - | [1] 109 109 💬
|
| 27 | Other: Eculizumab | [1] Eculizumab Eculizumab | [1] Eculizumab
Eculizumab
💬
| [1] C5 C5 💬
| [11] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | [1] 109 109 💬
|
| 28 | RAVULIZUMAB | [1] Ravulizumab Ravulizumab | [1] Ravulizumab
Ravulizumab
💬
| [1] C5 C5 💬
| [11] Alcoholic liver disease Alcoholic liver disease, Complement and coagulation cascades, Coronavirus disease, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Neutrophil extracellular trap formation, Pertussis, Prion disease, Regulation of actin cytoskeleton, Staphylococcus aureus infection, Systemic lupus erythematosus 💬 | [8] 2 2, 11, 13, 50, 62, 66, 109, 224 💬
|
| 29 | RO7112689/F03-01 | - | - | - | - | [2] 62 62, 109 💬
|
| 30 | RO7112689/F03-10 | - | - | - | - | [2] 62 62, 109 💬
|
| 31 | RVA576 | - | - | - | - | [3] 62 62, 109, 162 💬
|
| 32 | RVA576 (COVERSIN) | - | - | - | - | [2] 62 62, 109 💬
|
| 33 | Solaris | - | - | - | - | [2] 62 62, 109 💬
|
| 34 | SOLIRIS | - | - | - | - | [6] 11 11, 13, 14, 62, 109, 223 💬
|
| 35 | SOLIRIS - 300 MG CONCENTRATO PER SOLUZIONE PER INFUSIONE - USO ENDOVENOSO 1 FLACONCINO (VETRO) 30 ML (10 MG/ML) | - | - | - | - | [3] 13 13, 62, 109 💬
|
| 36 | SOLIRIS 300 mg concentrado para solución para perfusión | - | - | - | - | [1] 109 109 💬
|
| 37 | Soliris 300 mg solution à diluer pour perfusion | - | - | - | - | [1] 109 109 💬
|
| 38 | Ultomiris | - | - | - | - | [7] 2 2, 11, 13, 50, 62, 66, 109 💬
|
| 39 | LNP023 HYDROCHLORIDE SALT | - | - | - | - | [7] 61 61, 62, 63, 66, 109, 222, 223 💬
|