Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1Abatacept[1] Abatacept[1] Abatacept 💬 [2] CD80,
CD86 💬 		[13] Allograft rejection, Autoimmune thyroid disease, Cell adhesion molecules, Graft-versus-host disease, Intestinal immune network for IgA production, Kaposi sarcoma-associated herpesvirus infection, Rheumatoid arthritis, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Type I diabetes mellitus, Viral myocarditis, Virion - Adenovirus 💬[26] 2, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬
2Alefacept[1] Alefacept[1] Alefacept 💬 [1] CD58 💬 [2] Cell adhesion molecules, Epstein-Barr virus infection 💬[6] 37, 60, 65, 164, 284, 285 💬
3Alemtuzumab[1] Alemtuzumab[1] Alemtuzumab 💬 --[18] 13, 15, 19, 20, 36, 43, 44, 46, 51, 60, 65, 85, 96, 107, 283, 284, 285, 326 💬
4Allogeneic bone marrow transplantation----[8] 60, 62, 65, 96, 164, 284, 285, 286 💬
5Allogeneic hematopoietic stem cell transplantation----[8] 28, 51, 60, 62, 65, 164, 284, 285 💬
6Alpha beta depletion----[2] 60, 284 💬
7ANTI-thymocyte globulin----[18] 11, 13, 14, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 164, 283, 284, 285 💬
8Antithymocyte globulin----[3] 60, 65, 284 💬
9Biospecimen collection----[18] 13, 26, 28, 34, 46, 49, 50, 51, 53, 60, 62, 65, 96, 97, 159, 284, 285, 286 💬
10Bitopertin[1] Bitopertin[1] Bitopertin 💬 [1] SLC6A5_9 💬 [2] Neuroactive ligand signaling, Synaptic vesicle cycle 💬[1] 284 💬
11Bone marrow aspiration----[8] 2, 28, 60, 62, 65, 284, 285, 286 💬
12Bone marrow biopsy----[7] 26, 28, 60, 62, 65, 284, 286 💬
13Bone marrow transplantation----[4] 51, 60, 284, 285 💬
14BPX-501 T cells----[4] 65, 284, 285, 326 💬
15Busulfan[1] Busulfan[1] Busulfan 💬 --[14] 19, 20, 28, 34, 36, 49, 51, 60, 65, 164, 274, 284, 285, 326 💬
16Busulfan, cyclophosphamide, ATG, gcsf[1] Busulfan[1] Busulfan 💬 --[2] 65, 284 💬
17Busulfan, fludarabine, ATG, TLI[1] Busulfan[1] Busulfan 💬 --[2] 65, 284 💬
18Campath, fludarabine, cyclophosphamide----[2] 65, 284 💬
19CD3/CD19 depleted leukocytes----[1] 284 💬
20CD34 stem cell selection therapy----[3] 60, 65, 284 💬
21CD45RA depleted leukocytes----[1] 284 💬
22Computed tomography----[12] 26, 28, 40, 46, 49, 60, 62, 65, 96, 284, 285, 286 💬
23Cyclophosphamide[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[44] 11, 13, 14, 16, 19, 20, 26, 28, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 56, 60, 62, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 224, 265, 274, 283, 284, 285, 288, 326, 331 💬
24Cyclophosphamide dose level 1[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[2] 65, 284 💬
25Cyclophosphamide dose level 2[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[2] 65, 284 💬
26Cyclophosphamide dose level 3[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[2] 65, 284 💬
27Cyclophosphamide dose level 4[1] Cyclophosphamide[2] Cyclophosphamide ,
Cyclophosphamide 💬 		--[2] 65, 284 💬
28Cyclosporine[1] Cyclosporine[1] Cyclosporine 💬 [5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[28] 11, 28, 40, 41, 42, 45, 46, 49, 50, 53, 56, 60, 61, 62, 63, 64, 65, 97, 107, 162, 164, 222, 226, 228, 283, 284, 285, 302 💬
29Daclizumab[1] Daclizumab[1] Daclizumab 💬 [1] IL2RA 💬 [11] Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, JAK-STAT signaling pathway, Measles, PI3K-Akt signaling pathway, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[8] 13, 56, 60, 65, 97, 107, 283, 284 💬
30Deferasirox[1] Deferasirox[1] Deferasirox 💬 --[4] 54, 254, 284, 286 💬
31Deferitazole[1] Deferitazole[1] Deferitazole 💬 --[1] 284 💬
32Deferoxamine[1] Deferoxamine[3] Deferoxamine mesylate ,
Deferoxamine ,
Deferoxamine hydrochloride 💬 		--[2] 284, 286 💬
33Desferal[1] Deferoxamine[3] Deferoxamine mesylate ,
Deferoxamine ,
Deferoxamine hydrochloride 💬 		--[2] 284, 286 💬
34DFO----[2] 284, 286 💬
35Echocardiography----[7] 28, 58, 60, 62, 65, 284, 286 💬
36Eltrombopag[1] Eltrombopag[2] Eltrombopag olamine ,
Eltrombopag choline 💬 		[1] TPOR 💬 [3] Cytokine-cytokine receptor interaction, Hormone signaling, JAK-STAT signaling pathway 💬[5] 60, 63, 65, 284, 285 💬
37Enriched hematopoetic stem cell infusion----[2] 19, 284 💬
38Exjade[1] Deferasirox[1] Deferasirox 💬 --[3] 254, 284, 286 💬
39FBS0701 capsule----[1] 284 💬
40FBS0701/SSP004184----[1] 284 💬
41Filgrastim[1] Filgrastim[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[29] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
42Fludarabine[1] Fludarabine[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[23] 11, 13, 19, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 326 💬
43Fludarabine monophosphate[1] Fludarabine[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[3] 65, 284, 326 💬
44Fludarabine phosphate[1] Fludarabine[2] Fludarabine phosphate ,
Fludarabine 💬 		[1] RRM1 💬 [4] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬[12] 28, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286 💬
45G-CSF[1] Filgrastim[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[18] 2, 6, 11, 13, 16, 22, 47, 49, 51, 60, 61, 62, 65, 85, 96, 284, 285, 331 💬
46Human placental derived stem cell----[4] 19, 20, 60, 284 💬
47Hydroxyurea[1] Hydroxyurea[1] Hydroxyurea 💬 [1] RRM2 💬 [5] Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism, p53 signaling pathway 💬[10] 3, 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
48ICL670----[3] 60, 284, 286 💬
49Iron chelating agents[1] Iron[1] Ferrous fumarate 💬 --[1] 284 💬
50L-leucine[1] Leucine[1] Leucine 💬 --[1] 284 💬
51Laboratory biomarker analysis----[22] 11, 13, 14, 26, 28, 34, 40, 49, 51, 60, 62, 65, 89, 96, 97, 205, 232, 283, 284, 285, 298, 331 💬
52Lapine T-lymphocyte immune globulin[1] Antithymocyte immunoglobulin (rabbit)[1] Anti-human thymocyte immunoglobulin, rabbit 💬 [11] CD2,
CD3D,
CD3E,
CD3G,
CD4,
CD5,
CD7,
CD8A,
CD8B,
IL2RA,
ITGAL 💬 		[31] Antigen processing and presentation, Cell adhesion molecules, Chagas disease, Cytokine-cytokine receptor interaction, Endocytosis, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Leukocyte transendothelial migration, Malaria, Measles, Natural killer cell mediated cytotoxicity, Neutrophil extracellular trap formation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pathways in cancer, Primary immunodeficiency, Rap1 signaling pathway, Regulation of actin cytoskeleton, Rheumatoid arthritis, Staphylococcus aureus infection, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Viral life cycle - HIV-1, Viral myocarditis, Viral protein interaction with cytokine and cytokine receptor, Virion - Human immunodeficiency virus, Yersinia infection 💬[4] 62, 65, 284, 286 💬
53Lenalidomide[1] Lenalidomide[1] Lenalidomide 💬 [1] TNF 💬 [66] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[8] 16, 26, 28, 34, 49, 284, 300, 331 💬
54Leucine[1] Leucine[1] Leucine 💬 --[4] 6, 283, 284, 299 💬
55Leukapheresis----[5] 49, 51, 96, 284, 285 💬
56Magnesium hydroxide[2] Magnesium,
Magnesium hydroxide		[1] Magnesium hydroxide 💬 --[1] 284 💬
57Melphalan[1] Melphalan[2] Melphalan ,
Melphalan hydrochloride 💬 		--[19] 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
58Mesenchymal stromal cells[1] Human Umbilical Cord Mesenchymal Stem Cells---[8] 36, 51, 60, 96, 97, 107, 274, 284 💬
59Methotrexate[1] Methotrexate[2] Methotrexate ,
Methotrexate sodium 💬 		[2] DHFR,
DHFR 💬 		[3] Folate biosynthesis, Folate transport and metabolism, One carbon pool by folate 💬[37] 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 54, 55, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 270, 271, 284, 285, 286, 326, 331 💬
60Methylprednisolone[1] Methylprednisolone[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[45] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
61Multigated acquisition scan----[5] 60, 62, 65, 284, 286 💬
62Mycophenolate mofetil[2] Mycophenolate mofetil,
Mycophenolic acid		[4] Mycophenolate mofetil ,
Mycophenolate mofetil hydrochloride ,
Mycophenolate sodium ,
Mycophenolic acid 💬 		[2] IMPDH,
IMPDH 💬 		[2] Drug metabolism - other enzymes, Purine metabolism 💬[32] 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
63Myeloablative preparative regimen----[3] 62, 65, 284 💬
64Peripheral blood stem cell transplantation----[12] 11, 13, 14, 28, 51, 60, 62, 65, 283, 284, 285, 286 💬
65Quality-OF-life assessment----[11] 28, 34, 36, 51, 62, 63, 65, 96, 284, 286, 298 💬
66Radiation therapy----[6] 13, 34, 60, 65, 284, 285 💬
67Reduced intensity preparative regimen----[3] 62, 65, 284 💬
68Reduced toxicity ablative regimen----[3] 62, 65, 284 💬
69Rimiducid[1] Rimiducid[1] Rimiducid 💬 [1] CASP9 💬 [34] Alzheimer disease, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Colorectal cancer, Endometrial cancer, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Huntington disease, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Measles, Non-small cell lung cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parkinson disease, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Prostate cancer, Small cell lung cancer, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, VEGF signaling pathway, Viral myocarditis, p53 signaling pathway 💬[7] 19, 49, 60, 65, 284, 285, 326 💬
70Rituximab[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[52] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
71Rivogenlecleucel[1] Rivogenlecleucel[1] Rivogenlecleucel 💬 --[6] 19, 60, 65, 284, 285, 326 💬
72Sotatercept with prednisone boost[1] Sotatercept[1] Sotatercept 💬 [1] ACVR2A 💬 [4] Cytokine-cytokine receptor interaction, Fluid shear stress and atherosclerosis, Signaling pathways regulating pluripotency of stem cells, TGF-beta signaling pathway 💬[1] 284 💬
73SSP-004184 100 MG capsule----[1] 284 💬
74SSP-004184 250 MG capsule----[1] 284 💬
75SSP-004184 375 MG capsule----[1] 284 💬
76SSP-004184 50 MG capsule----[1] 284 💬
77SSP-004184 500 MG capsule----[1] 284 💬
78SSP-004184AQ 100 MG capsule----[1] 284 💬
79SSP-004184AQ 200 MG capsule----[1] 284 💬
80SSP-004184AQ 250 MG capsule----[1] 284 💬
81SSP-004184AQ 375 MG capsule----[1] 284 💬
82SSP-004184AQ 50 MG capsule----[1] 284 💬
83Stem cell infusion----[4] 28, 60, 65, 284 💬
84Stem cell transplant----[7] 19, 20, 60, 65, 96, 164, 284 💬
85Tacrolimus[1] Tacrolimus[2] Tacrolimus ,
Tacrolimus 💬 		[5] PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[31] 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
86Thiotepa[1] Thiotepa[1] Thiotepa 💬 --[11] 13, 28, 46, 51, 60, 65, 85, 96, 107, 284, 285 💬
87Thiotepa--escalated dose[1] Thiotepa[1] Thiotepa 💬 --[4] 19, 20, 65, 284 💬
88Thiotepa--single daily dose[1] Thiotepa[1] Thiotepa 💬 --[4] 19, 20, 65, 284 💬
89Total body irradiation----[13] 19, 20, 36, 49, 51, 60, 62, 65, 96, 222, 283, 284, 285 💬
90Total lymphoid irradiation----[3] 65, 284, 326 💬
91Total-body irradiation----[9] 28, 51, 60, 62, 65, 96, 283, 284, 285 💬
92Treosulfan[1] Treosulfan[1] Treosulfan 💬 --[6] 13, 19, 62, 65, 284, 286 💬
93Trifluoperazine[1] Trifluoperazine[3] Trifluoperazine hydrochloride ,
Trifluoperazine maleate ,
Trifluoperazine 💬 		[1] DRD2 💬 [10] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 283, 284 💬
94Umbilical cord blood transplantation----[5] 60, 65, 284, 285, 326 💬
95X-RAY imaging----[5] 28, 62, 65, 284, 286 💬