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KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

436394

[1] 288 💬

BORTEZOMIB

[1] Bortezomib

[1] Bortezomib 💬

[1] PSMB5 💬

[8] Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬

[19] 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 223, 228, 256, 283, 288, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
66	IgA nephropathy
172	Hypophosphatasia
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
228	Bronchiolitis obliterans
256	Muscle glycogenosis
283	Acquired pure red cell aplasia
288	Autoimmune acquired coagulation factor deficiency
331	Idiopathic multicentric castleman disease

BT200

[1] BT200

[1] 288 💬

Coagadex(R)

[2] 28, 288 💬

Coagulation factor XIII

[1] 288 💬

Cyclophosphamide

[1] Cyclophosphamide

[2] Cyclophosphamide ,
Cyclophosphamide 💬

[50] 11, 13, 14, 16, 19, 20, 26, 28, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 62, 63, 65, 66, 84, 93, 96, 162, 164, 172, 205, 221, 222, 223, 224, 256, 265, 274, 283, 284, 285, 288, 326, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
16	Crow-Fukase syndrome
19	Lysosomal storage disease
20	Adrenoleukodystrophy
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
52	Mixed connective tissue disease
53	Sjogren syndrome
56	Behcet disease
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
84	Sarcoidosis
93	Primary biliary cholangitis
96	Crohn disease
162	Pemphigoid
164	Oculocutaneous albinism
172	Hypophosphatasia
205	Fragile X syndrome related disease
221	Anti-glomerular basement membrane disease
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
256	Muscle glycogenosis
265	Lipodystrophy
274	Osteogenesis Imperfecta
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
326	Osteopetrosis
331	Idiopathic multicentric castleman disease

Daratumumab

[1] Daratumumab

[1] Daratumumab 💬

[1] CD38 💬

[6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬

[13] 13, 16, 28, 39, 46, 48, 49, 60, 63, 222, 223, 288, 331 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
16	Crow-Fukase syndrome
28	Systemic amyloidosis
39	Toxic epidermal necrolysis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
288	Autoimmune acquired coagulation factor deficiency
331	Idiopathic multicentric castleman disease

Daratumumab and corticosteroid treatment

[1] Daratumumab

[1] Daratumumab 💬

[1] CD38 💬

[6] Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬

[1] 288 💬

Desmopressin

[1] Desmopressin

[2] Desmopressin ,
Desmopressin acetate 💬

[2] AVPR2,
F8 💬

[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬

[8] 6, 22, 64, 72, 75, 223, 225, 288 💬

Disease ID	Name
6	Parkinson disease
22	Moyamoya disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
223	Primary membranoproliferative glomerulonephritis
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

Diagnostic Test: Blood sample collection for VWF measurements in plasma

[1] 288 💬

Diagnostic Test: fibrinogen plasma concentration, coagulation factor XIII activity

[1] 288 💬

Emicizumab

[1] Emicizumab

[1] Emicizumab 💬

[2] F10,
F9 💬

[1] Complement and coagulation cascades 💬

[1] 288 💬

Emicizumab Injection

[1] Emicizumab

[1] Emicizumab 💬

[2] F10,
F9 💬

[1] Complement and coagulation cascades 💬

[1] 288 💬

[1] 288 💬

[1] 288 💬

[1] 288 💬

[1] Sodium chloride

[1] Sodium chloride 💬

[1] 288 💬

[1] 288 💬

[1] 288 💬

[1] 288 💬

[2] 64, 288 💬

Other: Blood sample collection for ECFC isolation and characterization

[1] 288 💬

Other: Genetic testing of VWF

[1] 288 💬

Physiologische Kochsalzlösung Fresenius - Infusionslösung

[1] 288 💬

Phytomenadione

[1] 288 💬

Prednisone

[1] Prednisone

[1] Prednisone 💬

[1] NR3C1 💬

[1] Neuroactive ligand-receptor interaction 💬

[58] 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 127, 145, 162, 164, 205, 222, 223, 224, 228, 251, 269, 283, 284, 285, 288, 299, 300, 303, 307, 331 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
18	Spinocerebellar degeneration
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
28	Systemic amyloidosis
35	Pemphigus
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
61	Autoimmune hemolytic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
79	Homozygous familial hypercholesterolemia
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
93	Primary biliary cholangitis
95	Autoimmune hepatitis
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
145	West syndrome
162	Pemphigoid
164	Oculocutaneous albinism
205	Fragile X syndrome related disease
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
228	Bronchiolitis obliterans
251	Urea cycle disorder
269	Pyogenic arthritis
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
299	Cystic fibrosis
300	IgG4-related disease
303	Usher syndrome
307	Canavan disease
331	Idiopathic multicentric castleman disease

Prothrombin

[1] Prothrombin

[2] 35, 288 💬

Prothrombin Complex Concentrate

[1] Prothrombin

[1] 288 💬

Recombinant Factor XIII

[1] 288 💬

Recombinant porcine coagulation factor VIII (B domain deleted)

[1] 288 💬

Recombinant porcine coagulation factor VIII (B-domain deleted)

[1] 288 💬

Rituxan

[5] 46, 60, 63, 256, 288 💬

RITUXIMAB

[1] Rituximab

[1] Rituximab 💬

[1] MS4A1 💬

[1] Hematopoietic cell lineage 💬

[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬

Disease ID	Name
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
19	Lysosomal storage disease
26	HTLV-1-associated myelopathy
34	Neurofibromatosis
35	Pemphigus
36	Epidermolysis bullosa
40	Takayasu arteritis
41	Giant cell arteritis
42	Polyarteritis nodosa
43	Microscopic polyangiitis
44	Wegener granulomatosis
45	Eosinophilic granulomatosis with Polyangiitis
46	Malignant rheumatoid arthritis
48	Primary antiphospholipid syndrome
49	Systemic lupus erythematosus
50	Dermatomyositis
51	Scleroderma
52	Mixed connective tissue disease
53	Sjogren syndrome
55	Relapsing polychondritis
56	Behcet disease
60	Aplastic anemia
61	Autoimmune hemolytic anemia
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
83	Addison disease
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
94	Primary sclerosing cholangitis
96	Crohn disease
97	Ulcerative colitis
162	Pemphigoid
172	Hypophosphatasia
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
229	Autoimmune pulmonary alveolar proteinosis
256	Muscle glycogenosis
271	Ankylosing spondylitis
274	Osteogenesis Imperfecta
283	Acquired pure red cell aplasia
284	Diamond-Blackfan anemia
285	Fanconi anemia
288	Autoimmune acquired coagulation factor deficiency
296	Biliary atresia
300	IgG4-related disease
331	Idiopathic multicentric castleman disease

RO5534262 EMICIZUMAB

[1] Emicizumab

[1] Emicizumab 💬

[2] F10,
F9 💬

[1] Complement and coagulation cascades 💬

[1] 288 💬

Saline solution

[3] 2, 34, 288 💬

Sodium chloride

[1] Sodium chloride

[1] Sodium chloride 💬

[31] 2, 6, 11, 13, 14, 22, 34, 41, 46, 50, 51, 53, 60, 65, 67, 70, 85, 96, 97, 124, 168, 193, 214, 215, 226, 227, 228, 271, 288, 298, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
14	Chronic inflammatory demyelinating polyneuropathy
22	Moyamoya disease
34	Neurofibromatosis
41	Giant cell arteritis
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
53	Sjogren syndrome
60	Aplastic anemia
65	Primary immunodeficiency
67	Polycystic kidney disease
70	Spinal stenosis
85	Idiopathic interstitial pneumonia
96	Crohn disease
97	Ulcerative colitis
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
168	Ehlers-Danlos syndrome
193	Prader-Willi syndrome
214	Pulmonary atresia with ventricular septum defect
215	Tetralogy of Fallot
226	Interstitial cystitis with Hunners ulcer
227	Osler disease
228	Bronchiolitis obliterans
271	Ankylosing spondylitis
288	Autoimmune acquired coagulation factor deficiency
298	Hereditary pancreatitis
299	Cystic fibrosis