Drug Description in Trials / DrugBank / KEGG DRUG

  

Search results

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1(4S)-4-[4-cyano-2-(methylsulfonyl)phenyl]-3,6-dimethyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydropyrimidine-5-carbonitrile----[1] 231 💬
220-valent pneumococcal conjugate vaccine----[1] 231 💬
34-PBA----[1] 231 💬
4[ARO-AAT]----[1] 231 💬
5AAV8hAAT(AVL)----[1] 231 💬
6Abdominal ultrasound----[2] 19, 231 💬
7Acetaminophen[1] Acetaminophen[1] Acetaminophen 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[19] 11, 13, 19, 34, 35, 46, 49, 51, 63, 70, 77, 86, 96, 222, 231, 256, 271, 300, 337 💬
8ADS-001----[1] 231 💬
9Aerosolized human Alpha-1 Antitrypsin----[1] 231 💬
10AIR-001 MD dose level 1----[1] 231 💬
11AIR-001 MD dose level 2----[1] 231 💬
12AIR-001 MD dose level 3----[1] 231 💬
13AIR-001 MD dose level 4----[1] 231 💬
14AIR-001 MD dose level 5----[1] 231 💬
15AIR-001 MD dose level 6----[1] 231 💬
16AIR-001 SAD dose level 1----[1] 231 💬
17AIR-001 SAD dose level 2----[1] 231 💬
18AIR-001 SAD dose level 3----[1] 231 💬
19AIR-001 SAD dose level 4----[1] 231 💬
20Albumin (Human) 20%, United States Pharmacopeia (USP)----[1] 231 💬
21Albuterol[1] Albuterol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[9] 12, 13, 86, 89, 113, 231, 256, 299, 340 💬
22Albuterol inhaler.[1] Albuterol[2] Albuterol sulfate ,
Albuterol 💬 		[1] ADRB2 💬 [11] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 231, 299 💬
23ALN-61444----[1] 231 💬
24ALN-77412----[1] 231 💬
25ALN-AAT----[1] 231 💬
26ALN-AAT02----[1] 231 💬
27Alpha 1-Antitrypsin----[2] 231, 298 💬
28Alpha 1-proteinase inhibitor (human)----[1] 231 💬
29Alpha-1 15%----[1] 231 💬
30Alpha-1 Antitrypsin (AAT)----[1] 231 💬
31Alpha-1 Antitrypsin (human)----[1] 231 💬
32Alpha-1 MP----[1] 231 💬
33Alpha-1 proteinase inhibitor (human)----[1] 231 💬
34ALPHA-1-ANTITRYPSIN----[1] 231 💬
35Alpha1-Proteinase Inhibitor----[1] 231 💬
36Alpha1-Proteinase Inhibitor (Human)----[2] 231, 299 💬
37ALVELESTAT[1] Alvelestat---[1] 231 💬
38Alvelestat (MPH966)[1] Alvelestat---[1] 231 💬
39Alvelestat oral tablet - dose 1[1] Alvelestat---[1] 231 💬
40Alvelestat oral tablet - dose 2[1] Alvelestat---[1] 231 💬
41Alvelestat tosylate[1] Alvelestat---[1] 231 💬
42API-AAT----[1] 231 💬
43API-AAT, AD00370, ARC-AAT, API drug Substance----[1] 231 💬
44ARC-AAT----[1] 231 💬
45ARC-AAT Injection----[1] 231 💬
46ARO-AAT[1] Fazirsiran---[1] 231 💬
47ARO-AAT Injection----[1] 231 💬
48Aspirin[1] Acetylsalicylic acid[1] Aspirin 💬 [2] PTGS1,
PTGS2 💬 		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[10] 22, 34, 48, 49, 51, 63, 86, 158, 210, 231 💬
49BEAM-302----[1] 231 💬
50Belcesiran[1] Belcesiran---[1] 231 💬
51Biological NTLA-3001----[1] 231 💬
52Blood draw----[16] 3, 6, 13, 19, 46, 48, 49, 51, 58, 65, 67, 193, 215, 231, 298, 299 💬
53Blood draw.----[2] 231, 299 💬
54BMN 349----[1] 231 💬
55Carbamazepine[1] Carbamazepine[1] Carbamazepine 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[6] 6, 13, 137, 145, 158, 231 💬
56Diagnostic Test: Blood sampling----[8] 49, 51, 65, 74, 97, 127, 231, 299 💬
57Dose of 60 mg/kg alpha1-proteinase inhibitor----[1] 231 💬
58Dose of 60 mg/kg Fraction IV-1 Alpha1-Proteinase Inhibitor----[1] 231 💬
59Drug-Carbamazepine (Tegretol XR)[1] Carbamazepine[1] Carbamazepine 💬 [6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[1] 231 💬
60Fazirsiran[1] Fazirsiran---[1] 231 💬
61Fazirsiran (TAK-999, also referred to as ARO-AAT) Injection[1] Fazirsiran---[1] 231 💬
62Fazirsiran (TAK-999, ARO-AAT) Injection[1] Fazirsiran---[1] 231 💬
63Fazisiran Injection----[1] 231 💬
64Fentanyl[1] Fentanyl[3] Fentanyl ,
Fentanyl citrate ,
Fentanyl hydrochloride 💬 		[1] OPRM1 💬 [5] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬[6] 46, 70, 97, 215, 231, 298 💬
65Genetic: ADVM-043----[1] 231 💬
66Genetic: genetic sequencing----[2] 40, 231 💬
67Genetic: rAAV2-CB-hAAT Gene Vector----[1] 231 💬
68Glassia----[1] 231 💬
69History and physical----[1] 231 💬
70History and physical exam.----[2] 231, 299 💬
71Hyaluronic acid[1] Hyaluronic acid[2] Hyaluronate sodium ,
Hyaluronic acid 💬 		--[5] 46, 53, 70, 226, 231 💬
72Hyaluronic Acid Inhalation Solution[1] Hyaluronic acid[2] Hyaluronate sodium ,
Hyaluronic acid 💬 		--[1] 231 💬
73INBRX-101[1] INBRX-101---[1] 231 💬
74INBRX-101/rhAAT-Fc[1] INBRX-101---[1] 231 💬
75Intravenous catheter----[1] 231 💬
76Kamada -AAT for Inhalation or inhaled AAT (AAT)----[1] 231 💬
77Kamada -AAT for Inhalation or inhaled AAT (AAT)Pharmaceutical Form: Nebuliser solutionINN or Proposed INN: Alpha-1 Antitrypsin (AAT)CAS Number: 9041-92-3Current Sponsor code: Kamada-AATConcentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 20-Pharmaceutical form of the placebo: Nebuliser solutionRoute of administration of the placebo: Inhalation use----[1] 231 💬
78Kamada-AAT for inhalation----[1] 231 💬
79Kamada-AAT for Inhalation, 160mg----[1] 231 💬
80Kamada-AAT for Inhalation, 80mg----[1] 231 💬
81Kamada-API----[1] 231 💬
82KB408 (Nebulization)----[1] 231 💬
83KRRO-110----[1] 231 💬
84Lidocaine[1] Lidocaine[3] Lidocaine ,
Lidocaine hydrochloride ,
Lidocaine hydrochloride monohydrate 💬 		[6] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN8A,
SCN9A 💬 		[5] Adrenergic signaling in cardiomyocytes, Cadherin signaling, Dopaminergic synapse, IgSF CAM signaling, Taste transduction 💬[14] 6, 13, 22, 34, 46, 51, 70, 86, 107, 168, 226, 231, 256, 298 💬
85Liver biopsy----[3] 171, 231, 240 💬
86Lorazepam[1] Lorazepam[1] Lorazepam 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[2] 36, 231 💬
87Midazolam[1] Midazolam[3] Midazolam ,
Midazolam hydrochloride ,
Midazolam maleate 💬 		[16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[14] 2, 3, 6, 13, 21, 46, 67, 70, 96, 97, 231, 272, 298, 299 💬
88MPH966----[2] 228, 231 💬
89None assigned----[2] 231, 299 💬
90OctaAlpha1----[1] 231 💬
91Ondansetron[1] Ondansetron[2] Ondansetron ,
Ondansetron hydrochloride hydrate 💬 		[5] HTR3A,
HTR3B,
HTR3C,
HTR3D,
HTR3E 💬 		[3] Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 97, 98, 107, 231 💬
92OsrhAAT 1 mg/kg IV----[1] 231 💬
93OsrhAAT 10 mg/kg IV----[1] 231 💬
94OsrhAAT 20 mg/kg IV----[1] 231 💬
95OsrhAAT 3 mg/kg IV----[1] 231 💬
96OsrhAAT 40 mg/kg IV----[1] 231 💬
97OsrhAAT 60 mg/kg IV----[1] 231 💬
98Other: Hyperpolarized 129Xe MRI----[2] 84, 231 💬
99Other: Liquid Alpha1-PI----[1] 231 💬
100Other: Liver questionnaire----[1] 231 💬
101Other: Sterile Normal Saline (0.9% NaCl)----[1] 231 💬
102Other: Withdrawal from alpha1 antitrypsin replacement therapy----[1] 231 💬
103Oxycodone[1] Oxycodone[3] Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		[3] OPRD1,
OPRK1,
OPRM1 💬 		[7] Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬[7] 6, 13, 46, 70, 226, 231, 298 💬
104Oxycodone/Acetaminophen[2] Acetaminophen,
Oxycodone		[4] Acetaminophen ,
Oxycodone hydrochloride ,
Oxycodone terephthalate ,
Oxycodone 💬 		[5] OPRD1,
OPRK1,
OPRM1,
PTGS1,
PTGS2 💬 		[30] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Estrogen signaling pathway, Hormone signaling, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, Morphine addiction, NF-kappa B signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, Sphingolipid signaling pathway, TNF signaling pathway, VEGF signaling pathway, cGMP-PKG signaling pathway 💬[1] 231 💬
105PHP-303----[1] 231 💬
106Prolastin----[1] 231 💬
107Prolastin-C----[2] 231, 298 💬
108Prolastin-C, 120 mg/kg----[1] 231 💬
109Prolastin-C, 60 mg/kg----[1] 231 💬
110Pulmonary function testing.----[2] 231, 299 💬
111RAAV1-CB-hAAT[1] rAAV1-CB-hAAT---[1] 231 💬
112RECOMBINANT ADENO-ASSOCIATED VIRAL VECTOR EXPRESSING THE HUMAN ALPHA-1-ANTITRYPSIN GENE----[1] 231 💬
113Retinoic Acid Receptor gamma Agonist----[1] 231 💬
114RO3300074----[1] 231 💬
115SAR447537----[1] 231 💬
116TAK-999, ARO-AAT[1] Fazirsiran---[1] 231 💬
117TSRA-196----[1] 231 💬
118VX-634----[1] 231 💬
119VX-668----[1] 231 💬
120VX-814----[1] 231 💬
121VX-864----[1] 231 💬
122VX864----[1] 231 💬
123WVE-006----[1] 231 💬
124YOLT-202----[1] 231 💬
125Zemaira----[1] 231 💬