Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY Disease ID
1[A4250]----[3] 296, 297, 338 💬
2[Maralixibat][1] Maralixibat[2] Maralixibat ,
Maralixibat chloride 💬 		[2] SLC10A1,
SLC10A2 💬 		[3] Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬[2] 296, 338 💬
3[OCA]----[1] 296 💬
4A4250----[4] 93, 296, 297, 338 💬
5Acetic acid[1] Acetic acid[1] Acetic acid, glacial 💬 --[3] 21, 97, 296 💬
6Acetylcysteine[1] Acetylcysteine[1] Acetylcysteine 💬 --[25] 2, 6, 13, 19, 20, 21, 34, 49, 51, 53, 58, 63, 85, 90, 94, 97, 111, 164, 193, 233, 296, 298, 299, 303, 337 💬
7ACIDO OBETICOLICO----[3] 93, 94, 296 💬
8Ammonia[1] Ammonia[1] Ammonia solution, strong 💬 --[6] 6, 17, 86, 88, 251, 296 💬
9Basic treatment: sulperazone + ursodeoxycholic acid + compound glycyrrhizin + methylprednisolone + vitamin AD , D , E , K + imipenem or meropenem[4] Imipenem,
Meropenem,
Methylprednisolone,
Ursodeoxycholic acid		[7] Imipenem ,
Methylprednisolone ,
Ursodiol ,
Methylprednisolone acetate ,
Meropenem ,
Imipenem ,
Meropenem 💬 		[2] NR1H4,
NR3C1 💬 		[2] Bile secretion, Neuroactive ligand-receptor interaction 💬[1] 296 💬
10BELIMUMAB[1] Belimumab[1] Belimumab 💬 [1] TNFSF13B 💬 [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis 💬[17] 11, 13, 43, 44, 46, 48, 49, 50, 51, 53, 63, 66, 95, 222, 223, 296, 300 💬
11Bezafibrate[1] Bezafibrate[1] Bezafibrate 💬 [1] PPARA 💬 [10] Adipocytokine signaling pathway, Alcoholic liver disease, Chemical carcinogenesis - receptor activation, Diabetic cardiomyopathy, Glucagon signaling pathway, Hepatitis C, Insulin resistance, Non-alcoholic fatty liver disease, PPAR signaling pathway, cAMP signaling pathway 💬[8] 20, 93, 94, 160, 296, 316, 324, 344 💬
12Bicarbonate Ringer's solution----[1] 296 💬
13Cefaclor[1] Cefaclor[2] Cefaclor ,
Cefaclor 💬 		--[1] 296 💬
14Cefoperazone[1] Cefoperazone[2] Cefoperazone sodium ,
Cefoperazone 💬 		--[1] 296 💬
15Corticosteroids----[13] 41, 46, 49, 63, 64, 97, 107, 113, 164, 222, 223, 296, 300 💬
16Cysteine[1] Cysteine[2] L-Cysteine ,
Cysteine hydrochloride 💬 		--[13] 6, 13, 19, 34, 60, 84, 85, 88, 90, 254, 296, 310, 337 💬
17Desflurane[1] Desflurane[1] Desflurane 💬 --[2] 22, 296 💬
18Desflurane anesthetics[1] Desflurane[1] Desflurane 💬 --[1] 296 💬
19Dexamethasone[1] Dexamethasone[3] Dexamethasone ,
Dexamethasone sodium phosphate ,
Dexamethasone phosphate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[29] 13, 14, 16, 19, 28, 35, 46, 53, 63, 64, 65, 70, 71, 74, 75, 81, 84, 90, 96, 97, 162, 222, 223, 235, 257, 283, 296, 299, 331 💬
20Diagnostic Test: Dry blood spot screening----[1] 296 💬
21DIMETHYL FUMARATE[1] Dimethyl fumarate[1] Dimethyl fumarate 💬 [1] KEAP1 💬 [6] Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Parkinson disease, Pathways in cancer, Ubiquitin mediated proteolysis 💬[5] 13, 20, 51, 86, 296 💬
22Filgrastim[1] Filgrastim[1] Filgrastim 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer 💬[30] 2, 6, 13, 25, 26, 28, 34, 35, 38, 40, 41, 42, 45, 46, 47, 49, 51, 60, 62, 63, 65, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
23Folic acid[1] Folic acid[2] Folic acid ,
Folate sodium 💬 		--[9] 6, 46, 49, 50, 84, 97, 118, 172, 296 💬
24Gold[1] Gold---[71] 2, 5, 6, 11, 13, 17, 19, 21, 22, 28, 34, 35, 46, 49, 50, 53, 54, 56, 57, 58, 60, 63, 64, 65, 66, 68, 71, 75, 76, 77, 79, 84, 85, 86, 88, 91, 93, 95, 96, 97, 98, 107, 113, 127, 137, 158, 162, 167, 171, 193, 206, 215, 218, 222, 223, 224, 226, 227, 228, 230, 235, 271, 291, 294, 296, 298, 299, 310, 318, 331, 340 💬
25Granulocyte Colony-Stimulating Factor----[2] 60, 296 💬
26High MCT formula----[1] 296 💬
27ICG Pulsion----[1] 296 💬
28ICG-Pulsion 25mg----[1] 296 💬
29IMIPENEM[1] Imipenem[2] Imipenem ,
Imipenem 💬 		--[3] 60, 296, 299 💬
30Indocyanine green[2] Indocyanine green,
Indocyanine green acid form		[1] Indocyanine green 💬 --[9] 22, 41, 46, 51, 96, 235, 278, 291, 296 💬
31Indocyanine Green (ICG)[2] Indocyanine green,
Indocyanine green acid form		[1] Indocyanine green 💬 --[1] 296 💬
32Intravenous immunoglobulin (IVIg)----[8] 14, 17, 19, 63, 65, 85, 164, 296 💬
33Kasai Portoenterostomy----[1] 296 💬
34Lactated Ringer----[1] 296 💬
35Lactobacillus casei[1] Lactobacillus casei[1] Lactobacillus casei 💬 --[3] 6, 97, 296 💬
36Lactobacillus casei rhamnosus (Lcr35)[1] Lactobacillus casei[1] Lactobacillus casei 💬 --[1] 296 💬
37Ligustrazine[1] Ligustrazine---[2] 46, 296 💬
38Lymph node and blood sampling----[1] 296 💬
39Magnesium[1] Magnesium---[23] 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬
40Magnesium gluconate[2] Magnesium,
Magnesium gluconate		[1] Magnesium gluconate 💬 --[2] 296, 297 💬
41Magnesium sulfate[2] Magnesium,
Magnesium sulfate		[1] Magnesium sulfate 💬 --[4] 11, 97, 296, 297 💬
42Maralixibat[1] Maralixibat[2] Maralixibat ,
Maralixibat chloride 💬 		[2] SLC10A1,
SLC10A2 💬 		[3] Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬[4] 296, 297, 299, 338 💬
43Maralixibat (formely SHP625 or LUM001)[1] Maralixibat[2] Maralixibat ,
Maralixibat chloride 💬 		[2] SLC10A1,
SLC10A2 💬 		[3] Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬[3] 296, 297, 338 💬
44Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 5-Product Name: Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 10-Product Name: Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 15-Product Name: Maralixibat (formely SHP625 or LUM001)Pharmaceutical Form: Oral solutionINN or Proposed INN: MARALIXIBAT CHLORIDECAS Number: 228113-66-4Concentration unit: mg/ml milligram(s)/millilitreConcentration type: equalConcentration number: 20-[1] Maralixibat[2] Maralixibat ,
Maralixibat chloride 💬 		[2] SLC10A1,
SLC10A2 💬 		[3] Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬[3] 296, 297, 338 💬
45MARALIXIBAT CHLORIDE[1] Maralixibat[2] Maralixibat ,
Maralixibat chloride 💬 		[2] SLC10A1,
SLC10A2 💬 		[3] Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬[3] 296, 297, 338 💬
46Maralixibat cloruro[1] Maralixibat[2] Maralixibat ,
Maralixibat chloride 💬 		[2] SLC10A1,
SLC10A2 💬 		[3] Bile secretion, Hepatitis B, Virion - Hepatitis viruses 💬[2] 296, 338 💬
47Meloxicam[1] Meloxicam[1] Meloxicam 💬 [1] PTGS2 💬 [22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[4] 46, 49, 271, 296 💬
48MEROPENEM[1] Meropenem[2] Meropenem ,
Meropenem 💬 		--[3] 60, 296, 299 💬
49Methylprednisolone[1] Methylprednisolone[2] Methylprednisolone ,
Methylprednisolone acetate 💬 		[1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[51] 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 111, 127, 145, 162, 164, 211, 222, 223, 224, 271, 283, 284, 285, 296, 300 💬
50N-acetyl Cysteine[1] Cysteine[2] L-Cysteine ,
Cysteine hydrochloride 💬 		--[6] 13, 34, 85, 88, 296, 310 💬
51N-Acetylcysteine[1] Acetylcysteine[1] Acetylcysteine 💬 --[14] 6, 13, 19, 20, 21, 49, 58, 85, 90, 111, 164, 296, 299, 337 💬
52Neomycin[1] Neomycin[3] Neomycin sulfate ,
Neomycin palmitate ,
Neomycin 💬 		--[3] 96, 97, 296 💬
53Norepinephrine[1] Norepinephrine[3] Noradrenaline ,
Norepinephrine bitartrate ,
Norepinephrine hydrochoride 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[2] 22, 296 💬
54Norepinephrine Bitartrate[1] Norepinephrine[3] Noradrenaline ,
Norepinephrine bitartrate ,
Norepinephrine hydrochoride 💬 		[9] ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C,
ADRB1,
ADRB2,
ADRB3 💬 		[16] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Dilated cardiomyopathy, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬[1] 296 💬
55Normal oral intake of the traditional formula----[1] 296 💬
56Normal Saline----[20] 6, 13, 17, 22, 36, 46, 49, 60, 70, 71, 79, 94, 96, 97, 210, 211, 226, 276, 296, 299 💬
57Obeticholic Acid[1] Obeticholic acid[1] Obeticholic acid 💬 [1] NR1H4 💬 [1] Bile secretion 💬[3] 93, 265, 296 💬
58OCA----[3] 93, 94, 296 💬
59OCA 0.1 mg----[1] 296 💬
60OCA 0.1mg----[1] 296 💬
61OCA 1.5mg----[1] 296 💬
62OCA 5mg----[1] 296 💬
63Ocaliva----[2] 93, 296 💬
64Odevixibat[1] Odevixibat[2] Odevixibat ,
Odevixibat hydrate 💬 		[1] SLC10A2 💬 [1] Bile secretion 💬[3] 296, 297, 338 💬
65Oral Vancomycin[1] Vancomycin[2] Vancomycin ,
Vancomycin hydrochloride 💬 		--[3] 94, 97, 296 💬
66Other Crystalloid----[1] 296 💬
67Other: Blood sampling----[14] 6, 13, 19, 46, 49, 51, 53, 58, 67, 127, 222, 266, 296, 299 💬
68Other: Control----[12] 6, 19, 67, 70, 75, 85, 96, 97, 162, 193, 226, 296 💬
69Other: explanted liver of BA patients sampling----[1] 296 💬
70Other: skin biopsy sampling----[1] 296 💬
71Pentoxifylline[1] Pentoxifylline[1] Pentoxifylline 💬 --[13] 6, 26, 46, 56, 84, 93, 96, 97, 113, 222, 223, 296, 298 💬
72PREDNISOLONE[1] Prednisolone[1] Prednisolone 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction 💬[48] 3, 11, 13, 14, 18, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 57, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 111, 113, 145, 162, 222, 223, 251, 269, 271, 296, 299, 300 💬
73Propanolol----[1] 296 💬
74Prophylactic oral antibiotics: compound sulfamethoxazole tablet (SMZ/TMP) + cefaclor[2] Cefaclor,
Sulfamethoxazole		[3] Cefaclor ,
Sulfamethoxazole ,
Cefaclor 💬 		--[1] 296 💬
75Propofol[1] Propofol[1] Propofol 💬 [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬 		[9] Cadherin signaling, GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[10] 3, 6, 21, 22, 34, 46, 70, 97, 98, 296 💬
76Rifaximin[1] Rifaximin[1] Rifaximin 💬 --[8] 6, 65, 93, 96, 97, 99, 296, 299 💬
77RITUXIMAB[1] Rituximab[1] Rituximab 💬 [1] MS4A1 💬 [1] Hematopoietic cell lineage 💬[54] 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 48, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 88, 93, 94, 96, 97, 162, 172, 222, 223, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
78Rocuronium[1] Rocuronium[1] Rocuronium bromide 💬 [16] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB2,
CHRNB3,
CHRNB4 💬 		[16] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[2] 70, 296 💬
79Sevoflurane[1] Sevoflurane[1] Sevoflurane 💬 --[8] 6, 21, 22, 34, 70, 98, 225, 296 💬
80Sevoflurane anesthetics[1] Sevoflurane[1] Sevoflurane 💬 --[1] 296 💬
81Stem Cell----[3] 2, 113, 296 💬
82Sulfamethoxazole[1] Sulfamethoxazole[1] Sulfamethoxazole 💬 --[8] 35, 44, 49, 61, 85, 223, 296, 299 💬
83Umbilical Cord Derived Mesenchymal Stem Cell (UC -MSC) Transplantation----[2] 93, 296 💬
84Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSCs)----[2] 46, 296 💬
85Ursodeoxycholic acid[1] Ursodeoxycholic acid[1] Ursodiol 💬 [1] NR1H4 💬 [1] Bile secretion 💬[10] 6, 46, 67, 84, 93, 94, 95, 96, 97, 296 💬
86Vancomycin[1] Vancomycin[2] Vancomycin ,
Vancomycin hydrochloride 💬 		--[9] 6, 13, 46, 70, 94, 96, 97, 296, 299 💬
87VO4CX----[1] 296 💬