Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
111C-flumazenil----[1] 206 💬
218F-FTC-146----[1] 206 💬
35-hydroxytryptophan / vitamin B6----[1] 206 💬
4Acamprosate[1] Acamprosate[2] Acamprosate calcium ,
Acamprosate 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[2] 6, 206 💬
5Acidum ascorbicum D6[1] Ascorbic acid[1] Ascorbic acid 💬 --[1] 206 💬
6AF056----[1] 206 💬
7AFQ056----[3] 6, 8, 206 💬
8Alpha-tocopherol[1] Vitamin E[1] Vitamin E 💬 --[2] 49, 206 💬
9Arbaclofen[1] Arbaclofen[1] Arbaclofen 💬 [2] GABBR,
GABBR 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[2] 13, 206 💬
10Aripiprazole[1] Aripiprazole[1] Aripiprazole 💬 [4] DRD2,
DRD3,
HTR1,
HTR2 💬 		[14] Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬[2] 6, 206 💬
11Ascorbic acid[1] Ascorbic acid[1] Ascorbic acid 💬 --[4] 10, 97, 206, 298 💬
12AZD7325----[1] 206 💬
13Baclofen[1] Baclofen[1] Baclofen 💬 [2] GABBR,
GABBR 💬 		[8] Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬[7] 2, 10, 13, 18, 65, 149, 206 💬
14Biological samples----[2] 13, 206 💬
15Blood sample----[28] 2, 3, 8, 13, 34, 46, 49, 51, 53, 61, 65, 66, 67, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 280, 288, 294, 299 💬
16BPN14770----[1] 206 💬
17BPN14770/ zatolmilast----[1] 206 💬
18Cannabidiol[1] Cannabidiol[1] Cannabidiol 💬 [2] CNR1,
CNR2 💬 		[4] Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬[18] 6, 8, 13, 19, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 271 💬
19CBD oral solution----[1] 206 💬
20CCD 1042, MD 9150000, mepalon 1042, SPT316----[2] 152, 206 💬
21Cognitive training----[1] 206 💬
22CTH120----[1] 206 💬
23CX516[1] CX516---[1] 206 💬
24Donepezil[1] Donepezil[2] Donepezil hydrochloride ,
Donepezil 💬 		[1] ACHE 💬 [3] Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬[8] 5, 6, 13, 46, 124, 127, 156, 206 💬
25Egcg[1] Epigallocatechin gallate---[6] 6, 8, 13, 28, 85, 206 💬
26Egcg fontup[1] Epigallocatechin gallate---[1] 206 💬
27Ergoloid mesylate[1] Ergoloid mesylate[1] Ergoloid mesylates 💬 [6] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C 💬 		[9] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬[1] 206 💬
28Flumazenil[1] Flumazenil[1] Flumazenil 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206 💬
29Gaboxadol[1] Gaboxadol[1] Gaboxadol 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 201, 206 💬
30Ganaxolone[1] Ganaxolone[1] Ganaxolone 💬 [16] GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		[8] GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[4] 145, 152, 158, 206 💬
31Language intervention----[1] 206 💬
32Lovastatin[1] Lovastatin[1] Lovastatin 💬 [1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[11] 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
33Lovastatin, then minocycline/lovastatin[2] Lovastatin,
Minocycline		[3] Lovastatin ,
Minocycline hydrochloride ,
Minocycline 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 206 💬
34Mavoglurant[1] Mavoglurant---[2] 6, 206 💬
35Memantine[1] Memantine[2] Memantine hydrochloride ,
Memantine 💬 		[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬[8] 2, 6, 8, 13, 49, 127, 205, 206 💬
36Metformin[1] Metformin[2] Metformin hydrochloride ,
Metformin 💬 		[2] PRKAA,
PRKAA 💬 		[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬[23] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 84, 86, 97, 113, 127, 206, 218, 225, 265, 285, 298 💬
37Methylphenidate oral solution[1] Methylphenidate[2] Methylphenidate hydrochloride ,
Methylphenidate 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[1] 206 💬
38Methylphenidate, fluoxetin, risperidone[1] Methylphenidate[2] Methylphenidate hydrochloride ,
Methylphenidate 💬 		[2] SLC6A2,
SLC6A3 💬 		[8] Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬[2] 179, 206 💬
39MG01CI extended-release tablet----[1] 206 💬
40MGLU5 antagonist----[1] 206 💬
41Minocycline[1] Minocycline[2] Minocycline hydrochloride ,
Minocycline 💬 		--[14] 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
42Minocycline hydrochloride[1] Minocycline[2] Minocycline hydrochloride ,
Minocycline 💬 		--[4] 13, 201, 206, 299 💬
43Minocycline, then minocycline/lovastatin[2] Lovastatin,
Minocycline		[3] Lovastatin ,
Minocycline hydrochloride ,
Minocycline 💬 		[1] HMGCR 💬 [3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬[1] 206 💬
44NNZ-2566----[2] 156, 206 💬
45NON invasive prenatal diagnosis----[3] 8, 113, 206 💬
46NPL-2009----[1] 206 💬
47OV101----[2] 201, 206 💬
48Oxytocin 24IU[1] Oxytocin[1] Oxytocin 💬 [1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 206 💬
49Oxytocin 48IU[1] Oxytocin[1] Oxytocin 💬 [1] OXTR 💬 [5] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬[1] 206 💬
50Probiotics----[6] 6, 94, 96, 97, 206, 291 💬
51Psilocybin, 1.5 MG[1] Psilocybin[1] Psilocybin 💬 [1] HTR2 💬 [6] Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬[1] 206 💬
52Riluzole[1] Riluzole[1] Riluzole 💬 [14] GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		[24] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬[8] 2, 3, 5, 8, 13, 17, 203, 206 💬
53RO 491-7523/F18----[1] 206 💬
54RO 491-7523/F19----[1] 206 💬
55RO4917523----[1] 206 💬
56RO4917523 0.5 MG----[1] 206 💬
57RO4917523 1.5 MG----[1] 206 💬
58Roflumilast[1] Roflumilast[1] Roflumilast 💬 [4] PDE4,
PDE4,
PDE4,
PDE4 💬 		[4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[4] 84, 97, 206, 299 💬
59Sertraline[1] Sertraline[2] Sertraline hydrochloride ,
Sertraline 💬 		[1] SLC6A4 💬 [3] Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬[3] 6, 158, 206 💬
60SPG601[1] SPG601---[1] 206 💬
61STX107----[1] 206 💬
62STX209----[1] 206 💬
63Sugar pill----[9] 5, 6, 49, 67, 70, 86, 90, 206, 210 💬
64Sulindac (HLX-0201), dose strength 1[1] Sulindac[1] Sulindac 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206 💬
65Sulindac (HLX-0201), dose strength 2[1] Sulindac[1] Sulindac 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 206 💬
66Tocopheryl acetate[1] alpha-Tocopherol acetate[1] Tocopherol acetate 💬 --[1] 206 💬
67Vitamin C[1] Ascorbic acid[1] Ascorbic acid 💬 --[6] 10, 192, 206, 210, 211, 212 💬
68Vitamin E[1] Vitamin E[1] Vitamin E 💬 --[5] 2, 19, 20, 90, 206 💬
69Water[1] Water[1] Water 💬 --[25] 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬
70Zatolmilast[1] Zatolmilast[1] Zatolmilast 💬 [1] PDE4 💬 [4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 206 💬
71Zatolmilast/ BPN14770[1] Zatolmilast[1] Zatolmilast 💬 [1] PDE4 💬 [4] Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[1] 206 💬
72ZYN002----[2] 203, 206 💬
73ZYN002 - cannabidiol transdermal GEL----[1] 206 💬
74ZYN002 - CBD transdermal GEL----[1] 206 💬
75ZYN002 - transdermal GEL----[1] 206 💬