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KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Alpha-tocopherol

[1] Tocopherol

[1] Tocopherol 💬

[2] 49, 215 💬

Blood draw

[16] 3, 6, 13, 19, 46, 48, 49, 51, 58, 65, 67, 193, 215, 231, 298, 299 💬

Disease ID	Name
3	Spinal muscular atrophy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
51	Scleroderma
58	Hypertrophic cardiomyopathy
65	Primary immunodeficiency
67	Polycystic kidney disease
193	Prader-Willi syndrome
215	Tetralogy of Fallot
231	Alpha-1-antitrypsin deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis

Calcium

[1] Calcium

[39] 2, 3, 6, 13, 15, 19, 46, 48, 49, 51, 53, 56, 62, 67, 68, 71, 74, 75, 79, 84, 90, 93, 94, 95, 96, 97, 156, 186, 214, 215, 222, 224, 235, 256, 265, 271, 274, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
19	Lysosomal storage disease
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
56	Behcet disease
62	Paroxysmal nocturnal hemoglobinuria
67	Polycystic kidney disease
68	Ossification of the ligamentum flavum
71	Idiopathic osteonecrosis of the femoral head
74	Prolactin secreting pituitary adenoma
75	Cushing disease
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
90	Retinitis pigmentosa
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
156	Rett syndrome
186	Rothmund-Thomson syndrome
214	Pulmonary atresia with ventricular septum defect
215	Tetralogy of Fallot
222	Primary nephrotic syndrome
224	Purpura nephritis
235	Hypoparathyroidism
256	Muscle glycogenosis
265	Lipodystrophy
271	Ankylosing spondylitis
274	Osteogenesis Imperfecta
298	Hereditary pancreatitis
299	Cystic fibrosis

Calcium gluconate

[2] Calcium,
Calcium gluconate

[1] Calcium gluconate 💬

[3] 214, 215, 235 💬

Cardiac Magnetic Resonance Imaging (CMRI)

[1] 215 💬

Cardiac MRI (CMR)

[2] 215, 216 💬

Cellvizio 100 Series System with Confocal Miniprobes

[1] 215 💬

Central venous line placement

[1] 215 💬

Chest X-ray

[1] 215 💬

Cold Cadioplegia

[1] 215 💬

Dapagliflozin

[1] Dapagliflozin

[1] Dapagliflozin 💬

[16] 6, 19, 28, 40, 41, 49, 57, 66, 67, 86, 88, 97, 210, 215, 218, 222 💬

Disease ID	Name
6	Parkinson disease
19	Lysosomal storage disease
28	Systemic amyloidosis
40	Takayasu arteritis
41	Giant cell arteritis
49	Systemic lupus erythematosus
57	Idiopathic dilated cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
97	Ulcerative colitis
210	Single Ventricle
215	Tetralogy of Fallot
218	Alport syndrome
222	Primary nephrotic syndrome

DEXMEDETOMIDINE

[1] Dexmedetomidine

[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬

Name	Other Names
Dexmedetomidine	Dexdor Precedex
Dexmedetomidine hydrochloride	Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE

[3] ADRA2A,
ADRA2B,
ADRA2C 💬

[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[15] 2, 4, 6, 21, 22, 34, 46, 70, 107, 113, 171, 212, 215, 226, 280 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
4	Primary lateral sclerosis
6	Parkinson disease
21	Mitochondrial disease
22	Moyamoya disease
34	Neurofibromatosis
46	Malignant rheumatoid arthritis
70	Spinal stenosis
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
171	Wilson disease
212	Tricuspid atresia
215	Tetralogy of Fallot
226	Interstitial cystitis with Hunners ulcer
280	Huge arteriovenous malformation with cervicofacial or limb lesion

Dexmedetomidine Hcl 100 Mcg/mL Inj

[1] Dexmedetomidine

[2] Dexmedetomidine ,
Dexmedetomidine hydrochloride 💬

Name	Other Names
Dexmedetomidine	Dexdor Precedex
Dexmedetomidine hydrochloride	Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE

[3] ADRA2A,
ADRA2B,
ADRA2C 💬

[4] Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[1] 215 💬

Dobutamin

[1] 215 💬

Dobutamine

[1] Dobutamine

[3] Dobutamine hydrochloride ,
Dobutamine ,
Dobutamine tartrate 💬

[1] ADRB1 💬

[13] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[5] 28, 57, 58, 86, 215 💬

Echocardiogram

[3] 19, 215, 216 💬

Electrocardiogram

[1] 215 💬

Eplerenone

[1] Eplerenone

[1] Eplerenone 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[5] 57, 75, 113, 210, 215 💬

Fentanyl

[1] Fentanyl

[3] Fentanyl ,
Fentanyl citrate ,
Fentanyl hydrochloride 💬

[1] OPRM1 💬

[5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬

[6] 46, 70, 97, 215, 231, 298 💬

Fentanyl (High Dose)

[1] Fentanyl

[3] Fentanyl ,
Fentanyl citrate ,
Fentanyl hydrochloride 💬

[1] OPRM1 💬

[5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬

[1] 215 💬

Fentanyl (Low Dose)

[1] Fentanyl

[3] Fentanyl ,
Fentanyl citrate ,
Fentanyl hydrochloride 💬

[1] OPRM1 💬

[5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬

[1] 215 💬

Fentanyl (Low Dose) + Dexmedetomidine

[2] Dexmedetomidine,
Fentanyl

[5] Fentanyl ,
Dexmedetomidine ,
Dexmedetomidine hydrochloride ,
Fentanyl citrate ,
Fentanyl hydrochloride 💬

Name	Other Names
Fentanyl	Duragesic Subsys
Dexmedetomidine	Dexdor Precedex
Dexmedetomidine hydrochloride	Igalmi Precedex DEXMEDETOMIDINE DEXMEDETOMIDINE HCL DEXMEDETOMIDINE HYDROCHLORIDE IN 0.9% SODIUM CHLORIDE DEXMEDETOMIDINE HYDROCHLORIDE IN SODIUM CHLORIDE
Fentanyl citrate	Abstral Fentora Lazanda Oralet
Fentanyl hydrochloride	Ionsys

[4] ADRA2A,
ADRA2B,
ADRA2C,
OPRM1 💬

[6] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬

[1] 215 💬

Fluid administration

[1] 215 💬

Fluorescite

[1] 215 💬

Gold

[1] Gold

[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
5	Progressive supranuclear palsy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
17	Multiple system atrophy
19	Lysosomal storage disease
21	Mitochondrial disease
22	Moyamoya disease
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
53	Sjogren syndrome
54	Adult still disease
56	Behcet disease
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
68	Ossification of the ligamentum flavum
71	Idiopathic osteonecrosis of the femoral head
75	Cushing disease
76	Pituitary gonadotropin secretion hyperthyroidism
77	Growth hormone secreting pituitary adenoma
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
91	Budd-Chiari syndrome
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
107	Juvenile idiopathic arthritis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
137	Focal cortical dysplasia
158	Tuberous sclerosis
162	Pemphigoid
167	Marfan syndrome
171	Wilson disease
193	Prader-Willi syndrome
206	Fragile X syndrome
215	Tetralogy of Fallot
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
226	Interstitial cystitis with Hunners ulcer
227	Osler disease
228	Bronchiolitis obliterans
230	Alveolar hypoventilation syndrome
235	Hypoparathyroidism
271	Ankylosing spondylitis
291	Hirschsprung disease, entire colon type
294	Congenital diaphragmatic hernia
296	Biliary atresia
298	Hereditary pancreatitis
299	Cystic fibrosis
310	Congenital anomalies syndrome
318	Citrin deficiency
331	Idiopathic multicentric castleman disease
340	Primary ciliary dyskinesia

HTK cardioplegia

[1] 215 💬

KETAMINE

[1] Ketamine

[2] Ketamine hydrochloride ,
Ketamine 💬

[5] GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬

Name	Full Name
GRIN1	glutamate receptor ionotropic, NMDA 1 isoform GluN1-1a precursor
GRIN2A	glutamate receptor ionotropic, NMDA 2A isoform 1 precursor
GRIN2B	glutamate receptor ionotropic, NMDA 2B isoform a precursor
GRIN2C	glutamate receptor ionotropic, NMDA 2C isoform 1 precursor
GRIN2D	glutamate receptor ionotropic, NMDA 2D precursor

[21] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬

[6] 6, 13, 70, 113, 156, 215 💬

Losartan

[1] Losartan

[2] Losartan potassium ,
Losartan 💬

[1] AGTR1 💬

[17] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬

[20] 17, 19, 36, 46, 57, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 223, 299 💬

Disease ID	Name
17	Multiple system atrophy
19	Lysosomal storage disease
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
113	Muscular dystrophy
164	Oculocutaneous albinism
167	Marfan syndrome
179	Williams syndrome
215	Tetralogy of Fallot
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
299	Cystic fibrosis

LOSARTAN POTASSIUM

[2] Losartan,
Potassium

[3] Losartan potassium ,
Losartan ,
Potassium 💬

[1] AGTR1 💬

[5] 36, 98, 167, 179, 215 💬

Other: blood cardioplegia

[1] 215 💬

Other: del nido cardioplegia

[1] 215 💬

Other: dobutamine

[1] Dobutamine

[3] Dobutamine hydrochloride ,
Dobutamine ,
Dobutamine tartrate 💬

[1] ADRB1 💬

[1] 215 💬

Other: N-thymidine

[1] Thymidine

[1] Doxribtimine 💬

[1] TK2 💬

[2] Drug metabolism - other enzymes, Pyrimidine metabolism 💬

[2] 215, 216 💬

Other: N15-thymidine

[1] Thymidine

[1] Doxribtimine 💬

[1] TK2 💬

[2] Drug metabolism - other enzymes, Pyrimidine metabolism 💬

[1] 215 💬

Other: Specimen Collection

[2] 215, 216 💬

Other: Transthoracic echocardiography at rest, during PLR, HG and CPX (including blood gas analysis in both groups). Additionally Fallot patients will undergo routine blood testings.

[1] 215 💬

Other: Urine Collection

[2] 215, 216 💬

Physical Exam

[2] 215, 216 💬

Potassium

[1] Potassium

[1] Potassium 💬

[17] 36, 46, 57, 58, 66, 67, 88, 93, 94, 97, 98, 115, 167, 179, 215, 223, 235 💬

Disease ID	Name
36	Epidermolysis bullosa
46	Malignant rheumatoid arthritis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
66	IgA nephropathy
67	Polycystic kidney disease
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
115	Hereditary periodic paralysis
167	Marfan syndrome
179	Williams syndrome
215	Tetralogy of Fallot
223	Primary membranoproliferative glomerulonephritis
235	Hypoparathyroidism

Pregnancy test

[2] 50, 215 💬

Propranolol

[1] Propranolol

[2] Propranolol hydrochloride ,
Propranolol 💬

[3] ADRB1,
ADRB2,
ADRB3 💬

[14] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, cAMP signaling pathway, cGMP-PKG signaling pathway 💬

[7] 6, 158, 167, 215, 216, 227, 278 💬

Propranolol Hydrochloride

[1] Propranolol

[2] Propranolol hydrochloride ,
Propranolol 💬

[3] ADRB1,
ADRB2,
ADRB3 💬

[2] 215, 216 💬

Recombinant human brain natriuretic peptide (rhBNP)

[1] 215 💬

SGLT2 inhibitor (Dapagliflozin 10mg)

[1] Dapagliflozin

[1] Dapagliflozin 💬

[1] 215 💬

SGLT2 inhibitors

[3] 208, 210, 215 💬

Sodium chloride

[1] Sodium chloride

[1] Sodium chloride 💬

[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
22	Moyamoya disease
34	Neurofibromatosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
65	Primary immunodeficiency
67	Polycystic kidney disease
70	Spinal stenosis
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
168	Ehlers-Danlos syndrome
193	Prader-Willi syndrome
214	Pulmonary atresia with ventricular septum defect
215	Tetralogy of Fallot
226	Interstitial cystitis with Hunners ulcer
227	Osler disease
228	Bronchiolitis obliterans
271	Ankylosing spondylitis
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis

Sodium citrate

[1] Sodium citrate

[1] Sodium citrate 💬

[4] 67, 214, 215, 235 💬

Sterile Water for Injection

[1] Water

[1] Water 💬

[1] 215 💬

SULFUR HEXAFLUORIDE

[1] Sulfur hexafluoride

[1] Sulfur hexafluoride 💬

[3] 96, 97, 215 💬

Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Injection Powder for Suspension [LUMASON]

[1] Sulfur hexafluoride

[1] Sulfur hexafluoride 💬

[1] 215 💬

Thymidine

[1] Thymidine

[1] Doxribtimine 💬

[1] TK2 💬

[2] Drug metabolism - other enzymes, Pyrimidine metabolism 💬

[2] 215, 216 💬

Tocopherol

[1] Tocopherol

[1] Tocopherol 💬

[7] 13, 49, 71, 206, 215, 257, 298 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
49	Systemic lupus erythematosus
71	Idiopathic osteonecrosis of the femoral head
206	Fragile X syndrome
215	Tetralogy of Fallot
257	Hepatic glycogenosis
298	Hereditary pancreatitis

Tranexamic acid

[1] Tranexamic acid

[1] Tranexamic acid 💬

[1] PLG 💬

[4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection 💬

[7] 46, 65, 70, 215, 227, 274, 299 💬

Water

[1] Water

[1] Water 💬

[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
5	Progressive supranuclear palsy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
17	Multiple system atrophy
19	Lysosomal storage disease
22	Moyamoya disease
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
56	Behcet disease
57	Idiopathic dilated cardiomyopathy
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
70	Spinal stenosis
72	Pituitary ADH secretion disorder
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
96	Crohn disease
97	Ulcerative colitis
206	Fragile X syndrome
215	Tetralogy of Fallot
225	Congenital nephrogenic diabetes insipidus
226	Interstitial cystitis with Hunners ulcer
230	Alveolar hypoventilation syndrome
240	Phenylketonuria
274	Osteogenesis Imperfecta
278	Huge lymphatic malformation with cervicofacial lesion
299	Cystic fibrosis