Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
112-Lead ECG----[2] 140, 144 💬
2[TAK-935]----[2] 140, 144 💬
3[YKP509]----[1] 144 💬
4[ZX008]----[2] 140, 144 💬
5Any other approved Antiepileptic Drug----[1] 144 💬
6Bexicaserin[1] Bexicaserin[1] Bexicaserin 💬 [1] HTR2C 💬 [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[2] 140, 144 💬
7BMB-101----[3] 140, 144, 193 💬
8Cannabidiol[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[20] 6, 8, 13, 19, 36, 46, 51, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬
9Cannabidiol (CBD)[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[7] 6, 13, 140, 144, 145, 156, 158 💬
10Cannabidiol Oral Solution[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[4] 140, 144, 145, 193 💬
11CARISBAMATE[1] Carisbamate[1] Carisbamate 💬 --[1] 144 💬
12Carisbamate (S)-2-O-carbamoyl-1-o-chlorophenyl-ethanol[2] Carisbamate,
Ethanol		[3] Alcohol ,
Ethanol ,
Carisbamate 💬 		--[1] 144 💬
13CBD - Oral Solution, is known as Epidiolex, and is the approved name in the USA.----[2] 140, 144 💬
14CBD: GT4 Transdermal Delivery System----[2] 140, 144 💬
15Clemizole[1] Clemizole[2] Clemizole hydrochloride ,
Clemizole 💬 		[1] TRPC5 💬 [2] Axon guidance, GnRH secretion 💬[2] 140, 144 💬
16Clemizole HCl[1] Clemizole[2] Clemizole hydrochloride ,
Clemizole 💬 		[1] TRPC5 💬 [2] Axon guidance, GnRH secretion 💬[2] 140, 144 💬
17Clobazam[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 140, 144 💬
18Clobazam High Dose[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
19Clobazam Low Dose[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
20Clobazam Medium Dose[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
21Clobazam PhEur[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
22Clobazam Tablets[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
23Clobazam Tablets 10mg[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
24Clobazam Tablets 20mg[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
25Clobazam Tablets 5mg[1] Clobazam[1] Clobazam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[1] 144 💬
26E2007----[2] 6, 144 💬
27E2080----[1] 144 💬
28Epidiolex 100 mg/mL Oral Solution----[3] 140, 144, 158 💬
29Ethanol[1] Ethanol[2] Alcohol ,
Ethanol 💬 		--[8] 51, 58, 97, 144, 214, 278, 279, 280 💬
30Ezogabine[1] Ezogabine[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144 💬
31EZOGABINE (US ONLY)[1] Ezogabine[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[1] 144 💬
32Ezogabine/retigabine[1] Ezogabine[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[1] 144 💬
33Fenfluramina Cloridrato[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[2] 140, 144 💬
34FENFLURAMINE[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[6] 140, 143, 144, 145, 149, 156 💬
35Fenfluramine HCl[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[1] 144 💬
36Fenfluramine HCl, DL-Fenfluramine, (±)-Fenfluramine[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[1] 144 💬
37FENFLURAMINE HYDROCHLORIDE[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[4] 140, 143, 144, 156 💬
38FENFLURAMINE HYDROCHLORIDE (colorless)[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[2] 140, 144 💬
39Fycompa----[2] 2, 144 💬
40GW582892----[1] 144 💬
41GWP42003-P----[6] 140, 143, 144, 145, 156, 158 💬
42GWP42003-P 20 mg/kg/day Dose----[2] 140, 144 💬
43Inovelon----[1] 144 💬
44Investigators Choice of Approved AED----[1] 144 💬
45Investigators choice of approved AEDs----[1] 144 💬
46Lamictal----[1] 144 💬
47Lamotrigine[1] Lamotrigine[1] Lamotrigine 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[7] 13, 34, 38, 113, 114, 115, 144 💬
48LP352----[2] 140, 144 💬
49LP352, bexicaserin[1] Bexicaserin[1] Bexicaserin 💬 [1] HTR2C 💬 [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[2] 140, 144 💬
50Perampanel[1] Perampanel[2] Perampanel ,
Perampanel hydrate 💬 		[4] GRIA1,
GRIA2,
GRIA3,
GRIA4 💬 		[17] Amphetamine addiction, Amyotrophic lateral sclerosis, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[3] 2, 6, 144 💬
51Potiga----[1] 144 💬
52RETIGABINE[1] Ezogabine[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[2] 2, 144 💬
53RETIGABINE/EZOGABINE[1] Ezogabine[1] Ezogabine 💬 [5] KCNQ1,
KCNQ2,
KCNQ3,
KCNQ4,
KCNQ5 💬 		[7] Adrenergic signaling in cardiomyocytes, Cholinergic synapse, Gastric acid secretion, IgSF CAM signaling, Pancreatic secretion, Protein digestion and absorption, Vibrio cholerae infection 💬[1] 144 💬
54RUFINAMIDE[1] Rufinamide[1] Rufinamide 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 144 💬
55Rufinamide (E2080)[1] Rufinamide[1] Rufinamide 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 144 💬
56Rufinamide oral suspension[1] Rufinamide[1] Rufinamide 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 144 💬
57Sodio valproato----[1] 144 💬
58SOTICLESTAT[1] Soticlestat[1] Soticlestat 💬 [1] CYP46A1 💬 [1] Primary bile acid biosynthesis 💬[2] 140, 144 💬
59SoticlestatProduct Code: TAK-935Pharmaceutical Form: Film-coated tabletINN or Proposed INN: SOTICLESTATCAS Number: 1429505-03-2Current Sponsor code: TAK-935Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 100-Product Name: soticlestatProduct Code: TAK-935Pharmaceutical Form: Film-coated tabletINN or Proposed INN: SOTICLESTATCAS Number: 1429505-03-2Current Sponsor code: TAK-935Concentration unit: mg milligram(s)Concentration type: equalConcentration number: 20-----[2] 140, 144 💬
60TAK-935----[2] 140, 144 💬
61Topimarate----[1] 144 💬
62Topimarato----[1] 144 💬
63TOPIRAMATE[1] Topiramate[1] Topiramate 💬 [37] CA2,
CA4,
CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S,
GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ,
GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[55] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Arrhythmogenic right ventricular cardiomyopathy, Bile secretion, Cadherin signaling, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cocaine addiction, Collecting duct acid secretion, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Huntington disease, Hypertrophic cardiomyopathy, IgSF CAM signaling, Insulin secretion, Long-term depression, Long-term potentiation, MAPK signaling pathway, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Nitrogen metabolism, Oxytocin signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Prion disease, Proximal tubule bicarbonate reclamation, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Tight junction, Transcriptional misregulation in cancer, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[6] 6, 97, 140, 144, 156, 193 💬
64Turmeric[1] Turmeric---[4] 140, 144, 158, 299 💬
65YKP509----[1] 144 💬
66ZX008----[2] 140, 144 💬
67ZX008 (Fenfluramine Hydrochloride)[1] Fenfluramine[2] Fenfluramine hydrochloride ,
Fenfluramine 💬 		[5] HTR1D,
HTR2A,
HTR2C,
SIGMAR1,
SLC6A4 💬 		[11] Amyotrophic lateral sclerosis, Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways of neurodegeneration - multiple diseases, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬[2] 140, 144 💬
68ZX008 0.2 or 0.8 mg/kg/day----[1] 144 💬
69ZX008 0.2 to 0.8 mg/kg/day----[2] 140, 144 💬