Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Aliskiren[1] Aliskiren[2] Aliskiren ,
Aliskiren fumarate 💬 		[1] REN 💬 [3] Diabetic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[4] 66, 167, 222, 223 💬
2Aprovel----[1] 167 💬
3ATENOLOL[1] Atenolol[1] Atenolol 💬 [1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
4Atenolol or Propranolol[2] Atenolol,
Propranolol		[3] Atenolol ,
Propranolol hydrochloride ,
Propranolol 💬 		[3] ADRB1,
ADRB2,
ADRB3 💬 		[14] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
5Blokium 50----[1] 167 💬
6BLOKIUM 50 mg comprimidos----[1] 167 💬
7Blood pressure and heart rate measurement----[1] 167 💬
8Blood samples----[14] 13, 41, 46, 49, 51, 61, 63, 96, 97, 160, 167, 227, 240, 271 💬
9Carotid to femoral PWW measurement----[1] 167 💬
10Collection of samples of blood and urine----[1] 167 💬
11Coozar----[1] 167 💬
12Coversyl----[2] 19, 167 💬
13Coversyl (perindopril)[1] Perindopril[3] Perindopril erbumine ,
Perindopril ,
Perindopril arginine 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[1] 167 💬
14Cozaar----[1] 167 💬
15Cozaar 50----[1] 167 💬
16COZAAR INICIO 12,5 mg comprimidos recubiertos con pelicula----[1] 167 💬
17Doxycycline[1] Doxycycline[5] Doxycycline ,
Doxycycline hyclate ,
Doxycycline calcium ,
Doxycycline ,
Doxycycline hydrochloride 💬 		--[17] 13, 23, 28, 34, 46, 84, 85, 89, 96, 97, 158, 161, 162, 167, 227, 280, 299 💬
18Doxycycline 100-200mg capsules daily for 6 months[1] Doxycycline[5] Doxycycline ,
Doxycycline hyclate ,
Doxycycline calcium ,
Doxycycline ,
Doxycycline hydrochloride 💬 		--[1] 167 💬
19Doxycycline Hyclate Ph.Eur[1] Doxycycline[5] Doxycycline ,
Doxycycline hyclate ,
Doxycycline calcium ,
Doxycycline ,
Doxycycline hydrochloride 💬 		--[1] 167 💬
20Genetic: Bloodsampling----[1] 167 💬
21Genetic: Saliva collection (screening of all participants)----[1] 167 💬
22Gold[1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
23Irbesartan[1] Irbesartan[1] Irbesartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[6] 57, 66, 167, 168, 222, 223 💬
24Irbesartan 150-300mg capsules daily for 6 months[1] Irbesartan[1] Irbesartan 💬 [1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 167 💬
25Laser doppler vibrometry (LDV), heart(cordium) carotid pulse wave velocity (ccPWV)----[1] 167 💬
26LOBIVON*28CPR 5MG----[1] 167 💬
27LORTAAN*28CPR RIV DIV 50MG----[1] 167 💬
28Losartan[1] Losartan[2] Losartan potassium ,
Losartan 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬
29Losartan and Atenolol or Propranolol[3] Atenolol,
Losartan,
Propranolol		[5] Atenolol ,
Losartan potassium ,
Propranolol hydrochloride ,
Losartan ,
Propranolol 💬 		[4] ADRB1,
ADRB2,
ADRB3,
AGTR1 💬 		[25] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
30Losartan and nebivolol[2] Losartan,
Nebivolol		[4] Losartan potassium ,
Nebivolol ,
Nebivolol hydrochloride ,
Losartan 💬 		[2] ADRB1,
AGTR1 💬 		[24] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Renin-angiotensin system, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
31LOSARTAN POTASSIUM[2] Losartan,
Potassium		[3] Losartan potassium ,
Losartan ,
Potassium 💬 		[1] AGTR1 💬 [17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[5] 36, 98, 167, 179, 215 💬
32Nebivolol[1] Nebivolol[2] Nebivolol ,
Nebivolol hydrochloride 💬 		[1] ADRB1 💬 [13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[4] 17, 85, 113, 167 💬
33Other: Blood draw----[17] 2, 6, 11, 13, 18, 39, 46, 57, 77, 84, 85, 86, 88, 96, 97, 167, 299 💬
34Perindopril[1] Perindopril[3] Perindopril erbumine ,
Perindopril ,
Perindopril arginine 💬 		[1] ACE 💬 [6] Chagas disease, Coronavirus disease, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[5] 57, 58, 113, 167, 222 💬
35Potassium[1] Potassium[1] Potassium 💬 --[17] 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬
36Propranolol[1] Propranolol[2] Propranolol hydrochloride ,
Propranolol 💬 		[3] ADRB1,
ADRB2,
ADRB3 💬 		[14] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 158, 167, 215, 216, 227, 278 💬
37Questionnaire completion----[1] 167 💬
38Valsacor----[2] 167, 168 💬
39Valsartanum 40 mg / Placebo 1----[2] 167, 168 💬
40Valsartanum 80 mg / Placebo 2----[2] 167, 168 💬
41Valzek----[2] 167, 168 💬
42Verapamil[1] Verapamil[2] Verapamil hydrochloride ,
Verapamil 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[5] 57, 58, 96, 140, 167 💬
43Verapamil SR[1] Verapamil[2] Verapamil hydrochloride ,
Verapamil 💬 		[4] CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		[37] Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 167 💬
44Vibrox----[1] 167 💬
45Vibrox 100mg Capsules----[1] 167 💬